GENETIC DELETION OF NATURAL KILLER CELL TRANSFORMING GROWTH FACTOR-β SIGNALING PROTECTS MICE FROM HYPOXIA-INDUCED PULMONARY HYPERTENSION

K Coyle; M Ratsep; L Hilton; M Vandenbroek; K Laverty; M Mitchell; M Ormiston

doi:10.1016/j.cjca.2021.07.225

GENETIC DELETION OF NATURAL KILLER CELL TRANSFORMING GROWTH FACTOR-β SIGNALING PROTECTS MICE FROM HYPOXIA-INDUCED PULMONARY HYPERTENSION

Canadian Journal of Cardiology ◽

10.1016/j.cjca.2021.07.225 ◽

2021 ◽

Vol 37 (10) ◽

pp. S115

Author(s):

K Coyle ◽

M Ratsep ◽

L Hilton ◽

M Vandenbroek ◽

K Laverty ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Transforming Growth Factor ◽

Killer Cell ◽

Transforming Growth Factor Β ◽

Genetic Deletion ◽

Cell Transforming

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Augmentation of natural killer cell activity in mice by oral administration of transforming growth factor‐β

Immunology ◽

10.1046/j.1365-2567.1998.00652.x ◽

1998 ◽

Vol 95 (3) ◽

pp. 460-465 ◽

Cited By ~ 8

Author(s):

ISHIZAKA ◽

KIMOTO ◽

KANDA ◽

SAITO

Keyword(s):

Growth Factor ◽

Natural Killer Cell ◽

Oral Administration ◽

Natural Killer ◽

Transforming Growth Factor ◽

Natural Killer Cell Activity ◽

Killer Cell ◽

Cell Activity ◽

Transforming Growth Factor Β ◽

Killer Cell Activity

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Transforming Growth Factor-β-activated Kinase 1 Regulates Natural Killer Cell-mediated Cytotoxicity and Cytokine Production

Journal of Biological Chemistry ◽

10.1074/jbc.m111.261917 ◽

2011 ◽

Vol 286 (36) ◽

pp. 31213-31224 ◽

Cited By ~ 20

Author(s):

Kamalakannan Rajasekaran ◽

Haiyan Chu ◽

Pawan Kumar ◽

Yechen Xiao ◽

Mathew Tinguely ◽

...

Keyword(s):

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Cytokine Production ◽

Transforming Growth Factor ◽

Killer Cell ◽

Transforming Growth Factor Β

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Platelet-Derived Transforming Growth Factor-β Down-Regulates NKG2D Thereby Inhibiting Natural Killer Cell Antitumor Reactivity

Cancer Research ◽

10.1158/0008-5472.can-09-2123 ◽

2009 ◽

Vol 69 (19) ◽

pp. 7775-7783 ◽

Cited By ~ 212

Author(s):

Hans-Georg Kopp ◽

Theresa Placke ◽

Helmut Rainer Salih

Keyword(s):

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Transforming Growth Factor ◽

Killer Cell ◽

Transforming Growth Factor Β

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Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ

Nature Immunology ◽

10.1038/ni1197 ◽

2005 ◽

Vol 6 (6) ◽

pp. 600-607 ◽

Cited By ~ 281

Author(s):

Yasmina Laouar ◽

Fayyaz S Sutterwala ◽

Leonid Gorelik ◽

Richard A Flavell

Keyword(s):

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Transforming Growth Factor ◽

Killer Cell ◽

Transforming Growth Factor Β ◽

Interferon Γ ◽

T Helper ◽

Helper Type

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Manipulating Interleukin-15 and Transforming Growth Factor-β Signaling Augments Natural Killer Cell Homeostasis and Protects from Experimental Pulmonary Arterial Hypertension

10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2678 ◽

2020 ◽

Author(s):

M. Ratsep ◽

L.R. Hilton ◽

M. Mitchell ◽

E. Vivier ◽

M.L. Ormiston

Keyword(s):

Growth Factor ◽

Pulmonary Arterial Hypertension ◽

Natural Killer Cell ◽

Arterial Hypertension ◽

Natural Killer ◽

Transforming Growth Factor ◽

Killer Cell ◽

Transforming Growth Factor Β ◽

Interleukin 15 ◽

Pulmonary Arterial

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A porcine intrauterine 4-mda component with transforming growth factor-beta activity suppresses natural killer cell responses.

Journal of Animal Science ◽

10.2527/2000.7871900x ◽

2000 ◽

Vol 78 (7) ◽

pp. 1900 ◽

Cited By ~ 5

Author(s):

E C Segerson ◽

P K Beetham

Keyword(s):

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Killer Cell ◽

Beta Activity ◽

Cell Responses ◽

Growth Factor Beta

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Boosting Natural Killer Cell-Based Cancer Immunotherapy with Selenocystine/Transforming Growth Factor-Beta Inhibitor-Encapsulated Nanoemulsion

ACS Nano ◽

10.1021/acsnano.9b10103 ◽

2020 ◽

Vol 14 (9) ◽

pp. 11067-11082 ◽

Cited By ~ 3

Author(s):

Chang Liu ◽

Haoqiang Lai ◽

Tianfeng Chen

Keyword(s):

Growth Factor ◽

Natural Killer Cell ◽

Cancer Immunotherapy ◽

Natural Killer ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Killer Cell ◽

Growth Factor Beta

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Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor- 1

Haematologica ◽

10.3324/haematol.2010.039743 ◽

2011 ◽

Vol 96 (9) ◽

pp. 1302-1309 ◽

Cited By ~ 209

Author(s):

M. J. Szczepanski ◽

M. Szajnik ◽

A. Welsh ◽

T. L. Whiteside ◽

M. Boyiadzis

Keyword(s):

Acute Myeloid Leukemia ◽

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Myeloid Leukemia ◽

Transforming Growth Factor ◽

Cell Function ◽

Killer Cell ◽

Natural Killer Cell Function ◽

Acute Myeloid

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Faculty Opinions recommendation of A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726313808.793517656 ◽

2016 ◽

Author(s):

Vinicio de Jesus Perez

Keyword(s):

Pulmonary Hypertension ◽

Growth Factor ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β

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Abstract A11: Targeting vascular endothelial growth factor in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia

10.1158/1538-7445.tme16-a11 ◽

2016 ◽

Author(s):

Magali Castells ◽

Ralph Klose ◽

Dagmar Gotthardt ◽

Eva-Maria Putz ◽

Ewelina Krzywinska ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Natural Killer Cell ◽

Natural Killer ◽

Killer Cell ◽

Myeloid Cells ◽

Vascular Endothelial ◽

Cell Responses ◽

Endothelial Growth Factor

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