scholarly journals Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies

Cell Reports ◽  
2019 ◽  
Vol 28 (1) ◽  
pp. 65-77.e6 ◽  
Author(s):  
Éva M. Szegő ◽  
Antonio Dominguez-Meijide ◽  
Ellen Gerhardt ◽  
Annekatrin König ◽  
David J. Koss ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Mitochondrial Heat Shock Protein ◽  
Pathological Event

A mitochondrial heat shock protein from Crithidia fasciculata

1993 ◽  
Vol 59 (2) ◽  
pp. 191-200 ◽  
Author(s):  
Philip N. Effron ◽  
Al F. Torri ◽  
David M. Engman ◽  
John E. Donelson ◽  
Paul T. Englund
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Crithidia Fasciculata ◽  
Mitochondrial Heat Shock Protein

Characterization and expression analysis of a mitochondrial heat-shock protein 70 gene from the Antarctic moss Pohlia nutans

Polar Biology ◽  
2014 ◽  
Vol 37 (8) ◽  
pp. 1145-1155 ◽  
Author(s):  
Shenghao Liu ◽  
Jing Wang ◽  
Bailin Cong ◽  
Xiaohang Huang ◽  
Kaoshan Chen ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Expression Analysis ◽  
Heat Shock Protein 70 ◽  
Mitochondrial Heat Shock Protein ◽  
The Antarctic ◽  
Pohlia Nutans ◽  
Antarctic Moss

scholarly journals Mitochondrial Heat Shock Protein (Hsp) 70 and Hsp10 Cooperate in the Formation of Hsp60 Complexes

2015 ◽  
Vol 290 (18) ◽  
pp. 11611-11622 ◽  
Author(s):  
Lena Böttinger ◽  
Silke Oeljeklaus ◽  
Bernard Guiard ◽  
Sabine Rospert ◽  
Bettina Warscheid ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Hsp 70 ◽  
Mitochondrial Heat Shock Protein

scholarly journals The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential

2004 ◽  
Vol 279 (24) ◽  
pp. 25689-25695 ◽  
Author(s):  
Francesca Orsini ◽  
Enrica Migliaccio ◽  
Maurizio Moroni ◽  
Cristina Contursi ◽  
Veronica A. Raker ◽  
...  
Keyword(s):  
Membrane Potential ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Life Span ◽  
Heat Shock Protein 70 ◽  
Mitochondrial Heat Shock Protein

scholarly journals Characterization of Mitochondrial Heat Shock Protein 75 (mtHSP75) of the Big-belly Seahorse Hippocampus abdominalis

2015 ◽  
Vol 48 (3) ◽  
pp. 354-361
Author(s):  
Jiyeon Ko ◽  
Wan Qiang ◽  
Sukkyoung Lee ◽  
S.D.N.K. Bathige ◽  
Minyoung Oh ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Hippocampus Abdominalis ◽  
Mitochondrial Heat Shock Protein

scholarly journals HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases.

1993 ◽  
Vol 13 (10) ◽  
pp. 6304-6313 ◽  
Author(s):  
S A Leonhardt ◽  
K Fearson ◽  
P N Danese ◽  
T L Mason
Keyword(s):  
Thermal Stress ◽  
Heat Shock ◽  
Carbon Source ◽  
Heat Shock Protein ◽  
Elevated Temperatures ◽  
Regulatory Element ◽  
Nuclear Gene ◽  
Sequence Comparisons ◽  
Atpase Subunit ◽  
Mitochondrial Heat Shock Protein

The Saccharomyces cerevisiae nuclear gene for a 78-kDa mitochondrial heat shock protein (hsp78) was identified in a lambda gt11 expression library through immunological screening with an hsp78-specific monoclonal antibody. Sequencing of HSP78 revealed a long open reading frame capable of encoding an 811-amino-acid, 91.3-kDa basic protein with a putative mitochondrial leader sequence and two potential nucleotide-binding sites. Sequence comparisons revealed that hsp78 is a member of the highly conserved family of Clp proteins and is most closely related to the Escherichia coli ClpB protein, which is thought to be an ATPase subunit of an intracellular ATP-dependent protease. The steady-state levels of HSP78 transcripts and protein varied in response to both thermal stress and carbon source with an approximately 30-fold difference between repressed levels in cells growing fermentatively on glucose at 30 degrees C and derepressed levels in heat-shocked cells growing on a nonfermentable carbon source. The response to heat shock is consistent with the presence of a characteristic heat shock regulatory element in the 5'-flanking DNA. Submitochondrial fractionation showed that hsp78 is a soluble protein located in the mitochondrial matrix. Cells carrying disrupted copies of HSP78 lacked hsp78 but were not impaired in respiratory growth at normal and elevated temperatures or in the ability to survive and retain mitochondrial function after thermal stress. The absence of a strong mitochondrial phenotype in hsp78 mutants is comparable to the nonlethal phenotypes of mutations in other Clp genes in bacteria and yeast. HSP78 is the third gene, with SSC1 and HSP60, known to encode a yeast mitochondrial heat shock protein and the second gene, with HSP104, for a yeast ClpB homolog.

scholarly journals Mitochondrial Heat Shock Protein 60s Interact with What’s This Factor 9 to Regulate RNA Splicing ofccmFCandrpl2

2018 ◽  
Vol 60 (1) ◽  
pp. 116-125 ◽  
Author(s):  
Ya-Wen Hsu ◽  
Chien-Ta Juan ◽  
Chung-Min Wang ◽  
Guang-Yuh Jauh
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Rna Splicing ◽  
Mitochondrial Heat Shock Protein
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