scholarly journals Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells

2016 ◽  
Vol 28 (4) ◽  
pp. 325-334 ◽  
Author(s):  
Md. Mostafizur Rahman ◽  
Nowshin N. Rumzhum ◽  
Philip M. Hansbro ◽  
Jonathan C. Morris ◽  
Andrew R. Clark ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Protein Phosphatase ◽  
Protein Phosphatase 2A ◽  
Lung Epithelial Cells ◽  
Lung Epithelial ◽  
Phosphatase 2A ◽  
Anti Inflammatory ◽  
A549 Lung

scholarly journals TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators

2016 ◽  
Vol 78 ◽  
pp. 279-287 ◽  
Author(s):  
Md. Mostafizur Rahman ◽  
Pavan Prabhala ◽  
Nowshin N. Rumzhum ◽  
Brijeshkumar S. Patel ◽  
Thomas Wickop ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Lung Epithelial Cells ◽  
Lung Epithelial ◽  
Anti Inflammatory ◽  
A549 Lung

scholarly journals The Inflammatory Regulation of TRPA1 Expression in Human A549 Lung Epithelial Cells

2021 ◽  
pp. 102059
Author(s):  
Samu Luostarinen ◽  
Mari Hämäläinen ◽  
Noriyuki Hatano ◽  
Katsuhiko Muraki ◽  
Eeva Moilanen
Keyword(s):  
Epithelial Cells ◽  
Lung Epithelial Cells ◽  
Lung Epithelial ◽  
Inflammatory Regulation ◽  
Human A549 ◽  
A549 Lung

Silica nanoparticles and biological dispersants: genotoxic effects on A549 lung epithelial cells

2015 ◽  
Vol 17 (10) ◽  
Author(s):  
David M. Brown ◽  
Julia Varet ◽  
Helinor Johnston ◽  
Alison Chrystie ◽  
Vicki Stone
Keyword(s):  
Epithelial Cells ◽  
Silica Nanoparticles ◽  
Lung Epithelial Cells ◽  
Genotoxic Effects ◽  
Lung Epithelial ◽  
A549 Lung

scholarly journals Galectin-3 is essential for IgE-dependent activation of human basophils by A549 lung epithelial cells

2019 ◽  
Vol 144 (1) ◽  
pp. 312-315.e1 ◽  
Author(s):  
John T. Schroeder ◽  
Abiodun A. Adeosun ◽  
Danh Do ◽  
Anja P. Bieneman
Keyword(s):  
Epithelial Cells ◽  
Lung Epithelial Cells ◽  
Lung Epithelial ◽  
Galectin 3 ◽  
Human Basophils ◽  
A549 Lung

scholarly journals Cytotoxic Effects of Air Freshener Biocides in Lung Epithelial Cells

2013 ◽  
Vol 8 (9) ◽  
pp. 1934578X1300800
Author(s):  
Jung-Taek Kwon ◽  
Mimi Lee ◽  
Gun-Baek Seo ◽  
Hyun-Mi Kim ◽  
Ilseob Shim ◽  
...  
Keyword(s):  
Dna Damage ◽  
Epithelial Cells ◽  
Cell Viability ◽  
Lung Epithelial Cells ◽  
Ros Generation ◽  
Dependent Manner ◽  
Cytotoxic Effects ◽  
Lung Epithelial ◽  
Dose Dependent ◽  
A549 Lung

This study evaluated the cytotoxicity of mixtures of citral (CTR) and either benzisothiazolinone (BIT, Mix-CTR-BIT) or triclosan (TCS, Mix-CTR-TCS) in human A549 lung epithelial cells. We investigated the effects of various mix ratios of these common air freshener ingredients on cell viability, cell proliferation, reactive oxygen species (ROS) generation, and DNA damage. Mix-CTR-BIT and Mix-CTR-TCS significantly decreased the viability of lung epithelial cells and inhibited cell growth in a dose-dependent manner. In addition, both mixtures increased ROS generation, compared to that observed in control cells. In particular, cell viability, growth, and morphology were affected upon increase in the proportion of BIT or TCS in the mixture. However, comet analysis showed that treatment of cells with Mix-CTR-BIT or Mix-CTR-TCS did not increase DNA damage. Taken together, these data suggested that increasing the content of biocides in air fresheners might induce cytotoxicity, and that screening these compounds using lung epithelial cells may contribute to hazard assessment.

POTENTIATION OF FAS- AND TRAIL-MEDIATED APOPTOSIS BY IFN-γ IN A549 LUNG EPITHELIAL CELLS: ENHANCEMENT OF CASPASE-8 EXPRESSION THROUGH IFN-RESPONSE ELEMENT

Cytokine ◽  
2002 ◽  
Vol 20 (6) ◽  
pp. 283-288 ◽  
Author(s):  
Ki-Bae Kim ◽  
Yun-Hee Choi ◽  
In-Ki Kim ◽  
Chul-Woong Chung ◽  
Byung Ju Kim ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Lung Epithelial Cells ◽  
Caspase 8 ◽  
Response Element ◽  
Lung Epithelial ◽  
Ifn Γ ◽  
A549 Lung

scholarly journals Annexin-A1 promotes RIG-I-dependent signaling and apoptosis via regulation of the IRF3–IFNAR–STAT1–IFIT1 pathway in A549 lung epithelial cells

2020 ◽  
Vol 11 (6) ◽  
Author(s):  
Gracemary L. R. Yap ◽  
Karishma Sachaphibulkij ◽  
Sok Lin Foo ◽  
Jianzhou Cui ◽  
Anna-Marie Fairhurst ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Lung Epithelial Cells ◽  
Annexin A1 ◽  
Lung Epithelial ◽  
A549 Lung
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