Autologous Bone Marrow Stem Cell Therapy in Patients With ST-Elevation Myocardial Infarction: A Systematic Review and Meta-analysis

2017 ◽  
Vol 33 (12) ◽  
pp. 1611-1623 ◽  
Author(s):  
Maya M. Jeyaraman ◽  
Rasheda Rabbani ◽  
Leslie Copstein ◽  
Wasan Sulaiman ◽  
Farnaz Farshidfar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Systematic Review ◽  
Bone Marrow ◽  
Stem Cell ◽  
Meta Analysis ◽  
Autologous Bone Marrow ◽  
Bone Marrow Stem Cell ◽  
St Elevation ◽  
Autologous Bone ◽  
Marrow Stem Cell

scholarly journals Combination use of core decompression for osteonecrosis of the femoral head: A systematic review and meta-analysis using Forest and Funnel Plots

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Linghanqing Wang ◽  
XuRong Tian ◽  
Keda Li ◽  
Chunlei Liu
Keyword(s):  
Bone Marrow ◽  
Stem Cell ◽  
Femoral Head ◽  
Meta Analysis ◽  
Core Decompression ◽  
Autologous Bone Marrow ◽  
Bone Marrow Stem Cell ◽  
Femoral Head Necrosis ◽  
Autologous Bone ◽  
Marrow Stem Cell

Problem statement. Core decompression (CD) is a very significant process of dealing in the treatment of femoral head necrosis. And CD combined with bone marrow mesenchymal stem cell transplantation has been widely used in clinical practice, but its effectiveness is controversial. This study is carried out to observe its efficacy and outcomes. Objective. This study evaluated the efficacy and safety of CD combined with bone marrow stem cells in the treatment of femoral head necrosis by systematic review and meta-analysis. Methodology. PubMed, The Cochrane Library, Embase, CNKI, Google Scholar and MEDLINE, etc. databases were searched for clinical randomized controlled trials (RCTs) comparing core decompression combined with autologous bone marrow mesenchymal stem cells versus core decompression alone in the treatment of femoral head necrosis. The retrieval period is from the establishment of each database to May 20, 2021. After literature was extracted and literature quality was evaluated, meta-analysis was conducted by using RevMan5.3 software. Results. A total of 420 osteonecrosis of the femoral head 452 patients' data were collected from all studies. Compared with the core decompression alone group, the CD combined with bone marrow stem cell showed marked reduction in the Visual analog scale (VAS), enhanced Harris hip score (HHS) at 12 months and 24 months, slowed down the progression of the disease, decreased the number of hips conversed to total hip arthroplasty (THA) in the future. Conclusion. Core decompression therapy is a very effective and safe treatment process used for ONFH. Moreover, CD combined autologous bone marrow stem cell transplantation can improve the survival rate of the necrotic head, reduce hip pain and delay the disease progression, the rate of THA postoperatively.

scholarly journals Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis

BMJ ◽  
2014 ◽  
Vol 348 (apr28 1) ◽  
pp. g2688-g2688 ◽  
Author(s):  
A. N. Nowbar ◽  
M. Mielewczik ◽  
M. Karavassilis ◽  
H.-M. Dehbi ◽  
M. J. Shun-Shin ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stem Cell ◽  
Ejection Fraction ◽  
Meta Analysis ◽  
Autologous Bone Marrow ◽  
Bone Marrow Stem Cell ◽  
Weighted Regression ◽  
Autologous Bone ◽  
Marrow Stem Cell
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