Comparison of urine collection methods for albuminuria assessment in young children

2016 ◽  
Vol 458 ◽  
pp. 120-123 ◽  
Author(s):  
S.M. van den Belt ◽  
V. Gracchi ◽  
D. de Zeeuw ◽  
H.J.L. Heerspink
Keyword(s):  
Young Children ◽  
Urine Collection ◽  
Collection Methods

scholarly journals Concentrations of Seven Phthalate Monoesters in Infants and Toddlers Quantified in Urine Extracted from Diapers

2021 ◽  
Vol 18 (13) ◽  
pp. 6806
Author(s):  
Fiorella Lucarini ◽  
Marc Blanchard ◽  
Tropoja Krasniqi ◽  
Nicolas Duda ◽  
Gaëlle Bailat Rosset ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Young Children ◽  
Sampling Technique ◽  
Gas Chromatography Mass Spectrometry ◽  
Urine Collection ◽  
Infants And Toddlers ◽  
Urine Sampling ◽  
Disposable Diapers ◽  
Children’S Exposure

Carrying out exposure studies on children who are not toilet trained is challenging because of the difficulty of urine sampling. In this study, we optimized a protocol for urine collection from disposable diapers for the analysis of phthalate metabolites. The exposure of Swiss children (n = 113) between 6 months and 3 years of life to seven phthalates was assessed by gas chromatography–mass spectrometry measurements. The study showed limited exposures to phthalates, with only 22% of the samples containing some of the metabolites investigated. The three most frequently detected metabolites were monoethyl phthalate, mono-cyclohexyl phthalate, and mono-benzyl phthalate. We also detected mono-n-octyl phthalate and mono(3,5,5-trimethylhexyl) phthalate, which have rarely been observed in urine from infants and toddlers; therefore, di-n-octyl phthalate and bis(3,5,5-trimethylhexyl) phthalate can be considered as potentially new emerging phthalates. This study presents an initial snapshot of the Swiss children’s exposure to phthalates and provides a promising approach for further phthalate biomonitoring studies on young children using disposable diapers as urine sampling technique.

Sign in / Sign up

Export Citation Format

Share Document