362 Left Atrial Appendage Closure With the Amplatzer Cardiac Plug: Impact of Shape and Device Sizing on Follow-Up Leaks

2012 ◽  
Vol 28 (5) ◽  
pp. S234
Author(s):  
X. Freixa ◽  
A. Tzikas ◽  
A. Sobrino ◽  
J. Chan ◽  
A. Basmadjian ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure

Evaluating long-term outcomes of left atrial appendage occlusion: the results of a prospective single-center registry

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
M Maarse ◽  
L Wintgens ◽  
E Aarnink ◽  
M Huijboom ◽  
B Abeln ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Major Bleeding ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure ◽  
Left Atrial Appendage Occlusion ◽  
Long Term Follow Up

Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): This work was supported by an unrestricted grant from Boston Scientific. Boston Scientific was not involved in the design/conduct of the study, data collection/analysis and interpretation of the data and preparation of the manuscript. Background Percutaneous left atrial appendage occlusion is an emerging alternative to anticoagulation in the prevention for stroke in patients with atrial fibrillation, especially in patients with a contra-indication for oral anticoagulation therapy. Long-term results on the efficacy and safety of this treatment remain scarce. Methods In this single-center prospective registry, data of all consecutive patients that underwent percutaneous left atrial appendage closure between 2009 and 2019 were collected. Patients with successful left atrial appendage closure (peri-device leakage ≤5mm) and at least one year of follow-up data were analyzed. The occurrence of thrombo-embolic events (ischemic stroke, TIA and systemic embolism), major bleeding events (BARC >2) and anticoagulation use during long-term follow-up were evaluated. Results A total of 192 patients after left atrial appendage occlusion were included (61 % male, age 69.0 ± 8.4 years, CHA2DS2-VASc 4.0[3.0-5.0], HAS-BLED 3.0[2.0-3.25]) with a mean follow-up duration of 5.7 ± 2.8 years (in total 1087 patient-years). During follow-up 36 patients (19%) died. 49 thrombo-embolic complications were observed in 38 patients. The ischemic stroke rate was 1.9 events per 100 patient-years, accounting for a 70% reduction compared to CHA2DS2-VASc predicted rate. Device-related thrombus (DRT) occurred in 5 patients (2.6%), 3 were observed during routine follow-up and were not associated with thrombo-embolic complications. The other 2 DRT were observed in patients presenting with ischemic stroke more than 3 years after device implantation. Furthermore, 38 non-procedural major bleeding complications occurred in 19 patients, resulting in 3.5 events per 100-patients years, accounting for a reduction of 43% compared to estimated bleeding rates under OAC use. At the end of the study 71% of all patients were on single antiplatelet or no antiplatelet/anticoagulation treatment at all. Conclusions During long-term follow-up thrombo-embolic event rates and non-procedural major bleeding rates were consistently low (ischemic stroke rate reduction 70% and non-procedural major bleeding rate reduction 40% compared to predicted rates). These results confirm the efficacy of left atrial appendage occlusion. Abstract Figure. Ischemic stroke rates

P395Mid-term follow-up and anticoagulation management after left atrial appendage closure

EP Europace ◽  
2018 ◽  
Vol 20 (suppl_1) ◽  
pp. i71-i71
Author(s):  
P Jacon ◽  
S Venier ◽  
F Dugenet ◽  
N Dayal ◽  
A Carrabelli ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure ◽  
Anticoagulation Management

scholarly journals TCT-26 Long-Term Event Rates for Left Atrial Appendage Closure with WATCHMAN: PROTECT AF 5 Year and PREVAIL 3 Year Follow-up

2016 ◽  
Vol 68 (18) ◽  
pp. B11 ◽  
Author(s):  
Vivek Reddy ◽  
Matthew Price ◽  
Miguel valderrabano ◽  
Jose Sanchez ◽  
Shephal Doshi ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure ◽  
Event Rates

scholarly journals TCT-689 Left atrial appendage closure with a novel device: initial experience and short-term follow-up from a single center

2017 ◽  
Vol 70 (18) ◽  
pp. B256 ◽  
Author(s):  
Paolo Pagnotta ◽  
Mauro Chiarito ◽  
Elton Pllaha ◽  
Riccardo Mantovani ◽  
Giulio Stefanini ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Initial Experience ◽  
Single Center ◽  
Left Atrial Appendage Closure ◽  
Short Term ◽  
Novel Device

Follow-up imaging after left atrial appendage closure

Heart Rhythm ◽  
2020 ◽  
Vol 17 (11) ◽  
pp. 1848-1855
Author(s):  
Kenji Kuroki ◽  
Shephal K. Doshi ◽  
William Whang ◽  
Sarina Vanderzee ◽  
Crystal B. Ducharme ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure

Thromboembolism after electrical isolation of the left atrial appendage: a new indication for interventional closure?

EP Europace ◽  
2019 ◽  
Vol 21 (10) ◽  
pp. 1502-1508 ◽  
Author(s):  
Niklas Zender ◽  
Felix K Weise ◽  
Stefano Bordignon ◽  
Eva Herrmann ◽  
Athanasios Konstantinou ◽  
...  
Keyword(s):  
Primary Endpoint ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Thromboembolic Complications ◽  
Left Atrial Appendage Closure ◽  
Electrical Isolation ◽  
Secondary Endpoints ◽  
Event Rates

Abstract Aims Left atrial appendage electrical isolation (LAAI) may improve the rhythm outcome in selected patients with atrial fibrillation (AF). Controversy exists if LAAI is associated with an increased rate of thromboembolic complications. We sought to assess the feasibility, efficacy, and safety of interventional left atrial appendage closure (LAAC) in comparison to oral anticoagulation (OAC) after electrical LAAI. Methods and results Weeks after index LAAI using the cryoballoon or a linear maze like ablation strategy patients’ left atrial appendage was invasively remapped. In case of persistent LAAI, LAAC was performed. Patients who refused invasive remapping continued OAC. The primary endpoint was composed of any stroke or systemic embolism (SE) and the occurrence of intracardiac thrombus. Secondary endpoints included stroke/SE, major bleeding, and all-cause death. Of 166 patients (51% female; mean age 70 ± 8 years; mean CHAD2S2VASc score 3.4 ± 1.8) after LAAI, 94 patients received LAAC (LAAC group) and 72 continued OAC (no LAAC). After LAAC, 83% of patients received dual antiplatelet therapy for 6 weeks and aspirin thereafter. During a mean follow-up of 778 ± 630 days, 5 and 11 primary endpoint events were observed in the LAAC and no LAAC group, respectively [hazard ratio (HR) 0.27, 95% confidence interval (CI) 0.10–0.75; P = 0.010]. The calculated annual thromboembolic event rates were 6.9% (no LAAC) and 2.3% (LAAC), respectively. Left atrial appendage closure significantly reduced the incidence of stroke and SE (HR 0.31, CI 0.1–0.98; P = 0.04). Conclusion After electrical LAAI for rhythm control in AF patients, interventional LAAC was associated with fewer thromboembolic complications when compared with OAC.

Long-term transesophageal echocardiography follow-up after percutaneous left atrial appendage closure

Heart Rhythm ◽  
2020 ◽  
Vol 17 (5) ◽  
pp. 728-733 ◽  
Author(s):  
Stephan Staubach ◽  
Leonhard Schlatterbeck ◽  
Moritz Mörtl ◽  
Henning Strohm ◽  
Petra Hoppmann ◽  
...  
Keyword(s):  
Transesophageal Echocardiography ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure

Prevention of stroke by percutaneous left atrial appendage closure: Short term follow-up

2010 ◽  
Vol 142 (2) ◽  
pp. 195-196 ◽  
Author(s):  
Pieter De Meester ◽  
Vincent Thijs ◽  
Kristien Van Deyk ◽  
Werner Budts
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Left Atrial Appendage Closure ◽  
Short Term
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