Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease

Andrés Binolfi; Liliana Quintanar; Carlos W. Bertoncini; Christian Griesinger; Claudio O. Fernández

doi:10.1016/j.ccr.2012.05.004

Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease

Coordination Chemistry Reviews ◽

10.1016/j.ccr.2012.05.004 ◽

2012 ◽

Vol 256 (19-20) ◽

pp. 2188-2201 ◽

Cited By ~ 90

Author(s):

Andrés Binolfi ◽

Liliana Quintanar ◽

Carlos W. Bertoncini ◽

Christian Griesinger ◽

Claudio O. Fernández

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Bioinorganic Chemistry ◽

Alpha Synuclein ◽

Copper Coordination

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Bioinorganic Chemistry of Parkinson’s Disease: Structural Determinants for the Copper-Mediated Amyloid Formation of Alpha-Synuclein

Inorganic Chemistry ◽

10.1021/ic1016752 ◽

2010 ◽

Vol 49 (22) ◽

pp. 10668-10679 ◽

Cited By ~ 85

Author(s):

Andrés Binolfi ◽

Esaú E. Rodriguez ◽

Daniela Valensin ◽

Nicola D’Amelio ◽

Emiliano Ippoliti ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Bioinorganic Chemistry ◽

Alpha Synuclein ◽

Amyloid Formation ◽

Structural Determinants

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Conditional control of human wild-type and Parkinson's disease-associated mutant alpha-synuclein in transgenic mouse brain

Aktuelle Neurologie ◽

10.1055/s-2004-833272 ◽

2004 ◽

Vol 31 (S 1) ◽

Author(s):

S Nuber ◽

T Schmidt ◽

D Berg ◽

M Neumann ◽

C Holzmann ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Transgenic Mouse ◽

Mouse Brain ◽

Alpha Synuclein ◽

Wild Type ◽

Conditional Control ◽

Human Wild Type

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Faculty Opinions recommendation of Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1008343.104560 ◽

2002 ◽

Author(s):

John Hardy

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Transgenic Mice ◽

Neurodegenerative Disease ◽

Alpha Synuclein ◽

Alpha Synuclein Aggregation ◽

Familial Parkinson’S Disease

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Faculty Opinions recommendation of Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1010273.149808 ◽

2002 ◽

Author(s):

Harry Ischiropoulos

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein

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Faculty Opinions recommendation of The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13371031.14741147 ◽

2011 ◽

Author(s):

Keith Wilkinson

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein ◽

Drosophila Model

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Faculty Opinions recommendation of Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson's disease brain.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725373935.793530620 ◽

2017 ◽

Author(s):

Vladimir Uversky

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein ◽

Direct Visualization

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Faculty Opinions recommendation of Formation and Implications of Alpha-Synuclein Radical in Maneb- and Paraquat-Induced Models of Parkinson's Disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727495788.793530632 ◽

2017 ◽

Author(s):

Vladimir Uversky

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein

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Faculty Opinions recommendation of Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732415404.793542709 ◽

2018 ◽

Author(s):

Joseph Jankovic ◽

Arjun Tarakad

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein ◽

Endosomal Trafficking

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Faculty Opinions recommendation of Targeting Alpha-Synuclein as a Therapy for Parkinson's Disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737125652.793576733 ◽

2020 ◽

Author(s):

Roger Barker

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein

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Alpha Synuclein Aggregation in a Neurotoxic Model of Parkinson's Disease

10.21236/ada393984 ◽

2000 ◽

Author(s):

Neil W. Kowall

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alpha Synuclein ◽

Alpha Synuclein Aggregation

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