Influence of terminal substituents on the halide anion binding of foldamer-based receptors

2017 ◽  
Vol 28 (8) ◽  
pp. 1659-1662 ◽  
Author(s):  
Ling Yang ◽  
Wei Zhao ◽  
Yan-Ke Che ◽  
Ying Wang ◽  
Hua Jiang
Keyword(s):  
Anion Binding ◽  
Halide Anion

scholarly journals Cationic all-halogen bonding rotaxanes for halide anion recognition

2017 ◽  
Vol 203 ◽  
pp. 245-255 ◽  
Author(s):  
Xiaoxiong Li ◽  
Jason Y. C. Lim ◽  
Paul D. Beer
Keyword(s):  
Halogen Bond ◽  
Anion Recognition ◽  
Halogen Bonding ◽  
Anion Binding ◽  
Halide Anion ◽  
H Nmr ◽  
Organic Solvent Media ◽  
Synthetic Strategy ◽  
Anion Selectivity ◽  
Active Metal

A family of cationic halogen bonding [2]rotaxanes have been synthesised via an active-metal template synthetic strategy. 1H NMR spectroscopic anion titration investigations reveal these interlocked host systems recognize halides selectively over oxoanions in aqueous–organic solvent media. Furthermore, systematically modulating the rigidity and size of the rotaxanes’ anion binding cavities via metal complexation, as well as by varying the number of halogen bond-donor groups in the axle component, was found to dramatically influence halide anion selectivity.

scholarly journals Strong and Selective Halide Anion Binding by Neutral Halogen-Bonding [2]Rotaxanes in Wet Organic Solvents

2017 ◽  
Vol 23 (19) ◽  
pp. 4700-4707 ◽  
Author(s):  
Jason Y. C. Lim ◽  
Thanthapatra Bunchuay ◽  
Paul D. Beer
Keyword(s):  
Organic Solvents ◽  
Halogen Bonding ◽  
Anion Binding ◽  
Halide Anion

Halide anion binding to Gly3, Ala3 and Leu3

2015 ◽  
Vol 377 ◽  
pp. 440-447 ◽  
Author(s):  
Terrence M. Chang ◽  
Giel Berden ◽  
Jos Oomens ◽  
Evan R. Williams
Keyword(s):  
Anion Binding ◽  
Halide Anion

Aryl-triazole foldamers incorporating a pyridinium motif for halide anion binding in aqueous media

2016 ◽  
Vol 52 (24) ◽  
pp. 4505-4508 ◽  
Author(s):  
Jie Shang ◽  
Wei Zhao ◽  
Xichen Li ◽  
Ying Wang ◽  
Hua Jiang
Keyword(s):  
Aqueous Media ◽  
Anion Binding ◽  
Solvent Mixtures ◽  
Halide Anion ◽  
Aqueous Solvent Mixtures ◽  
Aqueous Solvent

Aryl-triazole foldamers incorporating a pyridinium motif are shown to be strongly halide anion binding in aqueous solvent mixtures.

Halide-Anion Binding by Singly and Doubly N-Confused Porphyrins

2006 ◽  
Vol 1 (6) ◽  
pp. 832-844 ◽  
Author(s):  
Hiromitsu Maeda ◽  
Tatsuki Morimoto ◽  
Atsuhiro Osuka ◽  
Hiroyuki Furuta
Keyword(s):  
Anion Binding ◽  
Halide Anion

Unexpected halide anion binding modes in meso-bis-ethynyl picket-calix[4]pyrroles: effects of meso-π (ethynyl) extension

2018 ◽  
Vol 54 (57) ◽  
pp. 7936-7939 ◽  
Author(s):  
Ranjan Dutta ◽  
Dikhi Firmansyah ◽  
Jihoon Kim ◽  
Hongil Jo ◽  
Kang Min Ok ◽  
...  
Keyword(s):  
Anion Binding ◽  
Binding Modes ◽  
Halide Anion

meso-Ethynyl extended aryl-picket calix[4]pyrroles 2 and 3 are designed and synthesized by directly anchoring arylethynyl groups at diametrically opposed meso-positions.

The Ability of Thrombin Inhibitors to Reduce the Thrombin Activity Generated in Plasma on Extrinsic and Intrinsic Activation

1997 ◽  
Vol 77 (03) ◽  
pp. 498-503 ◽  
Author(s):  
D Prasa ◽  
L Svendsen ◽  
J Stürzebecher
Keyword(s):  
Active Site ◽  
Thrombin Generation ◽  
Anion Binding ◽  
Thrombin Inhibitors ◽  
Coagulation System ◽  
Thrombin Activity ◽  
Continuous Registration ◽  
High Concentrations ◽  
20 Nm ◽  
Generation Test

SummaryIn a thrombin generation test with continuous registration of thrombin activity in plasma we studied the ability of a variety of thrombin inhibitors of different type and mechanism of action to influence the activity of thrombin after activation of the coagulation system. Depending on the inhibitor, the peak of thrombin activity is delayed and/or reduced.By blocking the active site of generated thrombin inhibitors cause a concentration dependent reduction of the thrombin peak and inhibit feed-back reactions of thrombin resulting in a delay of thrombin generation. Highly potent synthetic active-site directed inhibitors (Ki ≤ 20 nM) reduce the thrombin activity formed in plasma after extrinsic or intrinsic activation with the same efficiency (IC50 0.1 - 0.6 μM) as hirudin. The delay and reduction of thrombin generation by inhibitors of the anion-binding exosite 1 of thrombin is only attributed to an inhibition of feed-back reactions of thrombin. For a 50% reduction of thrombin activity in plasma by this type of inhibitors relatively high concentrations were determined.

Cambiarenes: Single-Step Synthesis and Anion Binding of a Clip- Shaped Macrocycle with a Redox-Active Core

2019 ◽  
Author(s):  
Riley J. Petersen ◽  
Brett J. Rozeboom ◽  
Shalisa Oburn ◽  
Nolan Blythe ◽  
Tanner Rathje ◽  
...  
Keyword(s):  
Electron Density ◽  
Single Step ◽  
Anion Binding ◽  
Host Molecule ◽  
Selective Binding ◽  
The Core ◽  
Redox Active ◽  
Active Core ◽  
Guest Binding

<div>We report the synthesis of a novel macrocyclic host molecule that forms in a single step from commercially available starting materials. The core of the macrocycle backbone possesses two quinone rings and, thus, is redox-active. Host-guest binding involving the clip-shaped cavity indicates selective binding of pyridine <i>N</i>-oxides based of the electron density of and steric bulk of the anionic oxygen.</div>

scholarly journals Effects of anion binding on the deprotonation reactions of halorhodopsin.

1986 ◽  
Vol 261 (6) ◽  
pp. 2690-2696 ◽  
Author(s):  
B Schobert ◽  
J K Lanyi ◽  
D Oesterhelt
Keyword(s):  
Anion Binding

Pyrrole-bridged quinones: π-electronic systems that modulate electronic structures by tautomerism and deprotonation

2021 ◽  
Author(s):  
Shinya Sugiura ◽  
Hiromitsu Maeda
Keyword(s):  
Infrared Absorption ◽  
Electronic Structures ◽  
Near Infrared ◽  
Ion Pairing ◽  
Anion Binding ◽  
Electronic Systems

A new series of π-extended quinone derivatives containing a pyrrole bridge exhibited NH/OH-type tautomerization and anion binding along with deprotonation that induced near-infrared absorption and ion-pairing assemblies.

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