scholarly journals Are Epstein-Barr Virus-positive and -negative Gastric Carcinomas, With Lymphoid Stroma, Single Entity or Different Entities?

2015 ◽  
Vol 13 (10) ◽  
pp. 1745-1747 ◽  
Author(s):  
Wei Kang ◽  
Ka Fai To
Keyword(s):  
Epstein Barr Virus ◽  
Gastric Carcinomas ◽  
Barr Virus ◽  
Single Entity ◽  
Lymphoid Stroma ◽  
Epstein Barr

scholarly journals Very Low Risk of Lymph Node Metastasis in Epstein-Barr Virus-associated Early Gastric Carcinoma With Lymphoid Stroma

2020 ◽  
Author(s):  
Yuqing Cheng ◽  
Xiaoli Zhou ◽  
Kequn Xu ◽  
Jin Huang ◽  
Qin Huang
Keyword(s):  
Gastric Carcinoma ◽  
Epstein Barr Virus ◽  
Early Gastric Carcinoma ◽  
Invasion Depth ◽  
Gastric Carcinomas ◽  
Barr Virus ◽  
Node Metastasis ◽  
Lymphoid Stroma ◽  
Poor Differentiation ◽  
Epstein Barr

Abstract Epstein-Barr virus-associated early gastric carcinoma with lymphoid stroma (EBV-GCLS) is a rare variant of early gastric carcinomas. Clinicopathological features of this variant remain obscure, especially in Chinese patients. By a retrospective review of 595 consecutive radical gastrectomies for early gastric carcinoma from 2006 to 2018, we identified 8 (1.3%, 8/595) EBV-GCLS cases. Clinicopathologic characteristics were compared between EBV-GCLSs and 109 conventional early gastric carcinomas, which were divided into 3 subgroups, according to the invasion depth. All 8 EBV-GCLSs occurred in male patients and invaded deep submucosa (SM2) without lymph node metastasis (LNM), four (50%) of which had synchronous non-gastric malignant tumors (3 gastric gastrointestinal stromal tumors and 1 primary clear cell renal cell carcinoma), and four (50%) arose in the proximal stomach. Compared to conventional early gastric carcinomas, EBV-GCLS was more frequent with SM2 invasion, poor differentiation, and synchronous non-gastric carcinoma tumor, but not in age, gender, macroscopic type, location, size, perineural invasion, lymphovascular invasion, and pathologic stage. In invasion-depth stratified comparisons with the SM2 subgroup, the frequency of LNM in EBV-GCLS was significantly lower than that of conventional early gastric carcinomas ( p < 0.05) and the 5-year survival rate of patients with EBV-GCLS was better than that of conventional early gastric carcinomas in 3 subgroups (100% vs 91.5%, 85.7%, 83.9%, respectively), although the differences did not reach a statistically significant level due to the small sample size. In conclusion, Even with poor differentiation and SM2 invasion, EBV-GCLS showed very low risk of LNM and may be a candidate for endoscopic therapy.

Epstein-Barr virus in gastric carcinomas with lymphoid stroma

2000 ◽  
Vol 37 (4) ◽  
pp. 309-315 ◽  
Author(s):  
M S Chang ◽  
W H Kim ◽  
C W Kim ◽  
Y I Kim
Keyword(s):  
Epstein Barr Virus ◽  
Gastric Carcinomas ◽  
Barr Virus ◽  
Lymphoid Stroma ◽  
Epstein Barr

scholarly journals Carcinoma of stomach and breast with lymphoid stroma: localisation of Epstein-Barr virus.

1994 ◽  
Vol 47 (6) ◽  
pp. 538-540 ◽  
Author(s):  
K Horiuchi ◽  
K Mishima ◽  
M Ohsawa ◽  
K Aozasa
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
Lymphoid Stroma ◽  
Epstein Barr

Epstein-Barr Virus in Gastric Carcinomas from Singapore

1996 ◽  
Vol 4 (3) ◽  
pp. 149-158
Author(s):  
Gary D. Clark ◽  
Yoke Sun Lee ◽  
Kyung-Whan Min ◽  
S. Terence Dunn
Keyword(s):  
Epstein Barr Virus ◽  
Gastric Carcinomas ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals A case of Epstein-Barr virus-associated carcinoma with lymphoid stroma

2020 ◽  
Vol 96 (1) ◽  
pp. 93-94
Author(s):  
Akie Sakakura ◽  
Hiroyuki Ariga ◽  
Yuri Kumakura ◽  
Junya Kashimura
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
Lymphoid Stroma ◽  
Epstein Barr

Undifferentiated Carcinoma with Lymphoid Stroma of the Major Salivary Glands

1990 ◽  
Vol 99 (3) ◽  
pp. 236-238 ◽  
Author(s):  
Karen R. Cleary ◽  
John G. Batsakis
Keyword(s):  
Salivary Glands ◽  
Epstein Barr Virus ◽  
Undifferentiated Carcinoma ◽  
Response To Therapy ◽  
Lymphoepithelial Carcinoma ◽  
Lymphoepithelial Lesion ◽  
Barr Virus ◽  
Lymphoid Stroma ◽  
Major Salivary Glands ◽  
Epstein Barr

Undifferentiated carcinoma with lymphoid stroma or lymphoepithelial carcinoma of the major salivary glands is a demographically and histopathologically unique malignancy. Although whites may have the disease, it is preponderantly a carcinoma of North American Eskimos and native Greenlanders. The carcinoma shares many features with undifferentiated nasopharyngeal carcinomas, from which it must be distinguished: histologic appearance, putative relationship with Epstein-Barr virus, predilection for mongoloid races, and response to therapy. In some cases, the carcinoma appears to have evolved from a lymphoepithelial lesion.

scholarly journals Epstein-Barr Virus, Beta-Catenin, and E-cadherin in Gastric Carcinomas

2007 ◽  
Vol 22 (5) ◽  
pp. 855 ◽  
Author(s):  
In Mok Jung ◽  
Jung Kee Chung ◽  
Young A Kim ◽  
Je Eun Kim ◽  
Seung Chul Heo ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Beta Catenin ◽  
Gastric Carcinomas ◽  
Barr Virus ◽  
Epstein Barr ◽  
E Cadherin
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