Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites

CHEST Journal ◽  
2016 ◽  
Vol 150 (4) ◽  
pp. 574A ◽  
Author(s):  
Sandeep Chennadi ◽  
Prangthip Charoenpong ◽  
Sikander Zulqarnain
2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Vital Da Silva Domingues ◽  
Vital Da Silva Domingues ◽  
Isabel Neves ◽  
Susana Garrido ◽  
Inês Ferreira ◽  
...  

Medicine ◽  
2020 ◽  
Vol 99 (51) ◽  
pp. e23661
Author(s):  
Guo-Hua Zhang ◽  
Ling-Ling Zhang ◽  
Yu-Hua Wang ◽  
Wen-Bin Shen

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Dilek Ersil Soysal ◽  
Sezin Hizar Turan ◽  
Mustafa Ozmen ◽  
Mete Pekdiker ◽  
Mehmet Eren Kalender ◽  
...  

During the course of the disease a patient with systemic lupus erythematosus (SLE) may develop inflammation of one or more serous membranes, resulting in pleural, peritoneal, or pericardial effusion. Chylous ascites and chylothorax have rarely been described in patients with SLE. Therefore, in parallel with the analysis of blood samples, detailed analysis of the effusions should be carried out. Supportive measures are often needed to relieve the symptoms of chylothorax or chylous ascites together with the treatment of the primary disease. The available literature had reported just 4 cases of chylous ascites and/or chylothorax in association with SLE, and this patient presented here is one of the rare cases apart from the reported ones.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Guan-Liang Chen ◽  
Deng-Ho Yang ◽  
Wen-Hsiu Hsu

Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder with involvement of multiple organs. Various forms of serositis, including pleural effusion, pericardial effusion, and ascites, may be found during the course of SLE. Peritoneal involvement by ascites is common in the initial presentation of SLE. However, chylous ascites is uncommon in SLE patients. Here, we describe a 93-year-old female with initial presentation of chylous ascites during SLE flares. Marked distention and an ovoid shape of the abdomen were observed. Shifting dullness and central tympanic sounds were found on percussion. Rales were heard in bilateral breathing sounds, multiple oral ulcers appeared in the oral cavity, and chest images showed bilateral pleural effusion. Abdominal sonography revealed moderate ascites and pleural effusion. Neither organisms nor malignant cells were revealed in the culture or cytology of ascites and pleural effusion. The diagnosis of SLE was arrived at by positive antinuclear antibody (ANA), discoid rash, oral ulcers, serositis (pleural effusion and ascites), and proteinuria. The patient received intravenous methylprednisolone 250 mg/day for three days. The pleural effusion resolved dramatically after steroid therapy and abdominal distention related to ascites formation subsided obviously.


Author(s):  
Francis R. Comerford ◽  
Alan S. Cohen

Mice of the inbred NZB strain develop a spontaneous disease characterized by autoimmune hemolytic anemia, positive lupus erythematosus cell tests and antinuclear antibodies and nephritis. This disease is analogous to human systemic lupus erythematosus. In ultrastructural studies of the glomerular lesion in NZB mice, intraglomerular dense deposits in mesangial, subepithelial and subendothelial locations were described. In common with the findings in many examples of human and experimental nephritis, including many cases of human lupus nephritis, these deposits were amorphous or slightly granular in appearance with no definable substructure.We have recently observed structured deposits in the glomeruli of NZB mice. They were uncommon and were found in older animals with severe glomerular lesions by morphologic criteria. They were seen most commonly as extracellular elements in subendothelial and mesangial regions. The deposits ranged up to 3 microns in greatest dimension and were often adjacent to deposits of lipid-like round particles of 30 to 250 millimicrons in diameter and with amorphous dense deposits.


2000 ◽  
Vol 6 (7) ◽  
pp. 821-825 ◽  
Author(s):  
ELIZABETH LERITZ ◽  
JASON BRANDT ◽  
MELISSA MINOR ◽  
FRANCES REIS-JENSEN ◽  
MICHELLE PETRI

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