scholarly journals MadID, a Versatile Approach to Map Protein-DNA Interactions, Highlights Telomere-Nuclear Envelope Contact Sites in Human Cells

Cell Reports ◽  
2018 ◽  
Vol 25 (10) ◽  
pp. 2891-2903.e5 ◽  
Author(s):  
Michal Sobecki ◽  
Charbel Souaid ◽  
Jocelyne Boulay ◽  
Vincent Guerineau ◽  
Daan Noordermeer ◽  
...  
Keyword(s):  
Nuclear Envelope ◽  
Human Cells ◽  
Dna Interactions ◽  
Contact Sites ◽  
Protein Dna Interactions

scholarly journals Direct membrane protein–DNA interactions required early in nuclear envelope assembly

2006 ◽  
Vol 173 (4) ◽  
pp. 469-476 ◽  
Author(s):  
Sebastian Ulbert ◽  
Melpomeni Platani ◽  
Stephanie Boue ◽  
Iain W. Mattaj
Keyword(s):  
Membrane Proteins ◽  
Membrane Protein ◽  
Nuclear Envelope ◽  
Dna Interactions ◽  
Membrane Recruitment ◽  
Free Dna ◽  
Protein Dna Interactions ◽  
Nuclear Envelope Assembly ◽  
Initial Membrane ◽  
Chromatin Proteins

Among the earliest events in postmitotic nuclear envelope (NE) assembly are the interactions between chromatin and the membranes that will fuse to form the NE. It has been proposed that interactions between integral NE proteins and chromatin proteins mediate initial membrane recruitment to chromatin. We show that several transmembrane NE proteins bind to DNA directly and that NE membrane proteins as a class are enriched in long, basic domains that potentially bind DNA. Membrane fractions that are essential for NE formation are shown to bind directly to protein-free DNA, and our data suggest that these interactions are critical for early steps in NE assembly.

Genome-wide mapping of allele-specific protein-DNA interactions in human cells

2008 ◽  
Vol 5 (4) ◽  
pp. 307-309 ◽  
Author(s):  
Nathaniel D Maynard ◽  
Jing Chen ◽  
Rhona K Stuart ◽  
Jian-Bing Fan ◽  
Bing Ren
Keyword(s):  
Specific Protein ◽  
Human Cells ◽  
Dna Interactions ◽  
Genome Wide ◽  
Protein Dna Interactions ◽  
Allele Specific
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