Glutathione S-transferase as a biomarker in the Antarctic bivalve Laternula elliptica after exposure to the polychlorinated biphenyl mixture Aroclor 1254

2009 ◽  
Vol 150 (4) ◽  
pp. 528-536 ◽  
Author(s):  
Hyun Park ◽  
In-Young Ahn ◽  
Hakjun Kim ◽  
Jiyeon Lee ◽  
Seung Chul Shin
Keyword(s):  
Polychlorinated Biphenyl ◽  
Glutathione S Transferase ◽  
Aroclor 1254 ◽  
Laternula Elliptica ◽  
The Antarctic ◽  
Polychlorinated Biphenyl Mixture

Response of antioxidant defence systems to thermal stress in the Antarctic clamLaternula elliptica

2008 ◽  
Vol 20 (6) ◽  
pp. 521-526 ◽  
Author(s):  
Hyun Park ◽  
In-Young Ahn ◽  
Kyung-Il Park ◽  
Seunghun Hyun
Keyword(s):  
Antioxidant Enzymes ◽  
Thermal Stress ◽  
Digestive Gland ◽  
Protein Carbonyl ◽  
Transferase Activity ◽  
Glutathione S Transferase ◽  
Antioxidant Defence ◽  
Antioxidant Defences ◽  
Laternula Elliptica ◽  
The Antarctic

AbstractThe effects of thermal stress on antioxidant defences in tissues of the Antarctic clamLaternula ellipticawere evaluated and the activities of some antioxidant enzymes, and levels of total glutathione (GSH) and protein carbonyl (PC) in digestive gland and gill over 0–4 days under extreme thermal stress (10°C) were measured. Superoxide dismutase activity was slightly higher after one day of thermal stress, although catalase activity was not altered significantly in either digestive gland or gill tissues. Thermal stress was associated with a significant increase in the activity of GSH-related antioxidant enzymes. Glutathione peroxidase and glutathione reductase activities increased up to 1.8- and 2.0-fold, respectively, after two days of thermal stress. Glutathione S-transferase activity drastically increased, to over 3.4- and 4.2-fold in digestive gland and gill, respectively, and remained high on day four. GSH levels also increased in both tissues and remained high on day four. PC content, a marker of protein oxidation, increased after two days of thermal stress. There is evidence that GSH-related antioxidant defence plays a significant role in relation to potential toxicity from reactive oxygen species during thermal stress.

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