RELATIONSHIP BETWEEN BREAKS IN SEDENTARY BEHAVIOR AND FREE LIVING PHYSICAL ACTIVITY ENERGY EXPENDITURE IN INDIVIDUALS WITH CORONARY ARTERY DISEASE

2018 ◽  
Vol 34 (10) ◽  
pp. S40
Author(s):  
A. Ramadi ◽  
D. Buijs ◽  
R. Haennel
Keyword(s):  
Physical Activity ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Energy Expenditure ◽  
Sedentary Behavior ◽  
Physical Activity Energy Expenditure ◽  
Free Living ◽  
Artery Disease ◽  
Activity Energy

scholarly journals Physical activity, sedentary behavior and risk of coronary artery disease, myocardial infarction and ischemic stroke: a two-sample Mendelian randomization study

2021 ◽  
Author(s):  
Martin Bahls ◽  
Michael F. Leitzmann ◽  
André Karch ◽  
Alexander Teumer ◽  
Marcus Dörr ◽  
...  
Keyword(s):  
Physical Activity ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Ischemic Stroke ◽  
Coronary Artery ◽  
Sedentary Behavior ◽  
Mendelian Randomization ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Artery Disease

Abstract Aims Observational evidence suggests that physical activity (PA) is inversely and sedentarism positively related with cardiovascular disease risk. We performed a two-sample Mendelian randomization (MR) analysis to examine whether genetically predicted PA and sedentary behavior are related to coronary artery disease, myocardial infarction, and ischemic stroke. Methods and results We used single nucleotide polymorphisms (SNPs) associated with self-reported moderate to vigorous PA (n = 17), accelerometer based PA (n = 7) and accelerometer fraction of accelerations > 425 milli-gravities (n = 7) as well as sedentary behavior (n = 6) in the UK Biobank as instrumental variables in a two sample MR approach to assess whether these exposures are related to coronary artery disease and myocardial infarction in the CARDIoGRAMplusC4D genome-wide association study (GWAS) or ischemic stroke in the MEGASTROKE GWAS. The study population included 42,096 cases of coronary artery disease (99,121 controls), 27,509 cases of myocardial infarction (99,121 controls), and 34,217 cases of ischemic stroke (404,630 controls). We found no associations between genetically predicted self-reported moderate to vigorous PA, accelerometer-based PA or accelerometer fraction of accelerations > 425 milli-gravities as well as sedentary behavior with coronary artery disease, myocardial infarction, and ischemic stroke. Conclusions These results do not support a causal relationship between PA and sedentary behavior with risk of coronary artery disease, myocardial infarction, and ischemic stroke. Hence, previous observational studies may have been biased. Graphic abstract

The Actiheart in Adolescents: A Doubly Labelled Water Validation

2012 ◽  
Vol 24 (4) ◽  
pp. 589-602 ◽  
Author(s):  
Nerissa Campbell ◽  
Harry Prapavessis ◽  
Casey Gray ◽  
Erin McGowan ◽  
Elaine Rush ◽  
...  
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Resting Energy Expenditure ◽  
Equation Modeling ◽  
Physical Activity Energy Expenditure ◽  
Limits Of Agreement ◽  
Free Living ◽  
Doubly Labelled Water ◽  
Future Work ◽  
Activity Energy

Background/Objective: This study investigated the validity of the Actiheart device for estimating free-living physical activity energy expenditure (PAEE) in adolescents. Subjects/Methods: Total energy expenditure (TEE) was measured in eighteen Canadian adolescents, aged 15–18 years, by DLW. Physical activity energy expenditure was calculated as 0.9 X TEE minus resting energy expenditure, assuming 10% for the thermic effect of feeding. Participants wore the chest mounted Actiheart device which records simultaneously minute-by-minute acceleration (ACC) and heart rate (HR). Using both children and adult branched equation modeling, derived from laboratory-based activity, PAEE was estimated from the ACC and HR data. Linear regression analyses examined the association between PAEE derived from the Actiheart and DLW method where DLW PAEE served as the dependent variable. Measurement of agreement between the two methods was analyzed using the Bland-Altman procedure. Results: A nonsignificant association was found between the children derived Actiheart and DLW PAEE values (R = .23, R2 = .05, p = .36); whereas a significant association was found between the adult derived Actiheart and DLW PAEE values (R = .53, R2 = .29, p < .05). Both the children and adult equation models lead to overestimations of PAEE by the Actiheart compared with the DLW method, by a mean difference of 31.42 kcal·kg−·d−1 (95% limits of agreement: −45.70 to −17.15 kcal·kg−1·d−1 and 9.80 kcal·kg−1·d−1 (95% limits of agreement: −21.22-1.72 kcal·kg−1·d−1), respectively. Conclusion: There is relatively poor measurement of agreement between the Actiheart and DLW for assessing free-living PAEE in adolescents. Future work should develop group based branched equation models specifically for adolescents to improve the utility of the device in this population.

Energy requirements and physical activity in free-living older women and men: a doubly labeled water study

1998 ◽  
Vol 85 (3) ◽  
pp. 1063-1069 ◽  
Author(s):  
Raymond D. Starling ◽  
Michael J. Toth ◽  
William H. Carpenter ◽  
Dwight E. Matthews ◽  
Eric T. Poehlman
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Energy Expenditure ◽  
Older Women ◽  
Fat Free Mass ◽  
Energy Requirements ◽  
Physical Activity Energy Expenditure ◽  
Doubly Labeled Water ◽  
Free Living ◽  
Activity Energy

Determinants of daily energy needs and physical activity are unknown in free-living elderly. This study examined determinants of daily total energy expenditure (TEE) and free-living physical activity in older women ( n = 51; age = 67 ± 6 yr) and men ( n = 48; age = 70 ± 7 yr) by using doubly labeled water and indirect calorimetry. Using multiple-regression analyses, we predicted TEE by using anthropometric, physiological, and physical activity indexes. Data were collected on resting metabolic rate (RMR), body composition, peak oxygen consumption (V˙o 2 peak), leisure time activity, and plasma thyroid hormone. Data adjusted for body composition were not different between older women and men, respectively (in kcal/day): TEE, 2,306 ± 647 vs. 2,456 ± 666; RMR, 1,463 ± 244 vs. 1,378 ± 249; and physical activity energy expenditure, 612 ± 570 vs. 832 ± 581. In a subgroup of 70 women and men, RMR andV˙o 2 peakexplained approximately two-thirds of the variance in TEE ( R 2 = 0.62; standard error of the estimate = ±348 kcal/day). Crossvalidation of this equation in the remaining 29 women and men was successful, with no difference between predicted and measured TEE (2,364 ± 398 and 2,406 ± 571 kcal/day, respectively). The strongest predictors of physical activity energy expenditure ( P < 0.05) for women and men were V˙o 2 peak( r = 0.43), fat-free mass ( r = 0.39), and body mass ( r = 0.34). In summary, RMR andV˙o 2 peak are important independent predictors of energy requirements in the elderly. Furthermore, cardiovascular fitness and fat-free mass are moderate predictors of physical activity in free-living elderly.

scholarly journals Estimation of Physical Activity Energy Expenditure during Free-Living from Wrist Accelerometry in UK Adults

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0167472 ◽  
Author(s):  
Tom White ◽  
Kate Westgate ◽  
Nicholas J. Wareham ◽  
Soren Brage
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Physical Activity Energy Expenditure ◽  
Free Living ◽  
Activity Energy

Validation of Combined Heart Rate and Movement Sensing to Estimate Free-living Physical Activity Energy Expenditure

2007 ◽  
Vol 39 (Supplement) ◽  
pp. S26
Author(s):  
Soren Brage ◽  
Ulf Ekelund ◽  
Paul W. Franks ◽  
Mark A. Hennings ◽  
Antony Wright ◽  
...  
Keyword(s):  
Physical Activity ◽  
Heart Rate ◽  
Energy Expenditure ◽  
Physical Activity Energy Expenditure ◽  
Free Living ◽  
Activity Energy
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