201 Efficacy and safety of protected endovascular treatment in high risk patients with severe carotid stentosis (early and long term follow-up)

2011 ◽  
Vol 27 (5) ◽  
pp. S133
Author(s):  
M. Ghasemi ◽  
B. Heidari Agdam ◽  
A. Kaboli ◽  
R. Abulfazli
Keyword(s):  
High Risk ◽  
Endovascular Treatment ◽  
Efficacy And Safety ◽  
High Risk Patients ◽  
Long Term Follow Up ◽  
Risk Patients

scholarly journals Increased serum IL-6 is predictive of long-term cardiovascular events in high-risk patients submitted to coronary angiography: an observational study.

2021 ◽  
Author(s):  
Márcio Mossmann ◽  
Marco Vugman Wainstein ◽  
Stéfani Mariani ◽  
Guilherme Pinheiro Machado ◽  
Gustavo Neves Araujo ◽  
...  
Keyword(s):  
High Risk ◽  
Coronary Angiography ◽  
Observational Study ◽  
Cardiovascular Events ◽  
Primary Outcome ◽  
High Risk Patients ◽  
Long Term Follow Up ◽  
Risk Patients

Abstract BACKGROUND Interleukin-6 (IL-6) is an inflammation-related cytokine associated with an elevated risk of cardiovascular events. In a previous study, we demonstrated that increased IL-6 was predictive of sub-clinical atherosclerotic coronary disease in intermediate-risk patients undergoing coronary angiography. In the present study, we investigated whether increased serum IL-6 is predictive of cardiovascular events in high-risk patients. METHODS In this observational study, consecutive patients referred for elective coronary angiography due to stable chest pain/myocardial ischemia had IL-6 measured immediately before the procedure. Long-term follow-up was performed by phone call or e-mail, and their clinical registries were revised. The primary outcome was a composite of new myocardial infarction, new ischemic stroke, hospitalization due to heart failure, new coronary revascularization, cardiovascular death, and death due to all causes. RESULTS From the 141 selected patients, 100 completed the IL-6 analysis and were followed for a mean of 5.5 years. The median age was 61.1 years, 44% were men, and 61% had type-2 diabetes. The median overall time-to-event for the primary outcome was 297 weeks (95% confidence interval [CI] = 266.95–327.16). A receiver operator characteristic curve defined the best cut-off value of baseline serum IL-6 (0.44 pg/mL) with sensitivity (84.37%) and specificity (38.24%) to define two groups. High IL-6 level was moderately predictive of cardiovascular events. ( p for interaction = 0.015) (hazard ratio = 2.81; 95% CI = 1.38–5.72, p=0.01). The subgroup analysis did not find interactions between patients with or without diabetes, obesity, or hypertension. CONCLUSION This preliminary study indicates that, in high-risk symptomatic patients undergoing elective coronary angiography, increased pre-procedure serum levels of IL-6 predicted long-term cardiovascular outcomes. These results were similar irrespective of diabetes, hypertension, or obesity status. IL-6 must be studied in larger long-term follow-up studies as a potential tool to re-classify patients with increased cardiovascular risk.

C134 Hinman-Allen syndrome: Is it safe to perform augmentation in high risk patients? A comparative study with long term follow-up

2009 ◽  
Vol 8 (8) ◽  
pp. 702
Author(s):  
M.S. Silay ◽  
O. Tanriverdi ◽  
T. Karatag ◽  
M. Aydın ◽  
M. Kadihasanoglu ◽  
...  
Keyword(s):  
High Risk ◽  
Comparative Study ◽  
High Risk Patients ◽  
Long Term Follow Up ◽  
Risk Patients

Long-Term Follow-Up of High-Risk Patients in the National Emphysema Treatment Trial

2014 ◽  
Vol 98 (5) ◽  
pp. 1782-1789 ◽  
Author(s):  
Robert M. Kaplan ◽  
Qiankun Sun ◽  
Keith S. Naunheim ◽  
Andrew L. Ries
Keyword(s):  
High Risk ◽  
Treatment Trial ◽  
High Risk Patients ◽  
Long Term Follow Up ◽  
Risk Patients ◽  
National Emphysema Treatment Trial

Long-term Follow-up After Percutaneous Treatment of the Unprotected Left Main Stenosis in High Risk Patients Not Suitable for Bypass Surgery

2012 ◽  
Vol 65 (6) ◽  
pp. 530-537
Author(s):  
Joan Antoni Gómez-Hospital ◽  
Josep Gomez-Lara ◽  
Juan Rondan ◽  
Silvia Homs ◽  
Iñigo Lozano Martínez-Luengas ◽  
...  
Keyword(s):  
High Risk ◽  
Bypass Surgery ◽  
Percutaneous Treatment ◽  
Left Main ◽  
Left Main Stenosis ◽  
High Risk Patients ◽  
Long Term Follow Up ◽  
Risk Patients
Sign in / Sign up

Export Citation Format

Share Document