Role of S100B protein in urine and serum as an early predictor of mortality after severe traumatic brain injury in adults

2012 ◽  
Vol 414 ◽  
pp. 228-233 ◽  
Author(s):  
Ana Rodríguez-Rodríguez ◽  
Juan José Egea-Guerrero ◽  
Antonio León-Justel ◽  
Elena Gordillo-Escobar ◽  
Jaume Revuelto-Rey ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
S100b Protein ◽  
Urine And Serum ◽  
Early Predictor

scholarly journals The Role of Posttraumatic Hypothermia in Preventing Dendrite Degeneration and Spine Loss after Severe Traumatic Brain Injury

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Chuan-fang Wang ◽  
Cheng-cheng Zhao ◽  
Gan Jiang ◽  
Xiao Gu ◽  
Jun-feng Feng ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury

scholarly journals Early Dynamics of Cerebrospinal CD14+ Monocytes and CD15+ Granulocytes in Patients after Severe Traumatic Brain Injury: A Cohort Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Lukas Kurt Postl ◽  
Viktoria Bogner ◽  
Martijn van Griensven ◽  
Marc Beirer ◽  
Karl Georg Kanz ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Cohort Study ◽  
Brain Injury ◽  
Serum Albumin ◽  
Significant Influence ◽  
Severe Traumatic Brain Injury ◽  
Elective Surgery ◽  
Flow Analysis ◽  
Severe Tbi

In traumatic brain injury (TBI) the analysis of neuroinflammatory mechanisms gained increasing interest. In this context certain immunocompetent cells might play an important role. Interestingly, in the actual literature there exist only a few studies focusing on the role of monocytes and granulocytes in TBI patients. In this regard it has recently reported that the choroid plexus represents an early, selective barrier for leukocytes after brain injury. Therefore the aim of this study was to evaluate the very early dynamics of CD14+ monocytes and CD15+ granulocyte in CSF of patients following severe TBI with regard to the integrity of the BBB. Cytometric flow analysis was performed to analyze the CD14+ monocyte and CD15+ granulocyte population in CSF of TBI patients. The ratio of CSF and serum albumin as a measure for the BBB’s integrity was assessed in parallel. CSF samples of patients receiving lumbar puncture for elective surgery were obtained as controls. Overall 15 patients following severe TBI were enrolled. 10 patients were examined as controls. In patients, the monocyte population as well as the granulocyte population was significantly increased within 72 hours after TBI. The BBB’s integrity did not have a significant influence on the cell count in the CSF.

scholarly journals Electro-acupuncture Improved the Outcome of the Patient with Severe Traumatic Brain Injury: A Case Report.

2020 ◽  
pp. 1-4
Keyword(s):  
Traumatic Brain Injury ◽  
Case Report ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Traffic Accident ◽  
Vital Signs ◽  
Consciousness Disturbance ◽  
Strong Stimulation

Abstract This case report demonstrated that electro-acupuncture treatment has improved the outcome of an adolescent with severe traumatic brain injury due to a traffic accident. The patient had a bilateral frontal hematoma, subdural hematoma, subarachnoid hemorrhage, stem hematoma and diffuse parenchymal swelling with the initial Glasgow Coma Scale score of E1V1M1. Daily electro-acupuncture therapy was prescribed with strong stimulation at GV 26 (Shuigou), PC6 (Neiguan) and EX-UE11(Shixuan) when the vital signs of the patient became stable. The patient had a full recovery of the consciousness in 30 days. The follow-up observation found that he has also restored the motor and speech functions. This result suggested a potential role of electro-acupuncture in the treatment of consciousness disturbance for patient with traumatic brain injury.

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