scholarly journals Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

Cell Reports ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 47-55 ◽  
Author(s):  
Yongliang Wang ◽  
Ali R. Nasiri ◽  
William E. Damsky ◽  
Curtis J. Perry ◽  
Xian-Man Zhang ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Oxidative Phosphorylation ◽  
Tumor Growth ◽  
Murine Models

TSU-68 (SU6668) inhibits local tumor growth and liver metastasis of human colon cancer xenografts via anti-angiogenesis

2005 ◽  
Author(s):  
Kyoko Yorozuya ◽  
Tetsuro Kubota ◽  
Masahiko Watanabe ◽  
Hirotoshi Hasegawa ◽  
Soji Ozawa ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Liver Metastasis ◽  
Tumor Growth ◽  
Human Colon ◽  
Local Tumor ◽  
Human Colon Cancer ◽  
Local Tumor Growth

scholarly journals Silencing long non‑coding RNA, differentiation antagonizing non‑protein coding RNA promotes apoptosis and inhibits tumor growth in colon cancer

2018 ◽  
Author(s):  
Xiao‑Jin Yang ◽  
Jing‑Jing Zhao ◽  
Wei‑Jun Chen ◽  
Gen‑Gen Zhang ◽  
Wei Wang ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Tumor Growth ◽  
Protein Coding ◽  
Non Coding Rna ◽  
Long Non Coding Rna

scholarly journals Review Paper: Implications of the “Cancer Stem Cell” Hypothesis on Murine Models of Colon Cancer and Colitis-associated Cancer

2009 ◽  
Vol 46 (5) ◽  
pp. 819-835 ◽  
Author(s):  
M. J. Hynes ◽  
K. M. Huang ◽  
E. H. Huang
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Murine Models ◽  
New Paradigm ◽  
Cancer Stem Cell Hypothesis ◽  
Molecular Events ◽  
Invaluable Tool ◽  
Relationship Of ◽  
The Relationship

The use of murine models to investigate human diseases has been an invaluable tool. In the areas of inflammation and oncogenesis, such models have provided unique insights into pathogenesis and mechanisms to evaluate potential therapy. As such, one facet of these disease processes links inflammation and cancer. Inflammation is associated with at least 15% of the world's malignancies. One example of this relationship is documented in the association between colitis and colorectal cancer. To date, the precise molecular events linking inflammation and cancer remain unclear. A new paradigm that may bridge these processes includes the cancer stem cell hypothesis. In this review, murine models of colitis, colon cancer, and colitis-associated cancer are discussed in reference to the potential of this paradigm to clarify the relationship of these devastating diseases.

scholarly journals T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth

2017 ◽  
Vol 6 (4) ◽  
pp. e1302631 ◽  
Author(s):  
Else M. Inderberg ◽  
Sébastien Wälchli ◽  
Marit R. Myhre ◽  
Sissel Trachsel ◽  
Hilde Almåsbak ◽  
...  
Keyword(s):  
Colon Cancer ◽  
T Cell ◽  
Cell Therapy ◽  
Tumor Growth ◽  
T Cell Therapy

Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models

Nanoscale ◽  
2022 ◽  
Author(s):  
Aviral Kumar ◽  
Amarnath Singam ◽  
Guruprasadh Swaminathan ◽  
Naresh Killi ◽  
Naveen Kumar Tangudu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Colorectal Cancers ◽  
Murine Models ◽  
Combinatorial Therapy ◽  
Cancer Models ◽  
S 100 ◽  
Eudragit S 100

This novel combination of curcumin (CU)–chitosan (CS) nanocomposites conjugated to Ephb4 shRNA encapsulated with Eudragit S-100 (ES) has been developed to combat breast and colorectal cancers murine models.

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