scholarly journals Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate

Cell Reports ◽  
2019 ◽  
Vol 29 (3) ◽  
pp. 603-616.e5
Author(s):  
Hiroyuki N. Arai ◽  
Fuminori Sato ◽  
Takuya Yamamoto ◽  
Knut Woltjen ◽  
Hiroshi Kiyonari ◽  
...  
Keyword(s):  
Neural Crest ◽  
Cell Fate ◽  
Neural Crest Cell ◽  
Bmp Signaling ◽  
Cardiac Neural Crest ◽  
Crest Cell

scholarly journals Role of endothelin-A receptor in cardiac neural crest cell fate

2011 ◽  
Vol 356 (1) ◽  
pp. 197-198
Author(s):  
Yanping Zhang ◽  
Mitchell T. McKnight ◽  
L. Bruno Ruest
Keyword(s):  
Neural Crest ◽  
Cell Fate ◽  
Neural Crest Cell ◽  
Cardiac Neural Crest ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Crest Cell

A role for rhoB in the delamination of neural crest cells from the dorsal neural tube

Development ◽  
1998 ◽  
Vol 125 (24) ◽  
pp. 5055-5067 ◽  
Author(s):  
J.P. Liu ◽  
T.M. Jessell
Keyword(s):  
Neural Crest ◽  
Cell Fate ◽  
Neural Tube ◽  
Neural Crest Cell ◽  
Neural Crest Cells ◽  
Bmp Signaling ◽  
Dorsal Neural Tube ◽  
Rho Family ◽  
Neural Crest Differentiation ◽  
Crest Cell

The differentiation of neural crest cells from progenitors located in the dorsal neural tube appears to involve three sequential steps: the specification of premigratory neural crest cell fate, the delamination of these cells from the neural epithelium and the migration of neural crest cells in the periphery. BMP signaling has been implicated in the specification of neural crest cell fate but the mechanisms that control the emergence of neural crest cells from the neural tube remain poorly understood. To identify molecules that might function at early steps of neural crest differentiation, we performed a PCR-based screen for genes induced by BMPs in chick neural plate cells. We describe the cloning and characterization of one gene obtained from this screen, rhoB, a member of the rho family GTP-binding proteins. rhoB is expressed in the dorsal neural tube and its expression persists transiently in migrating neural crest cells. BMPs induce the neural expression of rhoB but not the more widely expressed rho family member, rhoA. Inhibition of rho activity by C3 exotoxin prevents the delamination of neural crest cells from neural tube explants but has little effect on the initial specification of premigratory neural crest cell fate or on the later migration of neural crest cells. These results suggest that rhoB has a role in the delamination of neural crest cells from the dorsal neural tube.

scholarly journals Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion

2018 ◽  
Vol 247 (12) ◽  
pp. 1286-1296 ◽  
Author(s):  
Kimberly E. Inman ◽  
Carlo Donato Caiaffa ◽  
Kristin R. Melton ◽  
Lisa L. Sandell ◽  
Annita Achilleos ◽  
...  
Keyword(s):  
Cell Migration ◽  
Neural Crest ◽  
Neural Crest Cell ◽  
Outflow Tract ◽  
Cardiac Neural Crest ◽  
Neural Crest Cell Migration ◽  
Crest Cell

scholarly journals The Hippo pathway member YAP enhances human neural crest cell fate and migration

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Christopher J. Hindley ◽  
Alexandra Larisa Condurat ◽  
Vishal Menon ◽  
Ria Thomas ◽  
Luis M. Azmitia ◽  
...  
Keyword(s):  
Neural Crest ◽  
Cell Fate ◽  
Hippo Pathway ◽  
Neural Crest Cell ◽  
And Migration ◽  
The Hippo Pathway ◽  
Crest Cell

scholarly journals BMP signaling is necessary for neural crest cell migration and ganglion formation in the enteric nervous system

2005 ◽  
Vol 122 (6) ◽  
pp. 821-833 ◽  
Author(s):  
Allan M. Goldstein ◽  
Katherine C. Brewer ◽  
Adele M. Doyle ◽  
Nandor Nagy ◽  
Drucilla J. Roberts
Keyword(s):  
Nervous System ◽  
Cell Migration ◽  
Neural Crest ◽  
Enteric Nervous System ◽  
Neural Crest Cell ◽  
Bmp Signaling ◽  
Neural Crest Cell Migration ◽  
Crest Cell

Regulation of cranial neural crest cell fate by Irf6 and Twist1 interaction

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Walid D. Fakhouri ◽  
Jessica Wildgrube Bertol ◽  
Victoria K. Xie ◽  
Shelby Johnston ◽  
Kelsea Hubka ◽  
...  
Keyword(s):  
Neural Crest ◽  
Cell Fate ◽  
Neural Crest Cell ◽  
Cranial Neural Crest ◽  
Cranial Neural Crest Cell ◽  
Crest Cell

scholarly journals A MMP‐independent role for TIMP‐2 during cardiac neural crest cell migration

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Philip R Brauer ◽  
William G Stetler‐Stevenson ◽  
Lan Uyen Tran ◽  
Mark V Reedy
Keyword(s):  
Cell Migration ◽  
Neural Crest ◽  
Neural Crest Cell ◽  
Cardiac Neural Crest ◽  
Neural Crest Cell Migration ◽  
Crest Cell
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