Cetyltrimethylammonium bromide-gold nanoparticles composite modified pencil graphite electrode for the electrochemical investigation of cefixime present in pharmaceutical formulations and biology

2019 ◽  
Vol 21 ◽  
pp. 100217 ◽  
Author(s):  
P. Manjunatha ◽  
Y. Arthoba Nayaka
Keyword(s):  
Gold Nanoparticles ◽  
Cetyltrimethylammonium Bromide ◽  
Graphite Electrode ◽  
Pharmaceutical Formulations ◽  
Pencil Graphite Electrode ◽  
Electrochemical Investigation

Disposable Pencil Graphite Electrode for Ciprofloxacin Determination in Pharmaceutical Formulations by Square Wave Voltammetry

2020 ◽  
Author(s):  
Guilherme Figueira Alves ◽  
Thalles Pedrosa Lisboa ◽  
Lucas Vinícius Faria ◽  
Davi Marques Farias ◽  
Maria Auxiliadora Costa Matos ◽  
...  
Keyword(s):  
Square Wave Voltammetry ◽  
Graphite Electrode ◽  
Pharmaceutical Formulations ◽  
Pencil Graphite Electrode ◽  
Square Wave ◽  
Wave Voltammetry

scholarly journals Novel Competitive Voltammetric Aptasensor Based on Electrospun Carbon Nanofibers-Gold Nanoparticles Modified Graphite Electrode for Salmonella enterica serovar Detection

2020 ◽  
Vol 11 (2) ◽  
pp. 8702-8715
Keyword(s):  
Gold Nanoparticles ◽  
Carbon Nanofibers ◽  
Electrochemical Detection ◽  
Salmonella Enterica ◽  
Electrochemical Impedance ◽  
Graphite Electrode ◽  
Limit Of Detection ◽  
Differential Pulse ◽  
Pencil Graphite Electrode ◽  
Experimental Conditions

Salmonella enterica is considered one of the most common bacterial agent causes of acute gastroenteritis and foodborne illness in humans worldwide. Antibiotic-resistant is considered as a major problem in Salmonella enterica Serovar. This study introduces a new simple and sensitive aptasensor based on chitosan (Chi)-electrospun carbon nanofibers (CNF) /gold nanoparticles (GNPs) decorated pencil graphite electrode (GE) as a novel platform for electrochemical detection of Salmonella enterica Serovar. A Salmonella-specific recognition aptamer ssDNA sequence was used in the development of this voltammetric biosensor. Electrochemical behaviors of electrodes; unmodified GE, CNF-Chi/GE, GNPs/CNF-Chi/GE, GNPs/CNF-Chi/GEs linked with the aptamer were studied by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). After the optimization of experimental conditions (e.g., CNF concentration, pH, and incubation time), electrochemical detection of Salmonella was performed via differential pulse voltammetry (DPV) in methylene blue solution. The designed aptasensor exhibited a linear range of 10 to 105 (CFU/mL) with the limit of detection (LOD) 1.223 (Cfu/mL) for Salmonella. This aptasensor displayed excellent selectivity and remarkable sensitivity in terms of the detection of Salmonella enterica even in the real samples as compared to the polymerase chain reaction (PCR) technique. The constructed aptasensor is a highly sensitive sensor for the detection of Salmonella enterica and also can be tailored for various other targets.

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