Frozen images of a cool channel with icy compounds

Cell Calcium ◽  
2019 ◽  
Vol 80 ◽  
pp. 189-191
Author(s):  
Thomas Voets
Keyword(s):  
Cool Channel

A Cool Channel in Cold Transduction

Physiology ◽  
2011 ◽  
Vol 26 (4) ◽  
pp. 273-285 ◽  
Author(s):  
Ramón Latorre ◽  
Sebastián Brauchi ◽  
Rodolfo Madrid ◽  
Patricio Orio
Keyword(s):  
Membrane Trafficking ◽  
Transient Receptor Potential ◽  
Somatosensory System ◽  
Physiological Role ◽  
Receptor Potential ◽  
Molecular Entity ◽  
Cool Channel ◽  
Cold Temperatures ◽  
Transient Receptor Potential Melastatin ◽  
Transient Receptor

Transient receptor potential melastatin 8 (TRPM8), a calcium-permeable cation channel activated by cold, cooling compounds and voltage, is the main molecular entity responsible for detection of cold temperatures in the somatosensory system. Here, we review the biophysical properties, physiological role, and near-membrane trafficking of this exciting polymodal ion channel.

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