scholarly journals Occupational exposure to heavy metals, alcohol intake, and risk of type 2 diabetes and prediabetes among Chinese male workers

2019 ◽  
Vol 5 (2) ◽  
pp. 97-104 ◽  
Author(s):  
Ai-Min Yang ◽  
Xiao-Bin Hu ◽  
Simin Liu ◽  
Ning Cheng ◽  
De-Sheng Zhang ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Type 2 Diabetes ◽  
Occupational Exposure ◽  
Alcohol Intake ◽  
Chinese Male ◽  
Male Workers

scholarly journals Relationship between heavy metal exposure and type 2 diabetes: a large-scale retrospective cohort study using occupational health examinations

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e039541
Author(s):  
Jun Ho Ji ◽  
Mi Hyeon Jin ◽  
Jung-Hun Kang ◽  
Soon Il Lee ◽  
Suee Lee ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Type 2 Diabetes ◽  
Heavy Metal ◽  
Cohort Study ◽  
Retrospective Cohort ◽  
Metal Exposure ◽  
Heavy Metal Exposure ◽  
Lead And Cadmium

ObjectivesTo investigate the associations between heavy metal exposure and serum ferritin levels, physical measurements and type 2 diabetes mellitus (DM).DesignA retrospective cohort study.SettingChangwon, the location of this study, is a Korean representative industrial city. Data were obtained from medical check-ups between 2002 and 2018.ParticipantsA total of 34 814 male subjects were included. Of them, 1035 subjects with lead exposure, 200 subjects with cadmium exposure and the 33 579 remaining were assigned to cohort A, cohort B and the control cohort, respectively. Data including personal history of alcohol and smoking, age, height, weight, the follow-up duration, haemoglobin A1c (HbA1c), fasting blood sugar (FBS), ferritin levels, and lead and cadmium levels within 1 year after exposure were collected.Primary outcome measureIn subjects without diabetes, changes in FBS and HbA1c were analysed through repeated tests at intervals of 1 year or longer after the occupational exposure to heavy metals.ResultsIn Cohort A, DM was diagnosed in 33 subjects. There was a significant difference in lead concentrations between the subjects diagnosed with DM and those without DM during the follow-up period (3.94±2.92 mg/dL vs 2.81±2.03 mg/dL, p=0.002). Simple exposure to heavy metals (lead and cadmium) was not associated with DM in Cox regression models (lead exposure (HR) 1.01, 95% CI: 0.58 to 1.77, p 0.971; cadmium exposure HR 1.48, 95% CI: 0.61 to 3.55, p=0.385). Annual changes in FBS according to lead concentration at the beginning of exposure showed a positive correlation (r=0.072, p=0.032).ConclusionOur findings demonstrated that simple occupational exposure to heavy metals lead and cadmium was not associated with the incidence of DM. However, lead concentrations at the beginning of the exposure might be an indicator of DM and glucose elevations.

Diet and diabetes - part 2

2007 ◽  
Vol 286 ◽  
pp. 1-3
Keyword(s):  
Type 2 Diabetes ◽  
Glucose Control ◽  
Alcohol Intake ◽  
Dietary Advice ◽  
Lifestyle Interventions ◽  
Long Term Outcomes ◽  
Short Term ◽  
Diet And Diabetes

In a nutshellDietary advice for diabetics has included both reducing and increasing CHO.Some short term trials show improved glucose control from lower CHO, more fibre and lower GI foods. Light alcohol intake may provide some benefit. All these require further trials on their long term outcomes. And we should remember that, of all the lifestyle interventions in type 2 diabetes, the most effective appears to be exercise.

scholarly journals Establishing links between alcohol intake, cognitive functions and type 2 diabetes

2014 ◽  
Vol 66 (2) ◽  
pp. 811-817
Author(s):  
Cristina Toarba ◽  
Simona Hogas ◽  
Adrian Covic ◽  
Manuela Padurariu ◽  
Alin Ciobica ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Alcohol Consumption ◽  
Cognitive Functions ◽  
Alcohol Intake ◽  
Mmse Score ◽  
Present Report ◽  
Cognitive Testing ◽  
Or Groups ◽  
Higher Doses

In the present report, we studied the associations that might exist between alcohol consumption, cognitive functions and diabetic pathology in patients with type 2 diabetes (T2D). The alcohol intake of 219 patients diagnosed with diabetes was classified into 6 groups: nondrinkers, 0.1-9.9, 10.0-14.9, 15.0-29.9, 30.0-49.9 and ? 50.0, according to the total amount (grams/day) of alcohol consumption. Our results mainly confirm that moderate alcohol consumption can reduce some of the neuropathological aspects of T2D, as demonstrated by the decrease in glycemic levels in patients that consumed higher levels of alcohol (30.0-49.9 g/day), when compared to non-drinkers (p=0.04) or groups in which individuals consumed 0.1-9.9 g/day (p=0.01) and 10.0-14.9 g/day (p=0.02). Regarding the results of cognitive testing, we noticed a significant increase in the values of the MMSE score a lower dose of alcohol intake (0.1-9.9 g/day) was compared with higher doses: 30.0-49.9 g/day (p=0.008) and ? 50.0 g/day (p=0.047).

scholarly journals Coffee, tea, and alcohol intake in relation to risk of type 2 diabetes in African American women

2010 ◽  
Vol 92 (4) ◽  
pp. 960-966 ◽  
Author(s):  
Deborah A Boggs ◽  
Lynn Rosenberg ◽  
Edward A Ruiz-Narvaez ◽  
Julie R Palmer
Keyword(s):  
Type 2 Diabetes ◽  
African American ◽  
African American Women ◽  
Alcohol Intake ◽  
American Women

PP119-MON EFFECT OF MODERATE ALCOHOL INTAKE ON 24-H BLOOD PRESSURE DYNAMICS AMONG PATIENTS WITH TYPE 2 DIABETES

2013 ◽  
Vol 32 ◽  
pp. S166
Author(s):  
Y. Gepner ◽  
D. Schwarzfuchs ◽  
R. Golan ◽  
Y. Henkin ◽  
I. Harman-Boehm ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Alcohol Intake ◽  
Pressure Dynamics ◽  
Moderate Alcohol Intake

scholarly journals Alcohol and the risk for latent autoimmune diabetes in adults: results based on Swedish ESTRID study

2014 ◽  
Vol 171 (5) ◽  
pp. 535-543 ◽  
Author(s):  
Bahareh Rasouli ◽  
Tomas Andersson ◽  
Per-Ola Carlsson ◽  
Mozhgan Dorkhan ◽  
Valdemar Grill ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Alcohol Consumption ◽  
Alcohol Intake ◽  
Case Control Study ◽  
Autoimmune Diabetes ◽  
Case Control ◽  
Latent Autoimmune Diabetes ◽  
Incident Cases ◽  
Control Study

ObjectiveModerate alcohol consumption is associated with a reduced risk of type 2 diabetes. Our aim was to investigate whether alcohol consumption is associated with the risk of latent autoimmune diabetes in adults (LADA), an autoimmune form of diabetes with features of type 2 diabetes.DesignA population-based case–control study was carried out to investigate the association of alcohol consumption and the risk of LADA.MethodsWe used data from the ESTRID case–control study carried out between 2010 and 2013, including 250 incident cases of LADA (glutamic acid decarboxylase antibodies (GADAs) positive) and 764 cases of type 2 diabetes (GADA negative), and 1012 randomly selected controls aged ≥35. Logistic regression was used to estimate the odds ratios (ORs) of diabetes in relation to alcohol intake, adjusted for age, sex, BMI, family history of diabetes, smoking, and education.ResultsAlcohol consumption was inversely associated with the risk of type 2 diabetes (OR 0.95, 95% CI 0.92–0.99 for every 5-g increment in daily intake). Similar results were observed for LADA, but stratification by median GADA levels revealed that the results only pertained to LADA with low GADA levels (OR 0.85, 95% CI 0.76–0.94/5 g alcohol per day), whereas no association was observed with LADA having high GADA levels (OR 1.00, 95% CI 0.94–1.06/5 g per day). Every 5-g increment of daily alcohol intake was associated with a 10% increase in GADA levels (P=0.0312), and a 10% reduction in homeostasis model assessment of insulin resistance (P=0.0418).ConclusionsOur findings indicate that alcohol intake may reduce the risk of type 2 diabetes and type 2-like LADA, but has no beneficial effects on diabetes-related autoimmunity.

Alcohol intake, consumption pattern and beverage type, and the risk of Type 2 diabetes

2006 ◽  
Vol 23 (6) ◽  
pp. 690-697 ◽  
Author(s):  
A. M. Hodge ◽  
D. R. English ◽  
K. O'Dea ◽  
G. G. Giles
Keyword(s):  
Type 2 Diabetes ◽  
Alcohol Intake ◽  
Consumption Pattern ◽  
Beverage Type
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