Respiratory adverse event profiles in cystic fibrosis placebo subjects in short- and long-term inhaled therapy trials

2006 ◽  
Vol 27 (6) ◽  
pp. 561-570 ◽  
Author(s):  
Heidi Sucharew ◽  
Christopher H. Goss ◽  
Steven P. Millard ◽  
Bonnie W. Ramsey
Keyword(s):  
Cystic Fibrosis ◽  
Adverse Event ◽  
Inhaled Therapy ◽  
Short And Long Term

scholarly journals The short and long term effects of exercise training in non-cystic fibrosis bronchiectasis – a randomised controlled trial

2014 ◽  
Vol 15 (1) ◽  
pp. 44 ◽  
Author(s):  
Annemarie L Lee ◽  
Catherine J Hill ◽  
Nola Cecins ◽  
Sue Jenkins ◽  
Christine F McDonald ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Randomised Controlled Trial ◽  
Exercise Training ◽  
Controlled Trial ◽  
Long Term Effects ◽  
Short And Long Term ◽  
Randomised Controlled

scholarly journals RNASeq Based Transcriptional Profiling of Pseudomonas aeruginosa PA14 after Short- and Long-Term Anoxic Cultivation in Synthetic Cystic Fibrosis Sputum Medium

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0147811 ◽  
Author(s):  
Muralidhar Tata ◽  
Michael T. Wolfinger ◽  
Fabian Amman ◽  
Nicole Roschanski ◽  
Andreas Dötsch ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pseudomonas Aeruginosa ◽  
Transcriptional Profiling ◽  
Cystic Fibrosis Sputum ◽  
Short And Long Term

scholarly journals Very High Sputum Cyanide Concentrations during Acute Pulmonary Exacerbations in Cystic Fibrosis Patients

2021 ◽  
Author(s):  
Daniel Guck ◽  
David Kim ◽  
Brian Logue ◽  
Nesta Bortey-Sam ◽  
Nicole Tubbs ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Specific Treatment ◽  
Mitochondrial Activity ◽  
Free Cyanide ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Data Support ◽  
Short And Long Term ◽  
Very High

Abstract Background: Cyanide (CN) has been shown to be chronically present in the airways of cystic fibrosis (CF) patients, as a byproduct Pseudomonas’ metabolism. We sought to determine the concentrations of CN in the sputum of CF patients, who were admitted to the hospital with acute clinical exacerbations using 2 different approaches. Methods: Sputum was collected within 1 day (median) of admission and immediately analyzed for the presence of total and free CN. Results: We found 1) toxic levels of CN in the sputum of our patients, ranging from 27 to 401 µM, 2) the majority of the cyanide was in the form of free, thus diffusible, CN and 3) no cyanide in the blood. Conclusions: While the chronic presence of CN in patients colonized with pseudomonas is not a new concept, the present data support the view that very high levels of free cyanide are present in the airways of CF patients during an acute clinical exacerbation, i.e. levels compatible with concentrations of CN able to virtually stop the mitochondrial activity. It becomes therefore urgent to investigate whether, in CF patients, cyanide is a significant factor affecting the short and long-term outcome and whether a specific treatment of CN intoxication of the airways is warranted during an exacerbation.

scholarly journals Validation of short- and long-term demographic forecasts using the Canadian Cystic Fibrosis Registry

2019 ◽  
Vol 55 (1) ◽  
pp. 1901667
Author(s):  
Vanessa Martelli ◽  
Jenna Sykes ◽  
Pierre-Régis Burgel ◽  
Gil Bellis ◽  
Adèle Coriati ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Short And Long Term

Short- and Long-Term Antibiotic Treatment Reduces Airway and Systemic Inflammation in Non–Cystic Fibrosis Bronchiectasis

2012 ◽  
Vol 186 (7) ◽  
pp. 657-665 ◽  
Author(s):  
James D. Chalmers ◽  
Maeve P. Smith ◽  
Brian J. McHugh ◽  
Cathy Doherty ◽  
John R. Govan ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Antibiotic Treatment ◽  
Systemic Inflammation ◽  
Short And Long Term

Short- and Long-Term Results of Total vs Subtotal Thyroid- ectomies in the Surgical Treatment of Graves' Disease

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Nerve Palsy ◽  
Recurrent Laryngeal Nerve Palsy ◽  
Laryngeal Nerve ◽  
Long Term Results ◽  
Graves Disease ◽  
Laryngeal Nerve Palsy ◽  
Short And Long Term

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.

Short- and long-term memory tasks predict working memory performance, and vice versa.

2019 ◽  
Vol 73 (2) ◽  
pp. 79-93 ◽  
Author(s):  
Ian Neath ◽  
Jean Saint-Aubin ◽  
Tamra J. Bireta ◽  
Andrew J. Gabel ◽  
Chelsea G. Hudson ◽  
...  
Keyword(s):  
Working Memory ◽  
Memory Performance ◽  
Long Term Memory ◽  
Term Memory ◽  
Short And Long Term
Sign in / Sign up

Export Citation Format

Share Document