P17.9 Muscle activity changes after needle electrical intramuscular stimulation – A rabbit model study

2006 ◽  
Vol 117 ◽  
pp. 207
Author(s):  
R.C. Chan ◽  
Y.Y. Cheng ◽  
S.H. Lee
Keyword(s):  
Muscle Activity ◽  
Rabbit Model ◽  
Model Study

A polymeric mini-stent designed to facilitate the vasectomy reversal operation. A rabbit model study

Biomaterials ◽  
2004 ◽  
Vol 25 (4) ◽  
pp. 729-734 ◽  
Author(s):  
Eric J. Vrijhof ◽  
Adriaan de Bruı̈ne ◽  
August A.B. Lycklama à Nijeholt ◽  
Leo H. Koole
Keyword(s):  
Rabbit Model ◽  
Model Study ◽  
Vasectomy Reversal

scholarly journals Detection of Pulmonary Embolism with Gallium-68 Macroaggregated Albumin Perfusion PET/CT: An Experimental Study in Rabbits

2020 ◽  
Author(s):  
Aziz Gültekin ◽  
Mustafa Çağdaş Çayır ◽  
Ayşe Uğur ◽  
Ferda Bir ◽  
Doğangün Yüksel
Keyword(s):  
Ct Perfusion ◽  
Rabbit Model ◽  
Histopathological Analysis ◽  
Model Study ◽  
Ventilation Imaging ◽  
Pet Ct ◽  
Medicine Physician ◽  
Animal Model Study ◽  
Gallium 68 ◽  
Sensitivity Specificity

Abstract This study was designed to evaluate the accuracy of to detect pulmonary emboli (PE) the Technegas SPECT/CT combined with 68Ga PET/CT in a rabbit model. One hour after artificial PE (n=6) and sham (n=6) models were created, Technegas SPECT/CT ventilation and 68Ga-MAA PET/CT perfusion scan (V/Q scan) were performed. All cases were performed ventilation imaging first. Technegas SPECT/CT and 68Ga-MAA PET/CT images were evaluated by a nuclear medicine physician who recorded the presence, number, and location of PE on a per-lobe basis. The sensitivity, specificity, and accuracy of Technegas SPECT/CT and 68Ga-MAA PET/CT for detecting PE were calculated using a histopathological evaluation as a reference standard.A total of 60 lung lobes were evaluated in 12 rabbits, and PE was detected in 20 lobes in V/Q scans and histopathological analysis. The overall sensitivity, specificity and accuracy were 100%, 100%, and 100%, respectively, for both the Technegas SPECT/CT and 68Ga-MAA PET/CT V/Q scans. Technegas/68Ga-MAA V/Q scans have good sensitivity, specificity and accuracy in the detection of PE in this animal model study.

scholarly journals Detection of Pulmonary Embolism with Gallium-68 Macroaggregated Albumin Perfusion PET/CT: An Experimental Study in Rabbits

2020 ◽  
Author(s):  
Aziz Gültekin ◽  
Mustafa Çağdaş Çayır ◽  
Ayşe Uğur ◽  
Ferda Bir ◽  
Doğangün Yüksel
Keyword(s):  
Ct Perfusion ◽  
Rabbit Model ◽  
Histopathological Analysis ◽  
Model Study ◽  
Ventilation Imaging ◽  
Pet Ct ◽  
Medicine Physician ◽  
Animal Model Study ◽  
Gallium 68 ◽  
Sensitivity Specificity

Abstract This study was designed to evaluate the accuracy of to detect pulmonary emboli (PE) the Technegas SPECT/CT combined with 68Ga PET/CT in a rabbit model. One hour after artificial PE (n=6) and sham (n=6) models were created, Technegas SPECT/CT ventilation and 68Ga-MAA PET/CT perfusion scan (V/Q scan) were performed. All cases were performed ventilation imaging first. Technegas SPECT/CT and 68Ga-MAA PET/CT images were evaluated by a nuclear medicine physician who recorded the presence, number, and location of PE on a per-lobe basis. The sensitivity, specificity, and accuracy of Technegas SPECT/CT and 68Ga-MAA PET/CT for detecting PE were calculated using a histopathological evaluation as a reference standard.A total of 60 lung lobes were evaluated in 12 rabbits, and PE was detected in 20 lobes in V/Q scans and histopathological analysis. The overall sensitivity, specificity and accuracy were 100%, 100%, and 100%, respectively, for both the Technegas SPECT/CT and 68Ga-MAA PET/CT V/Q scans. Technegas/68Ga-MAA V/Q scans have good sensitivity, specificity and accuracy in the detection of PE in this animal model study.

scholarly journals Effects of naloxone and yohimbine in polycystic ovary syndrome: a rabbit model study

2016 ◽  
Vol 46 ◽  
pp. 1265-1270 ◽  
Author(s):  
Sumera SAJJAD ◽  
Sadia TOBASSUM ◽  
Umer FAROOQ ◽  
Husna MALIK ◽  
Musadiq IDRIS
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Rabbit Model ◽  
Ovary Syndrome ◽  
Model Study

A threshold lung volume for optimal mechanical effects on upper airway airflow dynamics: studies in an anesthetized rabbit model

2012 ◽  
Vol 112 (7) ◽  
pp. 1197-1205 ◽  
Author(s):  
Kristina Kairaitis ◽  
Manisha Verma ◽  
Jason Amatoury ◽  
John R. Wheatley ◽  
David P. White ◽  
...  
Keyword(s):  
Lung Volume ◽  
Muscle Activity ◽  
Rabbit Model ◽  
Upper Airway ◽  
Flow Limitation ◽  
Volume Increase ◽  
Mechanical Effects ◽  
Pharyngeal Pressure ◽  
Volume Resistance ◽  
Spontaneously Breathing

Increasing lung volume improves upper airway airflow dynamics via passive mechanisms such as reducing upper airway extraluminal tissue pressures (ETP) and increasing longitudinal tension via tracheal displacement. We hypothesized a threshold lung volume for optimal mechanical effects on upper airway airflow dynamics. Seven supine, anesthetized, spontaneously breathing New Zealand White rabbits were studied. Extrathoracic pressure was altered, and lung volume change, airflow, pharyngeal pressure, ETP laterally (ETPlat) and anteriorly (ETPant), tracheal displacement, and sternohyoid muscle activity (EMG%max) monitored. Airflow dynamics were quantified via peak inspiratory airflow, flow limitation upper airway resistance, and conductance. Every 10-ml lung volume increase resulted in caudal tracheal displacement of 2.1 ± 0.4 mm (mean ± SE), decreased ETPlat by 0.7 ± 0.3 cmH2O, increased peak inspiratory airflow of 22.8 ± 2.6% baseline (all P < 0.02), and no significant change in ETPant or EMG%max. Flow limitation was present in most rabbits at baseline, and abolished 15.7 ± 10.5 ml above baseline. Every 10-ml lung volume decrease resulted in cranial tracheal displacement of 2.6 ± 0.4 mm, increased ETPant by 0.9 ± 0.2 cmH2O, ETPlat was unchanged, increased EMG%max of 11.1 ± 0.3%, and a reduction in peak inspiratory airflow of 10.8 ± 1.0%baseline (all P < 0.01). Lung volume, resistance, and conductance relationships were described by exponential functions. In conclusion, increasing lung volume displaced the trachea caudally, reduced ETP, abolished flow limitation, but had little effect on resistance or conductance, whereas decreasing lung volume resulted in cranial tracheal displacement, increased ETP and increased resistance, and reduced conductance, and flow limitation persisted despite increased muscle activity. We conclude that there is a threshold for lung volume influences on upper airway airflow dynamics.

scholarly journals A Rabbit Model Study to Determine the Efficacy of a Prototype Corneal Endothelium Protector during Cataract Surgery

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Annabel C. Y. Chew ◽  
Anita Chan ◽  
Monisha E. Nongpiur ◽  
Gary Peh ◽  
Veluchamy A. Barathi ◽  
...  
Keyword(s):  
Corneal Endothelium ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Rabbit Model ◽  
Cell Loss ◽  
Specular Microscopy ◽  
Endothelial Cell Loss ◽  
Surgical Time ◽  
Model Study ◽  
Significant Difference

Purpose. We evaluated the efficacy and safety of a mechanical device, the P-chute, in corneal endothelium preservation during phacoemulsification in a rabbit model. Methods. Twenty-four rabbits were randomly assigned into 2 groups. One eye of each rabbit underwent phacoemulsification that simulated the removal of a dense nucleus, with or without the P-chute. Serial slit-lamp examinations, anterior segment optical coherence tomography (ASOCT) scans, and specular microscopy were performed. Three rabbits from each group were sacrificed on postoperative days (PODs) 1, 5, 7, and 14. Histological analysis of the corneas was performed. Results. There was a trend towards lesser endothelial cell loss for the P-chute group at POD1 (4.9% versus 12.5%, p=0.53), POD5 (10.4% versus 12.2%, p=0.77), and POD7 (10.5% versus 17.2%, p=0.52). There was no significant difference in the corneal thickness (p=>0.05) between the 2 groups. The insertion of the device was challenging. The use of the P-chute only added an extra 15% to the surgical time. Conclusions. There was a trend towards better endothelium preservation with the P-chute even though the results were not statistically significant. We believe that the device could be useful in certain surgical situations. Further work is needed to improve the device insertion.

scholarly journals Influence of Implant Surface Topography on Primary Stability in a Standardized Osteoporosis Rabbit Model Study

2015 ◽  
Vol 6 (1) ◽  
pp. 143-152 ◽  
Author(s):  
Hiroshi Oue ◽  
Kazuya Doi ◽  
Yoshifumi Oki ◽  
Yusuke Makihara ◽  
Takayasu Kubo ◽  
...  
Keyword(s):  
Surface Topography ◽  
Rabbit Model ◽  
Primary Stability ◽  
Implant Surface ◽  
Model Study

scholarly journals Effect of Temperature-Sensitive Poloxamer Solution/Gel Material on Pericardial Adhesion Prevention: Supine Rabbit Model Study Mimicking Cardiac Surgery

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0143359 ◽  
Author(s):  
Hyun Kang ◽  
Yoon Sang Chung ◽  
Sang Wook Kim ◽  
Geun Joo Choi ◽  
Beom Gyu Kim ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Rabbit Model ◽  
Effect Of Temperature ◽  
Adhesion Prevention ◽  
Temperature Sensitive ◽  
Model Study

scholarly journals Are Ultrasound-Guided Ophthalmic Blocks Injurious to the Eye? A Comparative Rabbit Model Study of Two Ultrasound Devices Evaluating Intraorbital Thermal and Structural Changes

2012 ◽  
Vol 115 (1) ◽  
pp. 194-201 ◽  
Author(s):  
Howard D. Palte ◽  
Steven Gayer ◽  
Esdras Arrieta ◽  
Eric Scot Shaw ◽  
Izuru Nose ◽  
...  
Keyword(s):  
Structural Changes ◽  
Rabbit Model ◽  
Ultrasound Guided ◽  
Model Study
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