scholarly journals Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration

Cell Reports ◽  
2018 ◽  
Vol 23 (4) ◽  
pp. 983-992 ◽  
Author(s):  
Lukas Hafner ◽  
Aleksandra Lezaja ◽  
Xu Zhang ◽  
Laure Lemmens ◽  
Maksym Shyian ◽  
...  
2002 ◽  
Vol 32 (2) ◽  
pp. 175-184 ◽  
Author(s):  
Stefan K. Mühlbauer ◽  
Andreas Lössl ◽  
Lilia Tzekova ◽  
Zhurong Zou ◽  

Nature ◽  
2013 ◽  
Vol 503 (7477) ◽  
pp. 544-547 ◽  
Author(s):  
Michelle Hawkins ◽  
Sunir Malla ◽  
Martin J. Blythe ◽  
Conrad A. Nieduszynski ◽  
Thorsten Allers

1985 ◽  
Vol 5 (1) ◽  
pp. 85-92
Author(s):  
L D Spotila ◽  
J A Huberman

We have developed a method which allows determination of the direction in which replication forks move through segments of chromosomal DNA for which cloned probes are available. The method is based on the facts that DNA restriction fragments containing replication forks migrate more slowly through agarose gels than do non-fork-containing fragments and that the extent of retardation of the fork-containing fragments is a function of the extent of replication. The procedure allows the identification of DNA replication origins as sites from which replication forks diverge. In this paper we demonstrate the feasibility of this procedure, with simian virus 40 DNA as a model, and we discuss its applicability to other systems.


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