Effects of aqueous polymeric surfactants on silicone-hydrogel soft- contact-lens wettability and bacterial adhesion of Pseudomonas aeruginosa

2012 ◽  
Vol 35 (4) ◽  
pp. 155-162 ◽  
Author(s):  
Victoria B. Tran ◽  
Ye Suel Sung ◽  
Kendra Copley ◽  
C.J. Radke
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Contact Lens ◽  
Bacterial Adhesion ◽  
Polymeric Surfactants ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lens

scholarly journals Bacterial adhesion to Conventional and Silicone hydrogel contact lenses

2021 ◽  
Vol 23 (1) ◽  
pp. 25-35
Author(s):  
Eghosasere Iyamu ◽  
Frederick Osaro Ekhaise
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Contact Lens ◽  
Bacterial Adhesion ◽  
Contact Lenses ◽  
Bacterial Species ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lenses ◽  
Lens Wear

Purpose: The aim of this study was to investigate the adhesion of bacteria to worn silicone hydrogel and conventional soft contact lenses.Methods: Bacterial adhesion experiments / assays were performed on 24 worn and 6 unworn soft contact lenses each of different materials (high- and low- gas permeable lenses) using the strains such as Pseudomonas aeruginosa ATCC 27853 and Staphylococcus aureus ATCC 25923.Results: P. aeruginosa adhered in increased number to worn than unworn Lotrafilcon A and conventional lenses. However, a higher number of P. aeruginosa adhered to unworn than worn Lotrafilcon B, the difference in the mean adhesion was not significant (p = 0.66). S. aureus adhered in significantly decreased number to worn Lotrafilcon A, nelfilcon A, nesofilcon A, etafilcon A and omafilcon A (p<0.05); butsignificantly higher number adhered to worn than unworn polymacon (p<0.05). Lens wear had no effect on the adhesion of S. aureus to Lotrafilcon B (p>0.05). The least adhesion of P. aeruginosa to worn contact lenses was seen with polymacon, while S. aureus adhered in least number to worn Lotrafilcon A compared to the other contact lens materials that demonstrated the same trend in adhesion.Conclusion: The higher adhesion of P. aeruginosa to worn lenses is consistent with the claim that it is the most implicated in all culture-positive contact lens related bacterial keratitis. Lens wear has different effects on bacterial adhesion, which may be due to type of lens materials and bacterial species/genera studied. Keywords: Silicone hydrogel lenses, conventional lenses, Pseudomonas aeruginosa, Staphylococcus aureus, bacterial adhesion.

scholarly journals Performance of Three Multipurpose Disinfecting Solutions with a Silicone Hydrogel Contact Lens

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Nery García-Porta ◽  
Laura Rico-del-Viejo ◽  
Helena Ferreira-Neves ◽  
Sofia C. Peixoto-de-Matos ◽  
Antonio Queirós ◽  
...  
Keyword(s):  
Contact Lens ◽  
Clinical Performance ◽  
The Other ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lens ◽  
Comfort Rating ◽  
Analogue Scales ◽  
Lens Wear

Purpose. To evaluate the clinical performance of a silicone hydrogel (Si-Hy) soft contact lens (CL) in combination with three different multipurpose disinfecting solutions (MPDSs).Methods. This was a prospective, randomized, single-masked, crossover, and comparative study in which 31 habitual soft CL wearers were randomly assigned to one of the three MPDSs (Synergi, COMPLETE RevitaLens, and OPTI-FREE PureMoist) for 1 month with a 1-week wash-out period between each exposure. All subjects were successfully refitted with a Si-Hy CL (Biofinity). Subjects were then scheduled for follow-up visits after 1 month of lens wear, being evaluated at 2 and 8 hours after lens insertion. Visual Analogue Scales (VAS) were used to gauge comfort rating.Results. The tarsal conjunctiva showed a significantly different degree of lid redness between the MPDSs at the 2-hour visit (P<0.05, Kruskal-Wallis test), being lower for COMPLETE RevitaLens compared to the other two MPDSs (Mann-WhitneyUtest). Furthermore, a significantly different degree of lid roughness at the 8-hour visit was seen (P<0.05, Kruskal-Wallis test), being higher for Synergi (Mann-WhitneyUtest). The subjective comfort was similar with the three MPDSs.Conclusion.Tarsal conjunctival response should be also considered in the context of the clinical performance of MPDs at the ocular surface.

Compatibility of two new silicone hydrogel contact lenses with three soft contact lens multipurpose solutions

2008 ◽  
Vol 28 (4) ◽  
pp. 373-381 ◽  
Author(s):  
Jacinto Santodomingo-Rubido ◽  
Eva Barrado-Navascués ◽  
María-José Rubido-Crespo ◽  
Keiji Sugimoto ◽  
Tadashi Sawano
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lens

scholarly journals Changes in Tear Cytokines Following a Short Period of Daily and Overnight Silicone Hydrogel Lens Wear

2017 ◽  
Vol 1 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Kim Duong ◽  
Cecilia Chao ◽  
Mark Willcox ◽  
Kathryn Richdale
Keyword(s):  
Contact Lens ◽  
Diurnal Fluctuation ◽  
Soft Contact ◽  
Contact Lens Wear ◽  
Silicone Hydrogel ◽  
Soft Contact Lens ◽  
Inflammatory Status ◽  
Tnf Α ◽  
Short Period ◽  
Lens Wear

Background and Objective: To investigate changes in ocular surface inflammatory markers after daily and overnight silicone hydrogel contact lens wear in healthy wearers. Material and Methods: Twenty-six experienced soft contact lens subjects were evaluated at baseline, after 1-day of silicone hydrogel lens wear, and after 1-night of wear. Basal tears were collected at each visit and tear cytokine concentrations were quantified using multiplex [interleukin (IL)-1β, IL-6, IL-10, IL-12(p70), IL-17A and tumor necrosis factor (TNF)-α] or ELISA (IL-8) kits. A historical control group of 27 non-contact lens wearers was used to compare absolute concentrations and diurnal variations in tear cytokine concentrations. Changes in cytokine concentrations were analyzed using linear mixed models. Linear regression with bootstrapping was used to assess whether changes in IL-1β concentrations were associated with changes in other cytokines. Results: IL-8 concentrations decreased after 1 day of silicone hydrogel contact lens wear and returned to baseline levels the next morning (p=0.04). This same diurnal fluctuation was seen in non-contact lens wearers (p=0.03). With daily contact lens wear, there was a significant positive correlation between the changes in IL-1β and IL-8, TNF-α, IL-10 and IL-12(p70) (all p<0.03). With overnight contact lens wear, there were significant positive correlations between the changes in IL-1β and IL-6, IL-17A and TNF-α (all p<0.01). Conclusion: A short period of daily and overnight silicone hydrogel lens wear does not significantly alter the inflammatory status in adapted soft contact lens wearers.

scholarly journals Role of the Water Gradient Structure in Inhibiting Thin Aqueous Layer Break in Silicone Hydrogel-Soft Contact Lens

2021 ◽  
Vol 10 (11) ◽  
pp. 5
Author(s):  
Hisataka Fujimoto ◽  
Shintaro Ochi ◽  
Tsutomu Yamashita ◽  
Yasushi Inoue ◽  
Junichi Kiryu
Keyword(s):  
Contact Lens ◽  
Gradient Structure ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lens ◽  
Water Gradient ◽  
Aqueous Layer

scholarly journals Quality of Vision with Spectacles, Special Silicone Hydrogel and Gas Permeable Contact Lenses in Keratoconic Patients

2013 ◽  
Vol 2 (2) ◽  
pp. 56-59 ◽  
Author(s):  
Jose M González-Méijome ◽  
Sofia Claudia Peixoto-de-Matos ◽  
Antonio Queiros ◽  
Jorge M Jorge ◽  
Alberto Diaz-Rey
Keyword(s):  
Visual Acuity ◽  
Contact Lens ◽  
Contact Lenses ◽  
Soft Contact ◽  
Low Contrast ◽  
Silicone Hydrogel ◽  
Soft Contact Lens ◽  
Quality Of Vision ◽  
Spectacle Correction

ABSTRACT Purpose To evaluate optical quality and visual function in keratoconus patients corrected with RGP contact lenses and a novel special design of silicone hydrogel contact lens. Materials and methods Twelve eyes of six patients with keratoconus were enrolled to experience a new soft contact lens (Soft-K) for keratoconus made of a silicone-hydrogel material and the outcomes were compared to the performance with gas permeable lenses and spectacles. The three situations were compared for monocular and binocular high (100%) and low contrast (10%) ETDRS LogMAR visual acuity and contrast sensitivity function (CSF). Results On average, there was an improvement of more than two lines in visual acuity over spectacle correction and this is statistically significant for both gas permeable (GP) and Soft-K lens (p < 0.001). Visual acuity was not significantly different between GP and Soft-K lens for high contrast acuity but was slightly higher with GP lens for low contrast under binocular conditions. Monocular CSF showed a marked improvement with the Soft-K lens and GP, compared to spectacles correction, particularly for medium and high frequencies; conversely. Conclusion Soft-K silicone hydrogel soft contact lens produces a clinical and statistically significant improvement in visual acuity and contrast sensitivity function over spectacle correction. How to cite this article González-Méijome JM, Peixoto-de- Matos SC, Queiros A, Jorge JM, Diaz-Rey A. Quality of Vision with Spectacles, Special Silicone Hydrogel and Gas Permeable Contact Lenses in Keratoconic Patients. Int J Kerat Ect Cor Dis 2013;2(2):56-59.

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