scholarly journals Compensatory Cell Movements Confer Robustness to Mechanical Deformation during Embryonic Development

Cell Systems ◽  
2016 ◽  
Vol 3 (2) ◽  
pp. 160-171 ◽  
Author(s):  
Rob Jelier ◽  
Angela Kruger ◽  
Jim Swoger ◽  
Timo Zimmermann ◽  
Ben Lehner
Keyword(s):  
Embryonic Development ◽  
Mechanical Deformation ◽  
Cell Movements

Live Confocal Analysis of Fertilization and Early Development

2001 ◽  
Vol 7 (S2) ◽  
pp. 1012-1013
Author(s):  
Uyen Tram ◽  
William Sullivan
Keyword(s):  
Drosophila Melanogaster ◽  
Embryonic Development ◽  
Real Time ◽  
Early Development ◽  
Fluorescent Probes ◽  
Primary Defect ◽  
Fluorescent Analysis ◽  
Dynamic Event ◽  
Enormous Amount ◽  
Fluorescent Studies

Embryonic development is a dynamic event and is best studied in live animals in real time. Much of our knowledge of the early events of embryogenesis, however, comes from immunofluourescent analysis of fixed embryos. While these studies provide an enormous amount of information about the organization of different structures during development, they can give only a static glimpse of a very dynamic event. More recently real-time fluorescent studies of living embryos have become much more routine and have given new insights to how different structures and organelles (chromosomes, centrosomes, cytoskeleton, etc.) are coordinately regulated. This is in large part due to the development of commercially available fluorescent probes, GFP technology, and newly developed sensitive fluorescent microscopes. For example, live confocal fluorescent analysis proved essential in determining the primary defect in mutations that disrupt early nuclear divisions in Drosophila melanogaster. For organisms in which GPF transgenics is not available, fluorescent probes that label DNA, microtubules, and actin are available for microinjection.

ADHD therapy with methylphenidate in mothers – a danger for embryonic development?

2014 ◽  
Vol 47 (06) ◽  
Author(s):  
N Bergemann ◽  
K Boyle ◽  
WE Paulus
Keyword(s):  
Embryonic Development
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