Virologic Response to Therapy Increases Health-Related Quality of Life for Patients With Chronic Hepatitis B

2012 ◽  
Vol 10 (3) ◽  
pp. 291-296 ◽  
Author(s):  
Jeong Han Kim ◽  
So Young Kwon ◽  
Young Sok Lee ◽  
Joon Hyoek Lee ◽  
Yil–Seob Lee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Virologic Response ◽  
Response To Therapy ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Health-related quality of life in patients with chronic hepatitis B

2007 ◽  
Vol 27 (8) ◽  
pp. 1119-1125 ◽  
Author(s):  
Silvia Bondini ◽  
Jillian Kallman ◽  
Amy Dan ◽  
Zahra Younoszai ◽  
Lolita Ramsey ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Assessing health-related quality of life and health utilities in patients with chronic hepatitis B-related diseases in China: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e047475
Author(s):  
Meng Zhang ◽  
Yaoguang Li ◽  
Zihao Fan ◽  
Dongqi Shen ◽  
Xueying Huang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related ◽  
Utility Scores

ObjectivesThe health-related quality of life (HRQoL) and utilities of patients with chronic hepatitis B (CHB) virus infection, including compensated cirrhosis (CC), decompensated cirrhosis (DC) and different stages of hepatocellular carcinoma (HCC), have not been well described in China. This study aimed to evaluate HRQoL and utilities and provide parameters for the economic evaluation of CHB-related diseases.MethodsWe conducted a multicentre cross-sectional and study to measure the HRQoL of patients with CHB, CC, DC and HCC using the Chinese short form (SF) 36 health survey V.2. The utilities were extracted based on the SF-six dimension scoring model. Multivariable regression analyses identified the effects on HRQoL.ResultsA total of 1071 patients (639 with CHB, 125 with CC, 85 with DC and 222 with HCC) were invited to complete the questionnaire. Physical HRQoL was not impaired in the CHB stage, while mental HRQoL was significantly impaired. Physical composite summary scores have a more significant decrease than mental composite summary scores at the advanced stages (CC, DC and HCC). The utility scores of CHB only, CC, DC and HCC were 0.773, 0.750, 0.683 and 0.640, respectively. The utility scores in the early, middle and terminal stages of HCC were 0.656, 0.635 and 0.615, respectively.ConclusionSlowing the progress of CHB-related diseases and providing psychological support early are the key points to improving the quality of life with the diseases. The utility values estimated in this study can provide a vital instrument for cost-effectiveness studies on CHB-related diseases.

scholarly journals Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B

2019 ◽  
Vol 16 (2) ◽  
pp. 255 ◽  
Author(s):  
Thuc Vu ◽  
Thieu Le ◽  
Anh Dang ◽  
Long Nguyen ◽  
Binh Nguyen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Depressive Symptoms ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Multivariate Logistic Regression Model ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Depression is considered one of the most prevalent psychiatric disorders among patients with hepatitis B virus (HBV)-related liver disease and has adverse effects on the disease progression. However, there is a scarcity of studies contributing to the assessement of depression in hepatitis B patients. There is also little research into risk factors, particularly underlying socio-economic factors in Vietnam where the prevalence of hepatitis B is high. This study aimed to examine depression and identify whether differences in socio-economic status is related to the level of depression amongst chronic hepatitis B patients. A cross-sectional study was conducted on 298 patients with chronic hepatitis B at The Chronic Hepatitis Clinic in the Viet-Tiep Hospital, Hai Phong, Vietnam. The Patient Health Questionnaire-9 (PHQ-9) and EuroQol-5 dimensions-5 levels (EQ-5D-5L) were used to assess the severity of depression and health-related quality of life (HRQOL). Of chronic hepatitis B patients, 37.5% experienced depressive symptoms and most of them suffered minimal depressive symptoms (31.4%). According to the result of the multivariate logistic regression model, we found that higher age, lower income level, unemployement, living with spouse/partners were positively associated with having depression. Furthermore, having physical health problems and lower health-related quality of life were also related to a higher risk of depression. We recommend family support, financial support and active participation in consultation should be conducted during treatment to improve the quality of life and the emotional state of HBV patients.

Health-related quality of life in chronic hepatitis B patients

Hepatology ◽  
2008 ◽  
Vol 47 (4) ◽  
pp. 1108-1117 ◽  
Author(s):  
Siew Chin Ong ◽  
Belinda Mak ◽  
Myat Oo Aung ◽  
Shu-Chuen Li ◽  
Seng-Gee Lim
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Health-Related Quality of Life among a Sample of Chronic Hepatitis B Patients in AL-Najaf Province /Iraq.

2020 ◽  
Vol 29 (1) ◽  
pp. 33-40
Author(s):  
Hanan N. Najaf ◽  
Dheyaa J. Kadhim
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Short Form ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Male Patients

Abstract The effect of physical and mental health on the feelings of personal welfare are known as health-related quality of life. Infection with hepatitis B virus is a major global health problem. Health-related quality of life was emerged as an important consideration in the care of patients with chronic hepatitis B infection. The aim of the current study was to measure health-related quality of life among a sample of chronic hepatitis B patients in AL-Najaf city/Iraq. The current study was cross-sectional study carried out on (104) already diagnosed chronic viral hepatitis B patients who attended the Gastroenterology and Hepatology Center/Al-Sader Medical City/Najaf during November 2018 to May 2019. In addition, 100 apparently healthy subjects were included as a control group. Health related quality of life was measured using the Arabic version of the Short Form 36. The health-related quality of life of patients with chronic hepatitis B infection was affected by the disease in a highly significant manner where the median scores for all health-related quality of life domains were significantly lower in patients than in controls. Physical functioning score was negatively correlated to age, significantly higher in male patients, significantly higher in high educated patients, significantly higher in single patients, and significantly higher in patients with no children. Role limitation due to physical health score was negatively correlated to age, significantly higher in those with no children. Energy/fatigue score was negatively correlated to age, and significantly higher in male patients. Social functioning score was significantly higher in male patients. Pain score was negatively correlated with age. Physical functioning score was negatively correlated to serum albumin. Social functioning and general health score were negatively correlated to viral load. In conclusion, chronic hepatitis B patients showed significantly lower health-related quality of life scores in various domains compared to healthy control subjects in AL-Najaf province /Iraq.  Key words: Health-Related Quality of Life, Hepatitis B,  Short Form 36, AL-Najaf, Iraq

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