PULMONARY ARTERY WALL THICKNESS IN CHILDREN WITH FONTAN PHYSIOLOGY – AN OPTICAL COHERENCE TOMOGRAPHY CASE CONTROL STUDY

2017 ◽  
Vol 33 (10) ◽  
pp. S6-S7
Author(s):  
E. McGovern ◽  
C. Voss ◽  
S. Duncombe ◽  
M. Hosking ◽  
K. Harris
Keyword(s):  
Optical Coherence Tomography ◽  
Pulmonary Artery ◽  
Wall Thickness ◽  
Case Control Study ◽  
Case Control ◽  
Optical Coherence ◽  
Artery Wall ◽  
Fontan Physiology ◽  
Control Study

Pulmonary artery wall thickness in children with Fontan physiology: an optical coherence tomography case control study

2019 ◽  
Vol 29 (4) ◽  
pp. 524-527
Author(s):  
Eimear McGovern ◽  
Christine Voss ◽  
Nathan W. Brunner ◽  
Stephanie Duncombe ◽  
Kevin C. Harris ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Pulmonary Artery ◽  
Wall Thickness ◽  
Structural Changes ◽  
Pulmonary Arteries ◽  
Causative Factor ◽  
Optical Coherence ◽  
Artery Wall ◽  
Cross Sectional ◽  
Fontan Patients

AbstractIntroduction:Failure of the Fontan circulation is not a well-understood clinical phenomena.For some patients, a gradual increase in pulmonary vascular resistance (PVR) and structural changes in the pulmonary artery may be an important causative factor. To further investigate this issue, we employed optical coherence tomography (OCT) to evaluate structural changes within the pulmonary arteries of Fontan patients and compared to those with a normal pulmonary circulation.Materials and Methods:Pulmonary artery OCT was performed, without complications, in 12 Fontan and 11 control patients. Wall thickness and wall:vessel cross-sectional area (CSA) ratio were calculated after image acquisition, using digital planimetry.Results:There was no difference in wall thickness between both groups. Median wall thickness for Fontan patients was 0.12 mm (IQR, 0.10–0.14) and for controls was 0.11 mm (IQR, 0.10–0.12; p = 0.62). Wall:vessel CSA ratio for Fontan patients was 0.13 (IQR, 0.12–0.16) and for controls was 0.13 (IQR, 0.11–0.15) (p = 0.73). There was no association between wall thickness and ventricle morphology, age at catheterisation, age at Fontan, years since Fontan completion, pulmonary artery pressure, and PVR. The vessel media was more readily visualised in control patients.Discussion:OCT of the pulmonary arteries in Fontan patients is safe and feasible. Our OCT findings suggest that during childhood, pulmonary artery wall dimensions are normal in Fontan children with reassuring hemodynamics. Further evaluation of Fontan patients with abnormal hemodynamics and serial evaluation into adulthood are required to conclude on the utility of OCT for identifying early pulmonary artery structural changes.

scholarly journals Nerve fiber layer in glaucomatous hemifield loss: a case-control study with time- and spectral-domain optical coherence tomography

2012 ◽  
Vol 75 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Alexandre Soares Castro Reis ◽  
Kallene Summer Moreira Vidal ◽  
André Carvalho Kreuz ◽  
Mario Luiz Ribeiro Monteiro ◽  
Marcelo Teixeira Nicolela ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Case Control Study ◽  
Case Control ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Control Study ◽  
Hemifield Loss
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