A new adaptive design based on Simon's two-stage optimal design for phase II clinical trials

2012 ◽  
Vol 33 (6) ◽  
pp. 1255-1260 ◽  
Author(s):  
Hua Jin ◽  
Zhen Wei
Keyword(s):  
Clinical Trials ◽  
Optimal Design ◽  
Phase Ii ◽  
Adaptive Design ◽  
Two Stage ◽  
Phase Ii Clinical Trials

Optimal Two-Stage Designs Allowing Flexibility in Number of Subjects for Phase II Clinical Trials

2009 ◽  
Vol 19 (4) ◽  
pp. 721-731 ◽  
Author(s):  
Nobuyuki Masaki ◽  
Tatsuki Koyama ◽  
Isao Yoshimura ◽  
Chikuma Hamada
Keyword(s):  
Clinical Trials ◽  
Phase Ii ◽  
Two Stage ◽  
Phase Ii Clinical Trials

Adaptive two-stage designs in phase II clinical trials

2006 ◽  
Vol 25 (19) ◽  
pp. 3382-3395 ◽  
Author(s):  
Anindita Banerjee ◽  
Anastasios A. Tsiatis
Keyword(s):  
Clinical Trials ◽  
Phase Ii ◽  
Two Stage ◽  
Phase Ii Clinical Trials

Bayesian adaptive two-stage design for determining person-time in Phase II clinical trials with Poisson data

2016 ◽  
Vol 43 (9) ◽  
pp. 1625-1635 ◽  
Author(s):  
Austin L. Hand ◽  
John A. Scott ◽  
Phil D. Young ◽  
James D. Stamey ◽  
Dean M. Young
Keyword(s):  
Clinical Trials ◽  
Phase Ii ◽  
Two Stage ◽  
Stage Design ◽  
Phase Ii Clinical Trials ◽  
Two Stage Design ◽  
Poisson Data
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