Comparing ion diffusion in alternative cementitious materials in real time by using non-destructive X-ray imaging

2017 ◽  
Vol 82 ◽  
pp. 67-79 ◽  
Author(s):  
Mehdi Khanzadeh Moradllo ◽  
M. Tyler Ley
Keyword(s):  
Real Time ◽  
Cementitious Materials ◽  
Ion Diffusion ◽  
X Ray ◽  
X Ray Imaging ◽  
Non Destructive

Using X-ray imaging to investigate in-situ ion diffusion in cementitious materials

2017 ◽  
Vol 136 ◽  
pp. 88-98 ◽  
Author(s):  
Mehdi Khanzadeh Moradllo ◽  
Qinang Hu ◽  
M. Tyler Ley
Keyword(s):  
Cementitious Materials ◽  
Ion Diffusion ◽  
X Ray ◽  
X Ray Imaging

A Magnetically Guided Self‐Rolled Microrobot for Targeted Drug Delivery, Real‐Time X‐Ray Imaging, and Microrobot Retrieval

2021 ◽  
pp. 2001681
Author(s):  
Kim Tien Nguyen ◽  
Gwangjun Go ◽  
Zhen Jin ◽  
Bobby Aditya Darmawan ◽  
Ami Yoo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Real Time ◽  
Targeted Drug Delivery ◽  
X Ray ◽  
X Ray Imaging ◽  
Targeted Drug

scholarly journals Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson’s Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography

2020 ◽  
Vol 14 ◽  
Author(s):  
Hung Tri Tran ◽  
Esther H. R. Tsai ◽  
Amanda J. Lewis ◽  
Tim Moors ◽  
J. G. J. M. Bol ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Human Brain ◽  
Brain Tissue ◽  
Multispectral Imaging ◽  
Alpha Synuclein ◽  
Label Free ◽  
Myelinated Axons ◽  
X Ray ◽  
X Ray Imaging ◽  
Non Destructive

Gaining insight to pathologically relevant processes in continuous volumes of unstained brain tissue is important for a better understanding of neurological diseases. Many pathological processes in neurodegenerative disorders affect myelinated axons, which are a critical part of the neuronal circuitry. Cryo ptychographic X-ray computed tomography in the multi-keV energy range is an emerging technology providing phase contrast at high sensitivity, allowing label-free and non-destructive three dimensional imaging of large continuous volumes of tissue, currently spanning up to 400,000 μm3. This aspect makes the technique especially attractive for imaging complex biological material, especially neuronal tissues, in combination with downstream optical or electron microscopy techniques. A further advantage is that dehydration, additional contrast staining, and destructive sectioning/milling are not required for imaging. We have developed a pipeline for cryo ptychographic X-ray tomography of relatively large, hydrated and unstained biological tissue volumes beyond what is typical for the X-ray imaging, using human brain tissue and combining the technique with complementary methods. We present four imaged volumes of a Parkinson’s diseased human brain and five volumes from a non-diseased control human brain using cryo ptychographic X-ray tomography. In both cases, we distinguish neuromelanin-containing neurons, lipid and melanic pigment, blood vessels and red blood cells, and nuclei of other brain cells. In the diseased sample, we observed several swellings containing dense granular material resembling clustered vesicles between the myelin sheaths arising from the cytoplasm of the parent oligodendrocyte, rather than the axoplasm. We further investigated the pathological relevance of such swollen axons in adjacent tissue sections by immunofluorescence microscopy for phosphorylated alpha-synuclein combined with multispectral imaging. Since cryo ptychographic X-ray tomography is non-destructive, the large dataset volumes were used to guide further investigation of such swollen axons by correlative electron microscopy and immunogold labeling post X-ray imaging, a possibility demonstrated for the first time. Interestingly, we find that protein antigenicity and ultrastructure of the tissue are preserved after the X-ray measurement. As many pathological processes in neurodegeneration affect myelinated axons, our work sets an unprecedented foundation for studies addressing axonal integrity and disease-related changes in unstained brain tissues.

scholarly journals Exploiting coherence for real-time studies by single-bunch imaging

2014 ◽  
Vol 21 (4) ◽  
pp. 815-818 ◽  
Author(s):  
A. Rack ◽  
M. Scheel ◽  
L. Hardy ◽  
C. Curfs ◽  
A. Bonnin ◽  
...  
Keyword(s):  
Real Time ◽  
European Synchrotron Radiation Facility ◽  
Photon Flux ◽  
Photon Flux Density ◽  
Bunch Length ◽  
X Ray ◽  
Aqueous Foam ◽  
Insertion Device ◽  
X Ray Imaging ◽  
Absorption Contrast

First real-time studies of ultra-fast processes by single-bunch imaging at the European Synchrotron Radiation Facility are reported. By operating the storage ring of the ESRF in single-bunch mode with its correspondingly increased electron bunch charge density per singlet, the polychromatic photon flux density at insertion-device beamlines is sufficient to capture hard X-ray images exploiting the light from a single bunch (the corresponding bunch length is 140 ps FWHM). Hard X-ray imaging with absorption contrast as well as phase contrast in combination with large propagation distances is demonstrated using spatial samplings of 11 µm and 35 µm pixel size. The images acquired allow one to track crack propagation in a bursting piece of glass, breaking of an electrical fuse as well as cell wall rupture in an aqueous foam. Future developments and their potential in the frame of the proposed Phase II of the ESRF Upgrade Program are discussed.

Rapid, Non-destructive Inspection and Classification of Inhalation Blisters Using Low-Energy X-ray Imaging

2018 ◽  
Vol 13 (3) ◽  
pp. 270-282 ◽  
Author(s):  
Nagaraja Rao ◽  
Brian Ament ◽  
Richard Parmee ◽  
Jonathan Cameron ◽  
Martin Mayo
Keyword(s):  
Low Energy ◽  
X Ray ◽  
X Ray Imaging ◽  
Non Destructive

Development of Real Time High Energy X-Ray Imaging System for Use in Dynamic Fluoroscopy of Aero Gas Turbines

1975 ◽  
Author(s):  
A. E. Stewart
Keyword(s):  
Real Time ◽  
Gas Turbines ◽  
Imaging System ◽  
High Energy ◽  
Cesium Iodide ◽  
Imaging Systems ◽  
X Ray ◽  
X Ray Imaging ◽  
Different Types

This paper discusses the development of a real-time high energy x-ray imaging system for use in dynamic fluoroscopy of aero gas turbines. In order to cover the range of subjects on gas turbines, over ten combinations of film and screen types are used. Three different types of x-ray imaging systems were considered for use: direct type intensifiers (cesium iodide phosphors), and indirect type intensifiers — Marconi “Marionette” and the Oude Delft “Delcalix.”

Sign in / Sign up

Export Citation Format

Share Document