454 Long-term renal effects of switching cardiac transplant patients with cni-induced renal dysfunction to sirolimus: a single center prospective study

2011 ◽  
Vol 27 (5) ◽  
pp. S226-S227
Author(s):  
M. White ◽  
A. Boucher ◽  
R. Dandavino ◽  
A. Fortier ◽  
G.B. Pelletier ◽  
...  
Keyword(s):  
Prospective Study ◽  
Renal Dysfunction ◽  
Cardiac Transplant ◽  
Single Center ◽  
Renal Effects ◽  
Transplant Patients

Long-Term Study of Steroid Avoidance in Renal Transplant Patients: A Single-Center Experience

2015 ◽  
Vol 47 (4) ◽  
pp. 1099-1104 ◽  
Author(s):  
A.M. Nagib ◽  
M.H. Abbas ◽  
M.M. Abu-Elmagd ◽  
A.A.E.F. Denewar ◽  
A.H. Neamatalla ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Single Center ◽  
Term Study ◽  
Transplant Patients ◽  
Single Center Experience ◽  
Long Term Study ◽  
Renal Transplant Patients ◽  
Steroid Avoidance

Immediate and long-term results of total mesorectumectomy for rectal cancer. A single-center prospective study

2021 ◽  
Vol 10 (1) ◽  
pp. 5
Author(s):  
D.V. Sidorov ◽  
A.A. Troitsky ◽  
M.V. Lozhkin ◽  
N.A. Grishin ◽  
I.V. Stepanyuk
Keyword(s):  
Rectal Cancer ◽  
Prospective Study ◽  
Long Term Results ◽  
Single Center

Abstract 540: Correlation of Improved Cholesterol Efflux Capacity of High Density Lipoprotein With Survival and Allograft Vasculopathy in Cardiac Transplant Recipients

2015 ◽  
Vol 35 (suppl_1) ◽  
Author(s):  
Ali Javaheri ◽  
Payman Zamani ◽  
Maria Molina ◽  
Amrith Rodrigues ◽  
Susan Chambers ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cholesterol Efflux ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Cardiac Transplant ◽  
Transplant Recipients ◽  
Single Center ◽  
Allograft Vasculopathy ◽  
Cholesterol Efflux Capacity ◽  
Transplant Patients

Background: Coronary allograft vasculopathy (CAV) is an important cause of mortality after cardiac transplantation. High density lipoprotein (HDL) cholesterol efflux capacity has been inversely associated with coronary artery disease and is impaired in cardiac transplant recipients. We performed a single center case-cohort study to test the hypothesis that reduced efflux capacity is a risk factor for mortality and a second, multi-center retrospective study to test if efflux capacity is associated with CAV progression. Methods: We designed a single center case-cohort study in which we identified cardiac transplant patients who died between 2009-2012 (cases, n=34) and controls as cardiac transplant patients who were alive as of the fourth quarter of 2013 (n=57). Efflux capacity was measured by incubating apolipoprotein B-depleted serum with macrophages in a validated ex vivo system. In a second study, we utilized pre-transplant samples from the Clinical Trials in Organ Transplantation 5 (CTOT5) study to determine the association between ATP-binding-cassette (ABC) A1-dependent cholesterol efflux and CAV progression at 1 year. Results: In our single center study, the average time from transplant to study entry was well-matched between cases and controls (7.6±1.0 vs 7.7±0.8 years, respectively, p=0.48). Multivariable Cox proportional hazard ratios demonstrated that higher levels of HDL cholesterol efflux capacity were associated with survival (HR 0.61, 95% CI 0.43-0.85), even after adjustment for HDL cholesterol mass. To determine whether excess mortality observed in subjects with reduced efflux could be attributable to CAV progression, we tested the relationship between intravascular ultrasound (IVUS) progression of CAV and cholesterol efflux capacity using linear regression. ABCA1-dependent efflux and IVUS progression were significantly associated (β = -0.90, 95% CI [-1.73 - -0.07], p = 0.037, R2 = 0.37). Conclusion: Reduced efflux capacity is an important mediator of CAV progression and mortality in cardiac transplant recipients. This finding suggests that interventions to increase HDL cholesterol efflux capacity may provide clinical benefit in cardiac transplant recipients.

scholarly journals Successful long-term remission through tapering tocilizumab infusions: a single-center prospective study

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Chayma Ladhari ◽  
Pierre Le Blay ◽  
Thierry Vincent ◽  
Ahmed Larbi ◽  
Emma Rubenstein ◽  
...  
Keyword(s):  
Prospective Study ◽  
Single Center

Long-term follow-up of cardiac transplant patients

1970 ◽  
Vol 25 (1) ◽  
pp. 88-89
Author(s):  
David A. Clark ◽  
Edward B. Stinson ◽  
John S. Schroeder ◽  
Norman E. Shumway ◽  
Donald C. Harrison
Keyword(s):  
Cardiac Transplant ◽  
Transplant Patients ◽  
Long Term Follow Up

THE IMPACT OF AZATHIOPRINE ON CHRONIC VIRAL HEPATITIS IN RENAL TRANSPLANTATION: A LONG-TERM, SINGLE-CENTER, PROSPECTIVE STUDY ON AZATHIOPRINE WITHDRAWAL1

1999 ◽  
Vol 68 (7) ◽  
pp. 976-980 ◽  
Author(s):  
Elias David-Neto ◽  
Jo??o Americo da Fonseca ◽  
Flavio Jota de Paula ◽  
William Carlos Nahas ◽  
Emil Sabbaga ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Prospective Study ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Single Center ◽  
The Impact

Prognostic Significance of Heart Rate and its Long-term Trend in Cardiac Transplant Patients

2015 ◽  
Vol 68 (11) ◽  
pp. 943-950 ◽  
Author(s):  
Eduardo Barge-Caballero ◽  
Jesús Jiménez-López ◽  
Sergio Chávez-Leal ◽  
Gonzalo Barge-Caballero ◽  
María Jesús Paniagua-Martin ◽  
...  
Keyword(s):  
Heart Rate ◽  
Prognostic Significance ◽  
Cardiac Transplant ◽  
Term Trend ◽  
Transplant Patients ◽  
Long Term Trend
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