scholarly journals Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate

Cell Reports ◽  
2019 ◽  
Vol 28 (6) ◽  
pp. 1499-1510.e6 ◽  
Author(s):  
Preston D. Crowell ◽  
Jonathan J. Fox ◽  
Takao Hashimoto ◽  
Johnny A. Diaz ◽  
Héctor I. Navarro ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Human Prostate ◽  
Luminal Progenitor ◽  
Aging Mouse ◽  
Luminal Progenitor Cells

scholarly journals Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

Cell ◽  
2014 ◽  
Vol 159 (1) ◽  
pp. 163-175 ◽  
Author(s):  
Wouter R. Karthaus ◽  
Phillip J. Iaquinta ◽  
Jarno Drost ◽  
Ana Gracanin ◽  
Ruben van Boxtel ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Human Prostate ◽  
Luminal Progenitor ◽  
Luminal Progenitor Cells ◽  
Organoid Cultures

scholarly journals A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice

Oncogene ◽  
2013 ◽  
Vol 33 (4) ◽  
pp. 411-420 ◽  
Author(s):  
J L Little ◽  
V Serzhanova ◽  
E Izumchenko ◽  
B L Egleston ◽  
E Parise ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Mammary Tumorigenesis ◽  
Luminal Progenitor ◽  
Luminal Progenitor Cells

scholarly journals Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

2009 ◽  
Vol 23 (20) ◽  
pp. 2382-2387 ◽  
Author(s):  
D. Yamaji ◽  
R. Na ◽  
Y. Feuermann ◽  
S. Pechhold ◽  
W. Chen ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Progenitor Cells ◽  
Luminal Progenitor ◽  
Luminal Progenitor Cells

scholarly journals Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

Cell Reports ◽  
2015 ◽  
Vol 13 (10) ◽  
pp. 2147-2158 ◽  
Author(s):  
Supreet Agarwal ◽  
Paul G. Hynes ◽  
Heather S. Tillman ◽  
Ross Lake ◽  
Wassim G. Abou-Kheir ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Luminal Progenitor ◽  
Prostate Tumors ◽  
Luminal Progenitor Cells

scholarly journals Inference of tissue relative proportions of the breast epithelial cell types luminal progenitor, basal, and luminal mature

2021 ◽  
Author(s):  
Thomas E Bartlett ◽  
Swati Chandna ◽  
Sandipan Roy
Keyword(s):  
Progenitor Cells ◽  
Hormone Receptor ◽  
Breast Tissue ◽  
Breast Tumour ◽  
Breast Epithelial Cell ◽  
Fanconi Anaemia ◽  
Breast Cancers ◽  
Luminal Progenitor ◽  
Tissue Samples ◽  
Luminal Progenitor Cells

Hormone receptor negative breast cancers are highly aggressive, and are thought to originate from a subtype of epithelial cells called the luminal progenitor. In this paper, we show how to quantify the number of luminal progenitor cells as well as other epithelial subtypes in breast tissue samples using DNA and RNA based measurements. We find elevated levels of these hormone receptor negative luminal progenitor cells in breast tumour biopsies of hormone receptor negative cancers, as well as in healthy breast tissue samples from BRCA1 (FANCS) mutation carriers. We also find that breast tumours from carriers of heterozygous mutations in non-BRCA Fanconi Anaemia pathway genes are much more likely to be hormone receptor negative.

scholarly journals Spatially correlated phenotyping reveals K5-positive luminal progenitor cells and p63-K5/14-positive stem cell-like cells in human breast epithelium

2018 ◽  
Vol 98 (8) ◽  
pp. 1065-1075 ◽  
Author(s):  
Werner Boecker ◽  
Laura van Horn ◽  
Göran Stenman ◽  
Christine Stürken ◽  
Udo Schumacher ◽  
...  
Keyword(s):  
Stem Cell ◽  
Progenitor Cells ◽  
Luminal Progenitor ◽  
Human Breast ◽  
Breast Epithelium ◽  
Spatially Correlated ◽  
Luminal Progenitor Cells

scholarly journals Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14

2011 ◽  
Vol 31 (22) ◽  
pp. 4609-4622 ◽  
Author(s):  
M.-L. Asselin-Labat ◽  
K. D. Sutherland ◽  
F. Vaillant ◽  
D. E. Gyorki ◽  
D. Wu ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Progenitor Cells ◽  
Luminal Progenitor ◽  
Putative Tumor Suppressor ◽  
Luminal Progenitor Cells
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