THE IMPACT OF A REGIONAL ST ELEVATION MYOCARDIAL INFARCTION PROTOCOL ON REPERFUSION DELIVERY AND CLINICAL OUTCOMES OVER 11 YEARS: INSIGHTS FROM THE VANCOUVER COASTAL HEALTH AUTHORITY ST ELEVATION MYOCARDIAL INFARCTION PROGRAM

2019 ◽  
Vol 35 (10) ◽  
pp. S10
Author(s):  
G. Wong ◽  
C. Fordyce ◽  
T. Lee ◽  
M. Perry Arnesen ◽  
M. Mackay ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Clinical Outcomes ◽  
Health Authority ◽  
St Elevation Myocardial Infarction ◽  
St Elevation ◽  
The Impact

scholarly journals The impact of anthropomorphic indices on clinical outcomes in patients with acute ST-elevation myocardial infarction

2007 ◽  
Vol 28 (4) ◽  
pp. 415-424 ◽  
Author(s):  
R. H. Mehta ◽  
R. M. Califf ◽  
J. Garg ◽  
H. D. White ◽  
F. Van de Werf ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Clinical Outcomes ◽  
St Elevation Myocardial Infarction ◽  
St Elevation ◽  
The Impact

The Impact of Out-of-Hours Presentation on Clinical Outcomes in ST-Elevation Myocardial Infarction

2020 ◽  
Vol 29 (6) ◽  
pp. 814-823 ◽  
Author(s):  
Sinjini Biswas ◽  
Angela Brennan ◽  
Stephen J. Duffy ◽  
Nick Andrianopoulos ◽  
William Chan ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Clinical Outcomes ◽  
St Elevation Myocardial Infarction ◽  
Out Of Hours ◽  
St Elevation ◽  
The Impact

Early vascular responses to ultrathin biodegradable polymer sirolimus-eluting stent for the treatment of st-elevation myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
Y Oishi ◽  
T Shinke ◽  
H Tanaka ◽  
K Ogura ◽  
K Arai ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Clinical Outcomes ◽  
Antiplatelet Therapy ◽  
St Elevation Myocardial Infarction ◽  
Current Generation ◽  
Vascular Responses ◽  
Post Procedure ◽  
St Elevation ◽  
Sirolimus Eluting Stent

Abstract Background Recent clinical study suggests newer-generation drug-eluting stents (DES) that combine ultrathin strut and nano-coating with biodegradable polymers sirolimus-eluting stent (BP-SES) could improve long-term clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) over current generation DES. However, safety profiles in very early phase have not been systematically addressed. Objective and method We exploratory investigate early vascular response following BP-SES implantation in patients with STEMI to reveal mechanism of the favorable clinical outcomes in recent studies using frequency domain-optical coherence tomography (FD-OCT). Consecutive twenty patients with STEMI who underwent FD-OCT immediately after primary PCI and were eligible for follow-up FD-OCT at 2 weeks after implantation were enrolled between June 2018 and November 2019. Results Twenty patients (age 62.7±11.3 years, male 85.0%) were enrolled with frequencies of hypertension (45.0%), diabetes mellitus (35.0%), dyslipidemia (55.0%) and smoking (80.0%). Aspiration catheter were used in all patients, and 1.13±0.34 stents were used. Only one patient (5.0%) received chronic antiplatelet therapy with aspirin prior to the onset of STEMI. All patients started to receive prasugrel as thienopyridine from this event and continued dual antiplatelet therapy for 2 weeks. The percentage of uncovered struts significantly decreased from post-procedure to 2W follow-up (69±18% post-procedure versus 30±11% at 2W follow up, p<0.0001). Malapposed struts also decreased (5.6±5.7% post-procedure versus0.9±1.2% at 2W follow up, p<0.0001).The average protrusion area of athero-thrombotic burden numerically decreased (0.37±0.19 at post-procedure versus 0.34±0.14 mm2 at 2W follow up, p=0.19) and its volume showed similar tendency (10.60±6.40 at post-procedure versus 9.36±5.14 mm3 at 2W follow up, p=0.19). Conclusion(s) This study firstly elucidated very early vascular responses following ultrathin strut BP-SES implantation in STEMI patients, showing early progression of strut coverage and resolution of athero-thrombotic materials. This technology may have a potential to overcome the current generation DESs in this clinical setting. Thrombus, uncovered and malapposed struts Funding Acknowledgement Type of funding source: None

scholarly journals Impact of Thrombus Aspiration on Clinical Outcomes in Korean Patients with ST Elevation Myocardial Infarction

2020 ◽  
Vol 56 (1) ◽  
pp. 36
Author(s):  
Seok-Woo Seong ◽  
Kye Taek Ahn ◽  
Mijoo Kim ◽  
Seon Ah Jin ◽  
Sang Yeub Lee ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Clinical Outcomes ◽  
St Elevation Myocardial Infarction ◽  
Thrombus Aspiration ◽  
Korean Patients ◽  
St Elevation
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