Computational approaches to design a molecular imprinted polymer for high selective extraction of 3,4-methylenedioxymethamphetamine from plasma

2011 ◽  
Vol 1218 (43) ◽  
pp. 7739-7747 ◽  
Author(s):  
Farhad Ahmadi ◽  
Jafar Ahmadi ◽  
Mehdi Rahimi-Nasrabadi
Keyword(s):  
Selective Extraction ◽  
Molecular Imprinted Polymer ◽  
Imprinted Polymer ◽  
Computational Approaches

scholarly journals A Molecularly Imprinted Polymer for Selective Extraction of Phenolic Acids from Human Urine

2021 ◽  
Vol 11 (4) ◽  
pp. 1577
Author(s):  
Marco Mora-Granados ◽  
David González-Gómez ◽  
Jin Su Jeong ◽  
Alejandrina Gallego-Picó
Keyword(s):  
Phenolic Acids ◽  
Molecularly Imprinted Polymer ◽  
Human Urine ◽  
Limit Of Detection ◽  
Ph Dependence ◽  
Selective Extraction ◽  
Screening Methods ◽  
Specific Method ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Studies for monitoring the bioavailability of dietary flavonoid compounds generate great interest. Among them, low-molecular-weight phenolic acids, secondary metabolites present in colonic catabolism and urinary excretion, have been proposed as biomarkers of polyphenol intake. Using 4-hydroxyphenylacetic acid as a template, a molecularly imprinted polymer (MIP) was synthesized for selective extraction of these hydroxylated metabolites from human urine samples and posterior analysis in an HPLC-DAD-MS system. Polymers were characterized by Scanning electron microscopy (SEM), Attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), Brunauer-Emmett-Teller (BET) method, and binding experiments. MIP presents specific recognition ability for template and analogues molecules. This capacity of recognition and the pH dependence of the binding strength was also studied. The method was validated over a concentration range of 0.25–40 mg/L, r2 > 0.995. In the optimized conditions, the recovery value was 94% with RSD 1.2%. The Limit of Detection (LOD) and Limit of Quantification (LOQ) were 1.22 and 3.69 mg/L, respectively. In our knowledge, it is the first time that this methodology is applied to analyze urinary catabolites of the polyphenol compound and to provide a specific method and simple analysis alternative. The selective extraction of these metabolites improves the application and results obtained by other less sensitive analysis methods than the validation method. It also facilitates the development of new screening methods.

Molecular imprinted polymer to remove tetracycline from aqueous solutions

2015 ◽  
Vol 203 ◽  
pp. 32-40 ◽  
Author(s):  
M. Sánchez-Polo ◽  
I. Velo-Gala ◽  
Jesús J. López-Peñalver ◽  
J. Rivera-Utrilla
Keyword(s):  
Aqueous Solutions ◽  
Molecular Imprinted Polymer ◽  
Imprinted Polymer

Thermodinamic study of a magnetic molecular imprinted polymer for removal of nitrogenous pollutant from gasoline

Fuel ◽  
2017 ◽  
Vol 210 ◽  
pp. 380-389 ◽  
Author(s):  
Liz Nayibe Martínez Saavedra ◽  
Bruno Eduardo Lobo Baeta ◽  
Márcio César Pereira ◽  
Luiz Carlos Alves de Oliveira ◽  
Adilson Candido da Silva
Keyword(s):  
Molecular Imprinted Polymer ◽  
Imprinted Polymer

Preparation of novel arsenic-imprinted polymer for the selective extraction and enhanced adsorption of toxic As3+ ions from the aqueous environment

2019 ◽  
Vol 77 (10) ◽  
pp. 5261-5279 ◽  
Author(s):  
Muhammad Saqaf Jagirani ◽  
Aamna Balouch ◽  
Sarfaraz Ahmed Mahesar ◽  
Ameet Kumar ◽  
Abdullah ◽  
...  
Keyword(s):  
Selective Extraction ◽  
Aqueous Environment ◽  
Imprinted Polymer ◽  
Enhanced Adsorption

Selective extraction of progesterone hormones from environmental and biological samples using a polypyrrole molecularly imprinted polymer and determination by gas chromatography

2016 ◽  
Vol 8 (8) ◽  
pp. 1813-1827 ◽  
Author(s):  
A. Nezhadali ◽  
Z. Es’haghi ◽  
A. Khatibi
Keyword(s):  
Gas Chromatography ◽  
Molecularly Imprinted Polymer ◽  
Biological Samples ◽  
Selective Extraction ◽  
Chemical Oxidation ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Batch Extraction ◽  
Environmental And Biological Samples

A Molecularly Imprinted Polymer (MIP) was chemically prepared for the selective batch extraction of progesterone (PGN) hormones by chemical oxidation of pyrrole using FeCl3.

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