scholarly journals Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint

Cell Reports ◽  
2018 ◽  
Vol 23 (2) ◽  
pp. 404-414 ◽  
Author(s):  
Ting Wei ◽  
Saman M. Najmi ◽  
Hester Liu ◽  
Karita Peltonen ◽  
Alena Kucerova ◽  
...  
Keyword(s):  
Rna Polymerase ◽  
Small Molecule ◽  
Transcription Elongation ◽  
Rna Polymerase I ◽  
Polymerase I

scholarly journals Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

2010 ◽  
Vol 71 (4) ◽  
pp. 1418-1430 ◽  
Author(s):  
Denis Drygin ◽  
Amy Lin ◽  
Josh Bliesath ◽  
Caroline B. Ho ◽  
Sean E. O'Brien ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Rna Polymerase ◽  
Small Molecule ◽  
Ribosomal Rna ◽  
Solid Tumor ◽  
Rna Synthesis ◽  
Rna Polymerase I ◽  
Solid Tumor Growth ◽  
Polymerase I

scholarly journals Direct Characterization of Transcription Elongation by RNA Polymerase I

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0159527 ◽  
Author(s):  
Suleyman Ucuncuoglu ◽  
Krysta L. Engel ◽  
Prashant K. Purohit ◽  
David D. Dunlap ◽  
David A. Schneider ◽  
...  
Keyword(s):  
Rna Polymerase ◽  
Transcription Elongation ◽  
Rna Polymerase I ◽  
Polymerase I

scholarly journals A Novel Assay for RNA Polymerase I Transcription Elongation Sheds Light on the Evolutionary Divergence of Eukaryotic RNA Polymerases

Biochemistry ◽  
2019 ◽  
Vol 58 (16) ◽  
pp. 2116-2124 ◽  
Author(s):  
Catherine E. Scull ◽  
Zachariah M. Ingram ◽  
Aaron L. Lucius ◽  
David A. Schneider
Keyword(s):  
Rna Polymerase ◽  
Transcription Elongation ◽  
Rna Polymerases ◽  
Rna Polymerase I ◽  
Evolutionary Divergence ◽  
Polymerase I

scholarly journals Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress

2014 ◽  
Vol 13 (11) ◽  
pp. 2537-2546 ◽  
Author(s):  
Karita Peltonen ◽  
Laureen Colis ◽  
Hester Liu ◽  
Sari Jäämaa ◽  
Zhewei Zhang ◽  
...  
Keyword(s):  
Rna Polymerase ◽  
Small Molecule ◽  
Rna Polymerase I ◽  
Nucleolar Stress ◽  
Polymerase I
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