Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Martin Enge; H. Efsun Arda; Marco Mignardi; John Beausang; Rita Bottino; Seung K. Kim; Stephen R. Quake

doi:10.1016/j.cell.2017.09.004

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Cell ◽

10.1016/j.cell.2017.09.004 ◽

2017 ◽

Vol 171 (2) ◽

pp. 321-330.e14 ◽

Cited By ~ 169

Author(s):

Martin Enge ◽

H. Efsun Arda ◽

Marco Mignardi ◽

John Beausang ◽

Rita Bottino ◽

...

Keyword(s):

Single Cell ◽

Somatic Mutation ◽

Single Cell Analysis ◽

Human Pancreas ◽

Cell Analysis

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Faculty Opinions recommendation of Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.731389434.793537519 ◽

2017 ◽

Author(s):

Lucio Nitsch

Keyword(s):

Single Cell ◽

Somatic Mutation ◽

Single Cell Analysis ◽

Human Pancreas ◽

Cell Analysis

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Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers

Journal of Clinical Investigation ◽

10.1172/jci148113 ◽

2022 ◽

Author(s):

Shixiang Sun ◽

Kristina Brazhnik ◽

Moonsook Lee ◽

Alexander Y. Maslov ◽

Yi Zhang ◽

...

Keyword(s):

Epithelial Cells ◽

Single Cell ◽

Somatic Mutation ◽

Single Cell Analysis ◽

Mammary Epithelial Cells ◽

Mammary Epithelial ◽

Cell Analysis ◽

Mutation Carriers ◽

Mutation Burden

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An Erratum for the Research Article: “Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver” by K. Brazhnik, S. Sun, O. Alani, M. Kinkhabwala, A. W. Wolkoff, A. Y. Maslov, X. Dong, and J. Vijg

Science Advances ◽

10.1126/sciadv.abe8055 ◽

2020 ◽

Vol 6 (40) ◽

pp. eabe8055

Keyword(s):

Single Cell ◽

Somatic Mutation ◽

Human Liver ◽

Single Cell Analysis ◽

Cell Analysis ◽

Differentiated Cells ◽

Research Article ◽

Age Related

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Molecular single cell analysis reveals that human CD5-positive B cells are characterized by rearranged V genes lacking somatic mutation

Immunology Letters ◽

10.1016/s0165-2478(97)85051-1 ◽

1997 ◽

Vol 56 ◽

pp. 13

Author(s):

M. Fischer ◽

U. Klein ◽

R. Küppers

Keyword(s):

B Cells ◽

Single Cell ◽

Somatic Mutation ◽

Single Cell Analysis ◽

Cell Analysis ◽

V Genes

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Molecular single cell analysis reveals that human CD5-positive B cells are characterized by rearranged V genes lacking somatic mutation

Immunology Letters ◽

10.1016/s0165-2478(97)86889-7 ◽

1997 ◽

Vol 56 (1-3) ◽

pp. 13

Author(s):

M Fischer

Keyword(s):

B Cells ◽

Single Cell ◽

Somatic Mutation ◽

Single Cell Analysis ◽

Cell Analysis ◽

V Genes

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Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.

Journal of Clinical Investigation ◽

10.1172/jci119691 ◽

1997 ◽

Vol 100 (7) ◽

pp. 1667-1676 ◽

Cited By ~ 45

Author(s):

M Fischer ◽

U Klein ◽

R Küppers

Keyword(s):

B Cells ◽

Single Cell ◽

Somatic Mutation ◽

Peripheral Blood ◽

Single Cell Analysis ◽

Cell Analysis ◽

Healthy Humans

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Review for "Immunocyte single cell analysis of vaccine‐induced narcolepsy"

10.1002/eji.202048633/v2/review2 ◽

2020 ◽

Keyword(s):

Single Cell ◽

Single Cell Analysis ◽

Cell Analysis

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Author response for "Immunocyte single cell analysis of vaccine‐induced narcolepsy"

10.1002/eji.202048633/v2/response1 ◽

2020 ◽

Author(s):

Alexander Lind ◽

Falastin Salami ◽

Anne‐Marie Landtblom ◽

Lars Palm ◽

Åke Lernmark ◽

...

Keyword(s):

Single Cell ◽

Single Cell Analysis ◽

Author Response ◽

Cell Analysis

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Faculty Opinions recommendation of Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1366959.838057 ◽

2010 ◽

Author(s):

Avinash Bhandoola

Keyword(s):

Single Cell ◽

Single Cell Analysis ◽

Molecular Heterogeneity ◽

Cell Analysis ◽

The Common ◽

Progenitor Compartment

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Faculty Opinions recommendation of A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13709958.15123059 ◽

2012 ◽

Author(s):

Bart Roep ◽

Menno van Lummel

Keyword(s):

T Cell ◽

Single Cell ◽

High Throughput ◽

Single Cell Analysis ◽

Cd8 T Cell ◽

Cytokine Secretion ◽

Cell Analysis ◽

Cell Functions

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