The Prognostic Effect of Changes in Tumor Stage and Nodal Status After Neoadjuvant Chemotherapy in Each Primary Breast Cancer Subtype

2018 ◽  
Vol 18 (2) ◽  
pp. e219-e229 ◽  
Author(s):  
Naoki Hayashi ◽  
Yuko Takahashi ◽  
Naoko Matsuda ◽  
Hiroko Tsunoda ◽  
Atsushi Yoshida ◽  
...  
2010 ◽  
Vol 1 (5) ◽  
pp. 747-754 ◽  
Author(s):  
REIKI NISHIMURA ◽  
TOMOFUMI OSAKO ◽  
YASUHIRO OKUMURA ◽  
MITSUHIRO HAYASHI ◽  
YASUO TOYOZUMI ◽  
...  

Author(s):  
Natalie Turner ◽  
Laura Biganzoli ◽  
Luca Malorni ◽  
Ilenia Migliaccio ◽  
Erica Moretti ◽  
...  

In the past, treatment decisions regarding adjuvant chemotherapy in early breast cancer (EBC) were made solely based on clinicopathologic factors. However, with increased awareness of the importance of underlying tumor biology, we are now able to use genomic analyses to determine molecular breast cancer subtype and thus identify patients with tumors that are chemotherapy resistant and unlikely to benefit from the addition of chemotherapy. Although genomics has allowed some patients to avoid chemotherapy—specifically those with luminal A–like breast cancer—these assays do not indicate which regimen is most appropriate. For this, consideration must be given to the combination of underlying tumor biology, tumor stage, and patient characteristics, such as age and tolerability of side effects.


2017 ◽  
Vol 22 (4) ◽  
pp. 394-401 ◽  
Author(s):  
Rosalind P. Candelaria ◽  
Roland L. Bassett ◽  
William Fraser Symmans ◽  
Maheshwari Ramineni ◽  
Stacy L. Moulder ◽  
...  

2018 ◽  
Vol 25 (12) ◽  
pp. 3535-3540 ◽  
Author(s):  
Lucy M. De La Cruz ◽  
Michael O. Harhay ◽  
Paul Zhang ◽  
Stacy Ugras

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