scholarly journals Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo

Cell ◽  
2016 ◽  
Vol 165 (1) ◽  
pp. 75-87 ◽  
Author(s):  
Melanie D. White ◽  
Juan F. Angiolini ◽  
Yanina D. Alvarez ◽  
Gurpreet Kaur ◽  
Ziqing W. Zhao ◽  
...  
Keyword(s):  
Cell Fate ◽  
Mouse Embryo ◽  
Cell Mouse Embryo

scholarly journals Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo

2017 ◽  
Vol 145 ◽  
pp. S135
Author(s):  
Stephanie Bissiere ◽  
Melanie White ◽  
Yanina Alvarez ◽  
Winston Ziqing Zhao ◽  
Jennifer Zenker ◽  
...  
Keyword(s):  
Cell Fate ◽  
Mouse Embryo ◽  
Cell Mouse Embryo

Reporter Gene Expression in G2 of the 1-Cell Mouse Embryo

1993 ◽  
Vol 156 (2) ◽  
pp. 552-556 ◽  
Author(s):  
Prahlad T. Ram ◽  
Richard M. Schultz
Keyword(s):  
Gene Expression ◽  
Reporter Gene ◽  
Mouse Embryo ◽  
Reporter Gene Expression ◽  
Cell Mouse Embryo

Evidence for expression of the paternal genome in the two-cell mouse embryo

Nature ◽  
1981 ◽  
Vol 294 (5840) ◽  
pp. 450-451 ◽  
Author(s):  
Janet A. Sawicki ◽  
Terry Magnuson ◽  
Charles J. Epstein
Keyword(s):  
Mouse Embryo ◽  
Paternal Genome ◽  
Cell Mouse Embryo

Estimation of Isotonic Point of Incubation Medium For Two-Cell Mouse Embryo

2011 ◽  
Vol 152 (1) ◽  
pp. 142-145 ◽  
Author(s):  
M. A. Pogorelova ◽  
V. A. Golichenkov ◽  
V. N. Pogorelova ◽  
E. V. Kornienko ◽  
A. I. Panait ◽  
...  
Keyword(s):  
Mouse Embryo ◽  
Incubation Medium ◽  
Cell Mouse Embryo

Apparent absence of antiport activity in the two-cell mouse embryo

1990 ◽  
Vol 138 (2) ◽  
pp. 421-429 ◽  
Author(s):  
Jay M. Baltz ◽  
John D. Biggers ◽  
Claude Lechene
Keyword(s):  
Mouse Embryo ◽  
Apparent Absence ◽  
Cell Mouse Embryo

The distribution of ingested horseradish peroxidase in the 16-cell mouse embryo

Development ◽  
1981 ◽  
Vol 66 (1) ◽  
pp. 191-207
Author(s):  
W. J. D. Reeve
Keyword(s):  
Horseradish Peroxidase ◽  
Mouse Embryo ◽  
Single Cells ◽  
Fluorescent Antibody ◽  
Surface Binding ◽  
Cytoplasmic Organization ◽  
Cell Embryo ◽  
Polarized Surface ◽  
Cell Mouse Embryo

Cells of the 16-cell mouse embryo endocytose horseradish peroxidase (HRP) which becomes localized in most cases to a juxtanuclear position. Cells that have ingested HRP in intact embryos, and cells dissociated from embryos prior to culture in HRP, showed similar patterns of cytoplasmic distribution of the ingested enzyme. Cells in the embryo in situ were incubated in HRP, and then labelled with fluorescent antibody either before (to label the outside surface of the embryo) or after (to reveal populations of outer polar and inner apolar cells) their disaggregation into single cells. The population of polar outside cells from the morula includes more cells with a highly restricted localization of HRPcontaining vesicles than does the population of inside cells, and this restricted localization underlies the exposed surface or pole of the cell. A 2/16 couplet formed by division in vitro of a 1/8 cell is comparable to the pairs of cells dissociated from 16-cell embryos; most couplets from either source consisted of a larger cell that showed polarized surface binding of fluorescent ligand (fluorescent pole) and a smaller cell with a uniform distribution of bound ligand. The incidence of restricted patterns of HRP staining was highest among populations of both larger and polar cells. When 1/8 cells labelled with HRP are observed during division to 2/16, the previously clustered vesicles of ingested HRP become more dispersed throughout the cytoplasm and, although the two cells of some couplets can stain differently very soon after their formation, the patterns of distribution of HRP take about 1 h after division to stabilize. These observations are consistent with cells of the 16-cell embryo inheriting different features of cytoplasmic organization.

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