NATURAL HISTORY OF MITRAL ANNULUS CALCIFICATION AND CALCIFIC MITRAL VALVE DISEASE

2021 ◽  
Vol 37 (10) ◽  
pp. S76-S77
Author(s):  
N Willner ◽  
I Burwash ◽  
L Beauchesne ◽  
B Vulesevic ◽  
K Ascah ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Natural History ◽  
Mitral Valve Disease ◽  
Mitral Annulus ◽  
Valve Disease ◽  
Mitral Annulus Calcification ◽  
History Of

scholarly journals Natural history of coexistent tricuspid regurgitation in patients with degenerative mitral valve disease: Implications for future guidelines

2014 ◽  
Vol 148 (6) ◽  
pp. 2802-2810 ◽  
Author(s):  
Andrew B. Goldstone ◽  
Jessica L. Howard ◽  
Jeffrey E. Cohen ◽  
John W. MacArthur ◽  
Pavan Atluri ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Natural History ◽  
Tricuspid Regurgitation ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
History Of

“Surgical Treatment of Degenerative Mitral Valve Disease-Causing Mitral Regurgitation: State Of The Art”

2021 ◽  
Vol 8 (07) ◽  
Author(s):  
Md Faisal Talukder
Keyword(s):  
Mitral Valve ◽  
Natural History ◽  
Mitral Regurgitation ◽  
Clinical Outcomes ◽  
Treatment Strategy ◽  
Mitral Valve Disease ◽  
State Of The Art ◽  
Postoperative Mortality ◽  
Valve Disease ◽  
History Of

Degenerative Mitral Valve Disease (DMVD) is common in developed countries that frequently causes mitral regurgitation (MR). The natural history of DMVD is not well demonstrated. Therefore, timely and suitable interventions are the determinant of post-intervention clinical outcomes, life quality, and life expectancy of patients. The severity of MR can be precisely assessed by doppler-echocardiographic imaging. However, no medical management has been proven to be effective in averting the volume overload related sequel of asymptomatic degenerative MR. Therefore, mitral valve surgery (MVS) is the gold standard treatment strategy for DMVD. Notwithstanding, MVS is the only sorts of treatment strategy which provides long term natural and complication-free clinical outcome to otherwise healthy DMVD patients. However, mitral valve (MV) repair provides better clinical outcomes compared to MV replacement, along with the significant reduction of postoperative mortality rate about 70%. Currently, MVS is carried out using minimally invasive techniques or robotic-assisted techniques. Nonetheless, MVS using percutaneous techniques is evolving in the treatment for DMVD patients. This state-of-the-art-review is aimed to delineate the recent knowledge of DMVD, which includes the natural history of the disease, diagnostic modalities, recent treatment strategies, and clinical follow-up results.

scholarly journals Myxomatous Mitral Valve Disease with Mitral Valve Prolapse and Mitral Annular Disjunction: Clinical and Functional Significance of the Coincidence

2021 ◽  
Vol 8 (2) ◽  
pp. 9
Author(s):  
Nina C. Wunderlich ◽  
Siew Yen Ho ◽  
Nir Flint ◽  
Robert J. Siegel
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Morphological Changes ◽  
Morphological Characteristics ◽  
Mitral Annulus ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Valve Disease ◽  
Left Ventricular Myocardium ◽  
Basal Portion

The morphological changes that occur in myxomatous mitral valve disease (MMVD) involve various components, ultimately leading to the impairment of mitral valve (MV) function. In this context, intrinsic mitral annular abnormalities are increasingly recognized, such as a mitral annular disjunction (MAD), a specific anatomical abnormality whereby there is a distinct separation between the mitral annulus and the left atrial wall and the basal portion of the posterolateral left ventricular myocardium. In recent years, several studies have suggested that MAD contributes to myxomatous degeneration of the mitral leaflets, and there is growing evidence that MAD is associated with ventricular arrhythmias and sudden cardiac death. In this review, the morphological characteristics of MAD and imaging tools for diagnosis will be described, and the clinical and functional aspects of the coincidence of MAD and myxomatous MVP will be discussed.

scholarly journals Mitral annulus dynamics in myxomatous mitral valve disease

2021 ◽  
Vol 31 (1) ◽  
pp. 66-75
Author(s):  
Maria-Magdalena Gurzun ◽  
Monica Rosca ◽  
Andreea Calin ◽  
Carmen Beladan ◽  
Marinela Serban ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Mitral Valve Disease ◽  
Current Trend ◽  
Mitral Annulus ◽  
Valve Disease ◽  
Valve Repair ◽  
Functional Changes ◽  
Different Types

Myxomatous mitral valve disease (MVD) is a common disorder in which the entire mitral valve apparatus seems to be involved. Mitral valve repair is nowadays the method of choice for the correction of mitral regurgitation but the optimal shape and flexibility of the annuloplasty ring remain controversial. Considering that myxomatous MVD covers a wide spectrum from limited fi bro-elastic deficiency to extensive Barlow disease, we presume that the mitral annulus morphological and functional changes are likely different in different types of myxomatous MVD. We analyze the 3-dimensional geometry and the dynamics of the mitral annulus in 110 patients with significant mitral regurgitation due to different types of myxomatous mitral valve disease and 40 normal subjects using 3D transesophageal echocardiography. The mitral annulus differs in patients with limited MVD, extensive MVD and in normal controls in terms of size, shape, and dynamics. Patients with limited MVD have larger, flatter, dysfunctional and more mobile mitral annulus compared to normal, while patients with extensive MVD have even larger, fl atter and more dysfunctional mitral annulus, with reduced mobility. The non-planar dynamics has different patterns during systole, according to the extension of MV disease. Our data may be important for the appropriate choose of annuloplasty mitral annulus in mitral valve repair, the current trend being to choose the ring according to the underlying pathology.

The playmaker of the mitral valve disease: Mitral annulus

2020 ◽  
Vol 316 ◽  
pp. 205-206
Author(s):  
Bilge Duran Karaduman ◽  
Hüseyin Ayhan ◽  
Telat Keleş ◽  
Engin Bozkurt
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Mitral Annulus ◽  
Valve Disease

scholarly journals Long-axis fractional shortening and mitral annulus motion in dogs

2016 ◽  
Vol 37 (5) ◽  
pp. 3115 ◽  
Author(s):  
Marlos Gonçalves Sousa ◽  
Fabio Nelson Gava ◽  
Jorge Cardoso da Silva Filho ◽  
Sheila Nogueira Saraiva da Silva ◽  
Rafael Rodrigues Camacho ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Mitral Annulus ◽  
Left Ventricular ◽  
Cardiac Contraction ◽  
Valve Disease ◽  
Strain And Strain Rate ◽  
Echocardiographic Parameters ◽  
Myocardial Fibers ◽  
Fractional Shortening

Ventricular systolic dynamics involves the contraction of transverse and longitudinal myocardial fibers. Unfortunately, only the activity of the transverse myocardial fibers is foreseen by the standard systolic echocardiographic parameters. Although strain and strain rate have been used to assess the radial, circumferential and longitudinal planes of cardiac contraction, such analysis requires advanced equipment which is not always available in veterinary medicine. On the contrary, some unusual parameters may be recorded via standard methodology, allowing for the specific evaluation of left ventricular longitudinal contractility. In this study, the longitudinal contractile activity was evaluated using the long-axis fractional shortening and the mitral annulus motion, which were compared with several standard echocardiographic parameters in 14 beagles, including seven with asymptomatic mitral valve disease. The long-axis fractional shortening was positively correlated with both the mitral annulus motion and the end-diastolic left-ventricular diameter. Also, a significant correlation was found to exist between the mitral annulus motion and the left-ventricular end-diastolic diameter, which is likely supportive of its preload dependency. Even though no difference was documented in either mitral annulus motion or long-axis fractional shortening between healthy dogs and dogs with mitral valve disease, the latter only included animals with minimal cardiac remodeling, with no overt compromise of systolic function. Since it is possible to obtain these two parameters with any echocardiographic equipment, their inclusion in the routine exam would probably add information regarding the activity of the longitudinal myocardial fibers, whose functional deterioration supposedly occurs prior to the impairment of transverse fibers.

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