scholarly journals Theta Phase-Coordinated Memory Reactivation Reoccurs in a Slow-Oscillatory Rhythm during NREM Sleep

Cell Reports ◽  
2018 ◽  
Vol 25 (2) ◽  
pp. 296-301 ◽  
Author(s):  
Thomas Schreiner ◽  
Christian F. Doeller ◽  
Ole Jensen ◽  
Björn Rasch ◽  
Tobias Staudigl
Keyword(s):  
Nrem Sleep ◽  
Memory Reactivation ◽  
Theta Phase ◽  
Oscillatory Rhythm

scholarly journals Theta phase coordinated memory reactivation reoccurs in a slow-oscillatory rhythm during NREM sleep

2017 ◽  
Author(s):  
Thomas Schreiner ◽  
Christian F. Doeller ◽  
Ole Jensen ◽  
Björn Rasch ◽  
Tobias Staudigl
Keyword(s):  
Physiological State ◽  
Nrem Sleep ◽  
Neural Mechanisms ◽  
Theta Oscillations ◽  
Oscillatory Activity ◽  
Memory Reactivation ◽  
Specific Memory ◽  
Theta Phase ◽  
With Memory ◽  
Oscillatory Rhythm

It has been proposed that sleep’s contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated whether content-specific memory signatures associated with memory reactivation during wakefulness reoccur during subsequent sleep. We show that theta oscillations orchestrate the reactivation of memories, irrespective of the physiological state. Reactivation patterns during sleep autonomously re-emerged at a rate of 1 Hz, indicating a coordination by slow oscillatory activity.

scholarly journals Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Thomas Schreiner ◽  
Marit Petzka ◽  
Tobias Staudigl ◽  
Bernhard P. Staresina
Keyword(s):  
Memory Function ◽  
Nrem Sleep ◽  
Stimulus Category ◽  
Learning Material ◽  
Memory Reactivation ◽  
Eeg Recordings ◽  
Surface Eeg ◽  
Function Of Sleep ◽  
Prior Experiences

AbstractSleep is thought to support memory consolidation via reactivation of prior experiences, with particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) gating the information flow between relevant brain areas. However, empirical evidence for a role of endogenous memory reactivation (i.e., without experimentally delivered memory cues) for consolidation in humans is lacking. Here, we devised a paradigm in which participants acquired associative memories before taking a nap. Multivariate decoding was then used to capture endogenous memory reactivation during non-rapid eye movement (NREM) sleep in surface EEG recordings. Our results reveal reactivation of learning material during SO-spindle complexes, with the precision of SO-spindle coupling predicting reactivation strength. Critically, reactivation strength (i.e. classifier evidence in favor of the previously studied stimulus category) in turn predicts the level of consolidation across participants. These results elucidate the memory function of sleep in humans and emphasize the importance of SOs and spindles in clocking endogenous consolidation processes.

scholarly journals Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes

2020 ◽  
Author(s):  
Thomas Schreiner ◽  
Marit Petzka ◽  
Tobias Staudigl ◽  
Bernhard P. Staresina
Keyword(s):  
Memory Function ◽  
Nrem Sleep ◽  
Learning Material ◽  
Associative Memories ◽  
Brain Areas ◽  
Slow Oscillations ◽  
Memory Reactivation ◽  
Function Of Sleep ◽  
Prior Experiences

ABSTRACTSleep is thought to support memory consolidation via reactivation of prior experiences, with particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) gating the information flow between relevant brain areas. However, empirical evidence for a role of endogenous memory reactivation (i.e., without experimentally delivered memory cues) for consolidation in humans is lacking. Here, we devised a paradigm in which participants acquired associative memories before taking a nap. Multivariate decoding was then used to capture endogenous memory reactivation during non-rapid eye movement (NREM) sleep. Results revealed reactivation of learning material during SO-spindle complexes, with the precision of SO-spindle coupling predicting reactivation strength. Critically, reactivation strength in turn predicted the level of consolidation across participants. These results elucidate the memory function of sleep in humans and emphasize the importance of SOs and spindles in clocking endogenous consolidation processes.

scholarly journals Targeted memory reactivation in human REM sleep elicits recurrent, temporally compressed reactivation

2021 ◽  
Author(s):  
Mahmoud E. A. Abdellahi ◽  
Anne C. M. Koopman ◽  
Matthias S. Treder ◽  
Penelope A. Lewis
Keyword(s):  
Machine Learning ◽  
Eye Movement ◽  
Performance Improvement ◽  
Rem Sleep ◽  
Strong Evidence ◽  
Nrem Sleep ◽  
Theta Activity ◽  
Rapid Eye Movement ◽  
Memory Reactivation ◽  
Machine Learning Classifiers

AbstractMemories are reactivated during non-rapid eye movement (NREM) sleep, but the question of whether equivalent reactivation also occurs in rapid eye movement (REM) sleep is hotly debated. To examine this, we used a technique called targeted memory reactivation (TMR) in which sounds are paired with learned material in wake, and then re-presented in subsequent sleep to trigger reactivation. We then used machine learning classifiers to identify TMR-induced reactivation in REM. The reactivation we measured was temporally compressed by approximately five times during REM compared to wakeful performance of the task, and often occurred twice after a single TMR cue. Reactivation strength positively predicted overnight performance improvement and was only apparent in trials with high theta activity. These findings provide strong evidence for memory reactivation in human REM sleep after TMR as well as an initial characterisation of this reactivation.

scholarly journals Local Targeted Memory Reactivation in Human Sleep

2019 ◽  
Author(s):  
Ella Bar ◽  
Anat Arzi ◽  
Ofer Perl ◽  
Ethan Livne ◽  
Noam Sobel ◽  
...  
Keyword(s):  
Slow Wave ◽  
Visual Fields ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Functional Neuroanatomy ◽  
Memory Reactivation ◽  
Odor Cues ◽  
Human Sleep ◽  
Global Action ◽  
Local Sleep

AbstractMemory consolidation can be promoted via Targeted Memory Reactivation (TMR) that re-presents training cues or context during sleep. Whether TMR acts locally or globally on cortical sleep oscillations remains unknown. Here we exploit the unique functional neuroanatomy of olfaction with its ipsilateral stimulus processing to perform local TMR in one brain hemisphere. Participants learned associations between words and locations in left or right visual fields with contextual odor throughout. During post-learning naps, odors were presented to one nostril throughout NREM sleep. We found improved memory for specific words processed in the cued hemisphere (ipsilateral to stimulated nostril). Unilateral odor cues locally modulated slow wave activity (SWA) such that regional SWA increase in the cued hemisphere negatively correlated with select memories for cued words. Moreover, local TMR improved slow wave-spindle coupling specifically in the cued hemisphere. Thus, TMR in human sleep transcends global action by selectively promoting specific memories associated with local sleep oscillations.

scholarly journals LONG TERM EFFECTS OF CUEING PROCEDURAL MEMORY REACTIVATION DURING NREM SLEEP

NeuroImage ◽  
2021 ◽  
pp. 118573
Author(s):  
Martyna Rakowska ◽  
Mahmoud E.A. Abdellahi ◽  
Paulina Bagrowska ◽  
Miguel Navarrete ◽  
Penelope A. Lewis
Keyword(s):  
Nrem Sleep ◽  
Procedural Memory ◽  
Long Term Effects ◽  
Memory Reactivation

Respiratory Sinus Arrhythmia During Sleep and Waking

2019 ◽  
Vol 33 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Elizabeth M. Stoakley ◽  
Karen J. Mathewson ◽  
Louis A. Schmidt ◽  
Kimberly A. Cote
Keyword(s):  
Individual Differences ◽  
Respiratory Sinus Arrhythmia ◽  
Slow Wave Sleep ◽  
Self Regulation ◽  
Nrem Sleep ◽  
Sinus Arrhythmia ◽  
Affective Style ◽  
Waking State ◽  
Optimal Period ◽  
The Stability

Abstract. Resting respiratory sinus arrhythmia (RSA) is related to individual differences in waking affective style and self-regulation. However, little is known about the stability of RSA between sleep/wake stages or the relations between RSA during sleep and waking affective style. We examined resting RSA in 25 healthy undergraduates during the waking state and one night of sleep. Stability of cardiac variables across sleep/wake states was highly reliable within participants. As predicted, greater approach behavior and lower impulsivity were associated with higher RSA; these relations were evident in early night Non-REM (NREM) sleep, particularly in slow wave sleep (SWS). The current research extends previous findings by establishing stability of RSA within individuals between wake and sleep states, and by identifying SWS as an optimal period of measurement for relations between waking affective style and RSA.

Sign in / Sign up

Export Citation Format

Share Document