Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line

2006 ◽  
Vol 120 (3) ◽  
pp. 326-334 ◽  
Author(s):  
Hui-Ying Luan ◽  
Shye-Jye Tang ◽  
Winnie Yang ◽  
Chang-Youh Tsai ◽  
Guang-Huan Sun ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Line ◽  
Phosphoglycerate Kinase ◽  
Double Stranded Dna ◽  
Jurkat T Cell ◽  
Dna Antibodies

scholarly journals Increased intracellular Ca2+ is necessary for maximal expression of the proto-oncogene c-jun in the Jurkat T-cell line

1990 ◽  
Vol 267 (2) ◽  
pp. 349-351 ◽  
Author(s):  
M L Vandenplas ◽  
W L Mouton ◽  
S Vandenplas ◽  
A J Bester ◽  
M H Ricketts
Keyword(s):  
Signal Transduction ◽  
T Cells ◽  
T Cell ◽  
Cell Line ◽  
Time Course ◽  
Jurkat T Cell ◽  
Maximal Induction ◽  
Maximal Expression

The time course and signal-transduction requirements for proto-oncogene c-jun expression in T-cells were investigated. Expression of c-jun mRNA was evident at 30 min after stimulation. Both the activation of Ca2+/phospholipid-dependent kinase as well as an increased intracellular free Ca2+ concentration were necessary for the maximal induction of c-jun mRNA and synthesis of Jun protein 1 h after stimulation.

Cell calcium signalling induced by endogenous lectin carbohydrate interaction in the Jurkat T cell line

1996 ◽  
Vol 13 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Hermann Walzel ◽  
Jun Hirabayashi ◽  
Ken-Ichi Kasai ◽  
Josef Brock ◽  
Peter Neels
Keyword(s):  
T Cell ◽  
Cell Line ◽  
Calcium Signalling ◽  
Cell Calcium ◽  
Endogenous Lectin ◽  
Jurkat T Cell ◽  
Cell Calcium Signalling

Differential effects of A23187 and PMA on the induction of tolerance and priming in the Jurkat T cell line

1992 ◽  
Vol 34 (1) ◽  
pp. 27
Author(s):  
Brian M. Freed ◽  
Lisa Geiselhart ◽  
Theresa LaMena ◽  
David Conti ◽  
Neil Lempert
Keyword(s):  
T Cell ◽  
Cell Line ◽  
Differential Effects ◽  
Jurkat T Cell ◽  
Induction Of Tolerance

Definition of early Ca2+ signals induced by anti-CD3 antibody in a human Jurkat T-cell line using a selective protein kinase C inhibitor, Ro 31-8425

1993 ◽  
Vol 21 (4) ◽  
pp. 384S-384S
Author(s):  
LOUISE A. CONROY ◽  
JANET E. MERRITT ◽  
CHRYSANTHI F. GIAFI ◽  
ALAN G. LAMONT ◽  
TREVOR J. HALLAM
Keyword(s):  
Protein Kinase C ◽  
T Cell ◽  
Protein Kinase ◽  
Cell Line ◽  
Kinase C ◽  
Jurkat T Cell ◽  
Protein Kinase C Inhibitor ◽  
Definition Of

scholarly journals Effect of thimerosal, methylmercury, and mercuric chloride in Jurkat T Cell Line

2012 ◽  
Vol 5 (3) ◽  
pp. 159-161 ◽  
Author(s):  
Gianpaolo Guzzi ◽  
Paolo D. Pigatto ◽  
Francesco Spadari ◽  
Caterina A.M. La Porta
Keyword(s):  
T Cells ◽  
T Cell ◽  
Cell Line ◽  
Mercuric Chloride ◽  
Methyl Mercury ◽  
Leukemia Cell Line ◽  
Cellular Viability ◽  
Jurkat T Cells ◽  
Jurkat T Cell ◽  
Wide Range

ABSTRACT Mercury is a ubiquitous environmental toxicant that causes a wide range of adverse health effects in humans. Three forms of mercury exist: elemental, inorganic and organic. Each of them has its own profile of toxicity. The aim of the present study was to determine the effect of thimerosal, a topical antiseptic and preservative in vaccines routinely given to children, methyl mercury, and mercuric chloride on cellular viability measured by MTT in Jurkat T cells, a human T leukemia cell line. The treatment of Jurkat T cells with thimerosal caused a significant decrease in cellular viability at 1 μM (25%, p<0.05; IC50: 10 μM). Methyl mercury exhibited a significant decrease in cellular viability at 50 μM (33%, p<0.01; IC50: 65 μM). Mercuric chloride (HgCl2) did not show any significant change in cellular survival. Our findings showed that contrary to thimerosal and methyl mercury, mercuric chloride did not modify Jurkat T cell viability.

Isolation and characterisation of a CDw50 negative Jurkat T-cell line variant (PPL.1)

1993 ◽  
Vol 17 (1) ◽  
pp. 9-16 ◽  
Author(s):  
Francisco Lozano ◽  
Lourdes Places ◽  
José Alberola-Ila ◽  
Montserrat Milá ◽  
Neus Villamor ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Line ◽  
Jurkat T Cell

Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line

2000 ◽  
Vol 51 (2) ◽  
pp. 157-161 ◽  
Author(s):  
A. Peinnequin ◽  
A. Piriou ◽  
J. Mathieu ◽  
V. Dabouis ◽  
C. Sebbah ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Line ◽  
Thermal Effects ◽  
Jurkat T Cell ◽  
Induced Apoptosis

β-Adrenergic receptor-mediated calcium mobilization in the human Jurkat T cell line

Life Sciences ◽  
1995 ◽  
Vol 56 (18) ◽  
pp. 1443-1454 ◽  
Author(s):  
Haruo Takemura ◽  
Shinichi Hatta ◽  
Keiko Yamada ◽  
Hideyo Ohshika
Keyword(s):  
T Cell ◽  
Cell Line ◽  
Adrenergic Receptor ◽  
Calcium Mobilization ◽  
Jurkat T Cell
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