694 Characterization and functional implications of heart rate increase at the onset of exercise testing and heart rate recovery in patients with advanced heart failure

2011 ◽  
Vol 27 (5) ◽  
pp. S316-S317
Author(s):  
M. White ◽  
J. Myers ◽  
M.C. Guertin ◽  
M. Cossette ◽  
A. Ducharme ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Exercise Testing ◽  
Rate Increase ◽  
Heart Rate Recovery ◽  
Advanced Heart Failure ◽  
Heart Rate Increase ◽  
Functional Implications

scholarly journals Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Christine Sailer ◽  
Hannah Edelmann ◽  
Cullen Buchanan ◽  
Pedro Giro ◽  
Matthew Babcock ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Left Ventricular ◽  
Advanced Heart Failure ◽  
Ventricular Assist Devices ◽  
Left Ventricular Assist Devices ◽  
Baroreceptor Sensitivity ◽  
Cardiopulmonary Exercise

Background: Continuous-flow (CF) left ventricular assist devices (LVADs) improve outcomes for patients with advanced heart failure (HF). However, the lack of a physiological pulse predisposes to side-effects including uncontrolled blood pressure (BP), and there are little data regarding the impact of CF-LVADs on BP regulation. Methods: Twelve patients (10 males, 60±11 years) with advanced heart failure completed hemodynamic assessment 2.7±4.1 months before, and 4.3±1.3 months following CF-LVAD implantation. Heart rate and systolic BP via arterial catheterization were monitored during Valsalva maneuver, spontaneous breathing, and a 0.05 Hz repetitive squat-stand maneuver to characterize cardiac baroreceptor sensitivity. Plasma norepinephrine levels were assessed during head-up tilt at supine, 30 o and 60 o . Heart rate and BP were monitored during cardiopulmonary exercise testing. Results: Cardiac baroreceptor sensitivity, determined by Valsalva as well as Fourier transformation and transfer function gain of Heart rate and systolic BP during spontaneous breathing and squat-stand maneuver, was impaired before and following LVAD implantation. Norepinephrine levels were markedly elevated pre-LVAD and improved—but remained elevated post-LVAD (supine norepinephrine pre-LVAD versus post-LVAD: 654±437 versus 323±164 pg/mL). BP increased during cardiopulmonary exercise testing post-LVAD, but the magnitude of change was modest and comparable to the changes observed during the pre-LVAD cardiopulmonary exercise testing. Conclusions: Among patients with advanced heart failure with reduced ejection fraction, CF-LVAD implantation is associated with modest improvements in autonomic tone, but persistent reductions in cardiac baroreceptor sensitivity. Exercise-induced increases in BP are blunted. These findings shed new light on mechanisms for adverse events such as stroke, and persistent reductions in functional capacity, among patients supported by CF-LVADs. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03078972.

scholarly journals Abnormal Heart Rate Recovery Immediately After Cardiopulmonary Exercise Testing in Heart Failure Patients

2006 ◽  
Vol 47 (3) ◽  
pp. 431-440 ◽  
Author(s):  
Tuba Bilsel ◽  
Sait Terzi ◽  
Tamer Akbulut ◽  
Nurten Sayar ◽  
Gultekin Hobikoglu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Exercise Testing ◽  
Heart Rate Recovery ◽  
Cardiopulmonary Exercise Testing ◽  
Heart Failure Patients ◽  
Cardiopulmonary Exercise

scholarly journals Prognostic Value of Heart Rate Increase at Onset of Exercise Testing

Circulation ◽  
2007 ◽  
Vol 115 (4) ◽  
pp. 468-474 ◽  
Author(s):  
Nicholas J. Leeper ◽  
Frederick E. Dewey ◽  
Euan A. Ashley ◽  
Marcus Sandri ◽  
Swee Yaw Tan ◽  
...  
Keyword(s):  
Heart Rate ◽  
Exercise Testing ◽  
Prognostic Value ◽  
Rate Increase ◽  
Heart Rate Increase

QT dynamicity is increased in the conscious rabbit with heart failure during heart rate increase

2011 ◽  
Vol 44 (2) ◽  
pp. e28-e29
Author(s):  
Mari Watanabe ◽  
Noriko Niwa ◽  
Tomofumi Kimotsuki ◽  
Martin Hicks ◽  
Michael Dunne ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Rate Increase ◽  
Heart Rate Increase ◽  
Conscious Rabbit

Heart Rate Increase from Rest to Maximal Exercise Is Prognostically Significant in Beta-Blocked Heart Failure Patients

2007 ◽  
Vol 13 (6) ◽  
pp. S158
Author(s):  
Marco Guazzi ◽  
Jonathan Myers ◽  
Mary Ann Peberdy ◽  
Daniel Bensimhon ◽  
Paul Chase ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Rate Increase ◽  
Maximal Exercise ◽  
Heart Rate Increase ◽  
Heart Failure Patients
Sign in / Sign up

Export Citation Format

Share Document