scholarly journals Acute Kidney Injury Following Aortic Valve Replacement in Patients Without Chronic Kidney Disease

2021 ◽  
Vol 37 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Noriaki Moriyama ◽  
Teemu Laakso ◽  
Peter Raivio ◽  
Sebastian Dahlbacka ◽  
Eeva-Maija Kinnunen ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Kidney Injury

scholarly journals Incidence of Acute Kidney Injury in Patients with Chronic Renal Insufficiency: Transcatheter versus Surgical Aortic Valve Replacement

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Michael Catalano ◽  
Dishen Lin ◽  
Hugh Cassiere ◽  
Nina Kohn ◽  
Bruce Rutkin ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Aortic Valve ◽  
Renal Insufficiency ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Kidney Injury ◽  
Surgical Aortic Valve Replacement ◽  
Postoperative Aki

Objectives. The objective of this study is to determine incidence of acute kidney injury (AKI) associated with transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in patients with preexisting chronic kidney disease. Background. The incidence of AKI in patients with preexisting renal insufficiency undergoing TAVR versus SAVR is not well described. Methods. All patients with preexisting chronic kidney disease who underwent SAVR for aortic stenosis with or without concomitant coronary artery bypass grafting or TAVR from 5/2008 to 6/2017. Patients requiring preoperative hemodialysis were excluded. Chronic kidney disease was defined as an estimated glomerular filtrate rate (eGFR) of < 60 mL/min/1.73 m2. The incidence of postoperative AKI was compared using the RIFLE classification system for acute kidney injury. Results. A total of 406 SAVR patients and 407 TAVR patients were included in this study. TAVR patients were older and had lower preoperative eGFR as compared to SAVR patients. Covariate adjustment using propensity score between the two groups showed that SAVR patients were more likely to have a more severe degree of postoperative AKI as compared to TAVR patients (OR = 4.75; 95% CI: 3.15, 7.17; p <.001). SAVR patients were more likely to require dialysis postoperatively as compared to TAVR patients (OR = 4.55; 95% CI: 1.29, 15.99; p <.018). Conclusion. In patients with preexisting chronic kidney disease, TAVR was associated with significantly less AKI as compared to SAVR.

scholarly journals Acute kidney injury and acute kidney recovery following Transcatheter Aortic Valve Replacement

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255806
Author(s):  
Marilou Peillex ◽  
Benjamin Marchandot ◽  
Kensuke Matsushita ◽  
Eric Prinz ◽  
Sebastien Hess ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Replacement ◽  
Kidney Injury ◽  
Transcatheter Aortic Valve ◽  
Dismal Prognosis ◽  
Definition Of

Background Acute kidney injury (AKI) is associated with a dismal prognosis in Transcatheter Aortic Valve replacement (TAVR). Acute kidney recovery (AKR), a phenomenon reverse to AKI has recently been associated with better outcomes. Methods Between November 2012 to May 2018, we explored consecutive patients referred to our Heart Valve Center for TAVR. AKI was defined according to the VARC-2 definition. Mirroring the VARC-2 definition of AKI, AKR was defined as a decrease in serum creatinine (≥50%) or ≥25% improvement in GFR up to 72 hours after TAVR. Results AKI and AKR were respectively observed in 8.3 and 15.7% of the 574 patients included. AKI and AKR patients were associated to more advanced kidney disease at baseline. At a median follow-up of 608 days (range 355–893), AKI and AKR patients experienced an increased cardiovascular mortality compared to unchanged renal function patients (14.6% and 17.8% respectively, vs. 8.1%, CI 95%, p<0.022). Chronic kidney disease, (HR: 3.9; 95% CI 1.7–9.2; p < 0.001) was the strongest independent factor associated with AKI similarly to baseline creatinine level (HR: 1; 95% CI 1 to 1.1 p < 0.001) for AKR. 72-hours post procedural AKR (HR: 2.26; 95% CI 1.14 to 4.88; p = 0.021) was the strongest independent predictor of CV mortality. Conclusions Both AKR and AKI negatively impact long term clinical outcomes of patients undergoing TAVR.

scholarly journals Clinical impact of baseline chronic kidney disease in patients undergoing transcatheter or surgical aortic valve replacement

2018 ◽  
Vol 93 (4) ◽  
pp. 740-748 ◽  
Author(s):  
Andres M. Pineda ◽  
J. Kevin Harrison ◽  
Neal S. Kleiman ◽  
Michael J. Reardon ◽  
John V. Conte ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Clinical Impact ◽  
Surgical Aortic Valve Replacement
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