Development of an on-line high performance liquid chromatography detection system for human cytochrome P450 1A2 inhibitors in extracts of natural products

2007 ◽  
Vol 1141 (1) ◽  
pp. 81-89 ◽  
Author(s):  
Suzanne M.F. Jeurissen ◽  
Frank W. Claassen ◽  
Jaroslav Havlik ◽  
Evelien E. Bouwmans ◽  
Nicole H.P. Cnubben ◽  
...  
Keyword(s):  
Natural Products ◽  
High Performance Liquid Chromatography ◽  
Cytochrome P450 ◽  
Liquid Chromatography ◽  
High Performance ◽  
Detection System ◽  
Cytochrome P450 1A2 ◽  
Human Cytochrome ◽  
On Line

scholarly journals An in vitro affinity-based method for studying herb–drug interactions for direct identification of cytochrome P450 1A2, 3A4, and 2C9 specific ligands from herbal extracts using ultrafiltration-high performance liquid chromatography

RSC Advances ◽  
2018 ◽  
Vol 8 (16) ◽  
pp. 8944-8949 ◽  
Author(s):  
Zhiqiang Wang ◽  
Seung Hwan Hwang ◽  
Guanglei Zuo ◽  
Set Byeol Kim ◽  
Soon Sung Lim
Keyword(s):  
High Performance Liquid Chromatography ◽  
Cytochrome P450 ◽  
Liquid Chromatography ◽  
Natural Product ◽  
High Performance ◽  
Target System ◽  
Herbal Extracts ◽  
Cytochrome P450 1A2 ◽  
Direct Identification

The specific ligands in natural product extracts could be identified from a multi-target system by ultrafiltration-high performance liquid chromatography using competitive probes.

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