The transcriptional regulatory code of eukaryotic cells – insights from genome-wide analysis of chromatin organization and transcription factor binding

2006 ◽  
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Bing Ren
Blood ◽  
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Julie A. I. Thoms ◽  
Dilmi Perera ◽  
Judith Schütte ◽  
Ashwin Unnikrishnan ◽  
...  

Key Points Genome-wide binding profiles of FLI1, ERG, GATA2, RUNX1, SCL, LMO2, and LYL1 in human HSPCs reveals patterns of combinatorial TF binding. Integrative analysis of transcription factor binding reveals a densely interconnected network of coding and noncoding genes in human HSPCs.


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David S Johnson ◽  
Andreas Sundquist ◽  
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PLoS ONE ◽  
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Arnaud Droit ◽  
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Gordon Robertson ◽  
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...  

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