PROGNOSTIC VALUE OF T-WAVE INVERSION ON THE PRESENTING VERSUS FOLLOW-UP ECG IN NON-ST ELEVATION ACUTE CORONARY SYNDROMES

2015 ◽  
Vol 31 (10) ◽  
pp. S284-S285
Author(s):  
B. Sarak ◽  
S.G. Goodman ◽  
R.T. Yan ◽  
M.K. Tan ◽  
P.G. Steg ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
T Wave ◽  
Wave Inversion ◽  
Coronary Syndromes ◽  
St Elevation

scholarly journals DOES GRACE SCORE INCREMENT PROGNOSTIC ASSESSMENT AFTER ANGIOGRAPHY IN ACUTE CORONARY SYNDROMES?

2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Guilherme Garcia ◽  
Rafael Freitas ◽  
Felipe Kalil ◽  
Felipe Ferreira ◽  
André Silva ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Coronary Anatomy ◽  
Prognostic Assessment ◽  
C Statistic ◽  
Angiographic Data ◽  
Coronary Syndromes ◽  
St Elevation ◽  
Anatomical Information ◽  
Grace Score

Rational: The GRACE Score assessed at admission predicts mortality in patients with non-ST elevation acute coronary syndromes (ACS). However, once coronary anatomy is assessed, it is not known whether this score increments prognostic assessment.  Objective: To test the hypothesis that the GRACE Score adds prognostic value to coronary anatomy in patients with ACS. Methods: Prospective cohort, including patients with ACS who underwent coronary angiography while admitted to the hospital. Anatomical extension of coronary disease was characterized by the Duke Jeopardy score (DJS) and the number diseased artery (NDA). The primary end-point was the composite of death, non-fatal MI or refractory unstable angina.  Results: 112 patients enrolled, aged 70 ± 12, 14% incidence of cardiovascular events. C-statistics for GRACE was 0.68 (95%CI=0.53-0.84), for DJS was 0.78 (95%CI=0.67-0.9) and for NAD was 0.74 (95%CI=0.61-0.88). Logistic regression analysis demonstrated independent predictive value of GRACE in relation to anatomical information. However, when this Score was added to DJS or NDA, no improving in c-statistic was observed: DJS-GRACE had a c-statistics of 0.78 (95%CI=0.64–0.92) and NAD-GRACE of 0.76 (95%CI=0.60–0.92).  Conclusion: The GRACE score does not add prognostic value to angiographic data in patients with ACS.

Does acute hyperglycemia add prognostic value to the GRACE score in individuals with non-ST elevation acute coronary syndromes?

2009 ◽  
Vol 410 (1-2) ◽  
pp. 74-78 ◽  
Author(s):  
Luis C.L. Correia ◽  
Mário S. Rocha ◽  
Ana P. Bittencourt ◽  
Rafael Freitas ◽  
Alexandre C. Souza ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Acute Hyperglycemia ◽  
Coronary Syndromes ◽  
St Elevation ◽  
Grace Score

Dynamic thiol/disulphide homeostasis and its prognostic value in patients with non-ST elevation-acute coronary syndromes

2017 ◽  
pp. 426-432
Author(s):  
Serkan Sivri ◽  
Hacı Ahmet Kasapkara ◽  
Melike Polat ◽  
Yakup Alsancak ◽  
Tahir Durmaz ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Coronary Syndromes ◽  
St Elevation

scholarly journals Prognostic value of cytokines and chemokines in addition to the GRACE Score in non-ST-elevation acute coronary syndromes

2010 ◽  
Vol 411 (7-8) ◽  
pp. 540-545 ◽  
Author(s):  
Luis C.L. Correia ◽  
Bruno B. Andrade ◽  
Valéria M. Borges ◽  
Jorge Clarêncio ◽  
Ana P. Bittencourt ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Cytokines And Chemokines ◽  
Coronary Syndromes ◽  
St Elevation ◽  
Grace Score

scholarly journals HEMOGLOBIN LEVELS AT ADMISSION ADD PROGNOSTIC VALUE TO THE GRACE SCORE IN NON-ST ELEVATION ACUTE CORONARY SYNDROMES

2010 ◽  
Vol 55 (10) ◽  
pp. A115.E1075
Author(s):  
Luis Correia ◽  
Jamile Leal ◽  
Maria C. Almeida ◽  
Alexandre C. Souza ◽  
Ana P. Bittencourt ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Coronary Syndromes ◽  
St Elevation ◽  
Grace Score

scholarly journals MODERN METHODS TO DIFFERENTIATE BETWEEN CHEST PAIN AND CARDIAC ISCHEMIA

2020 ◽  
Vol 49 (06) ◽  
pp. 43-43
Author(s):  
Giorgi Javakhishvili ◽  
Rusudan Sujashvili
Keyword(s):  
Acute Coronary Syndrome ◽  
Acute Coronary Syndromes ◽  
St Segment Elevation ◽  
Coronary Syndrome ◽  
T Wave ◽  
Fibrous Cap ◽  
St Segment ◽  
Coronary Syndromes ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome

Acute coronary syndrome (ACS) is a group of conditions which often present with similar signs and symptoms while having different outcomes and complications. Therefore it is essential to differentiate between them as soon as possible and provide appropriate management. Acute coronary syndromes are classified into two categories: STE-ACS (ST segment Elevation Acute Coronary Syndrome) and NSTE-ACS (Non ST segment Elevation Acute Coronary Syndrome). STE-ACS stands for ST Elevation Acute Coronary Syndrome all of which demonstrate significant ST elevations on ECG due to complete blockage of artery by thrombus, while NSTE-ACS is due to partial occlusion of artery which exhibit ST segment depression and/or T wave inversions. Patients with NSTE-ACS who do not develop infarction are diagnosed with unstable angina, which itself is a precursor of myocardial infarction. Acute coronary syndromes are considered multifactorial and risk factors most commonly associated with development of acute coronary syndromes include: hypertension, smoking, diabetes, obesity, sedentary life-style, hereditary conditions etc. Chronic stress to the coronary endothelium eventually leads to inflammation and atherosclerotic plaque formation. Plaque at some point with additional stress will rupture and trigger thrombus formation. Probability of plaque rupture depends on its composition: stable plaques contain small fatty core and thick fibrous cap, unstable plaque have larger fatty cores and thin fibrous cap. Patients with acute coronary syndromes present with chest pain and/or discomfort and may experience tightness and pressure sensation; pain may radiate to left or both arms, jaw, back or stomach, sweating, dyspnea and dizziness are also common complaints. Whenever we suspect ACS first diagnostic tests is always ECG (Electrocardiography). If ST segment is persistently elevated STEMI (ST Elevation Myocardial Infarction) can be diagnosed and reperfusion therapy is indicated; but if ST segment is depressed and/or T wave inversion is present laboratory tests are necessary for diagnosis. Cardiac biomarkers mainly used in the clinic are Troponins and CK-MB (Creatine Kinase MB), yet LDH (lactate dehydrogenase), B-type natriuretic peptide and C-reactive protein can be used additionally. Several studies have been conducted in hopes to find other myocardial markers useful for diagnosis of ACS, one of which tested candidate biomarkers such as hFABP (Heart-type fatty acid binding protein), GPBB (Glycogen Phosphorylase Isoenzyme BB), S100, PAPP-A (Pregnancy-associated plasma protein A), TNF (Tumor Necrosis Factor), IL6 (Interleukin 6), IL18 (Interleukin 18), CD40 (Cluster of differentiation 40) ligand, MPO (Myeloperoxidase), MMP9 (Matrix metallopeptidase 9), cell-adhesion molecules, oxidized LDL (Low Density Lipoprotein), glutathione, homocysteine, fibrinogen, and D-dimer, procalcitonin. The idea of this study was to estimate usefulness of combining enzymatic markers with nonenzymatic ones in the clinical settings.

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