β-Carotene from cassava (Manihot esculenta Crantz) leaves improves vitamin A status in rats

2007 ◽  
Vol 146 (1-2) ◽  
pp. 235-240 ◽  
Author(s):  
Egle Machado de Almeida Siqueira ◽  
Sandra Fernandes Arruda ◽  
Rodrigo Martins de Vargas ◽  
Elizabeth Maria Talá de Souza
Keyword(s):  
Vitamin A ◽  
Manihot Esculenta ◽  
Manihot Esculenta Crantz ◽  
Vitamin A Status ◽  
Β Carotene

scholarly journals UV-visible scanning spectrophotometry and chemometric analysis as tools for carotenoids analysis in cassava genotypes (Manihot esculenta Crantz)

2015 ◽  
Vol 12 (4) ◽  
pp. 27-38
Author(s):  
Rodolfo Moresco ◽  
Virgílio G. Uarrota ◽  
Aline Pereira ◽  
Maíra Tomazzoli ◽  
Eduardo da C. Nunes ◽  
...  
Keyword(s):  
Vitamin A ◽  
Manihot Esculenta ◽  
High Performance ◽  
Vitamin A Deficiency ◽  
Chemometric Analysis ◽  
Manihot Esculenta Crantz ◽  
Data Set ◽  
Health And Nutrition ◽  
Uv Visible ◽  
Β Carotene

Summary In this study, the metabolomics characterization focusing on the carotenoid composition of ten cassava (Manihot esculenta) genotypes cultivated in southern Brazil by UV-visible scanning spectrophotometry and reverse phase-high performance liquid chromatography was performed. Cassava roots rich in β-carotene are an important staple food for populations with risk of vitamin A deficiency. Cassava genotypes with high pro-vitamin A activity have been identified as a strategy to reduce the prevalence of deficiency of this vitamin. The data set was used for the construction of a descriptive model by chemometric analysis. The genotypes of yellow-fleshed roots were clustered by the higher concentrations of cis- β-carotene and lutein. Inversely, cream-fleshed roots genotypes were grouped precisely due to their lower concentrations of these pigments, as samples rich in lycopene (redfleshed) differed among the studied genotypes. The analytical approach (UV-Vis, HPLC, and chemometrics) used showed to be efficient for understanding the chemodiversity of cassava genotypes, allowing to classify them according to important features for human health and nutrition.

scholarly journals Retention of total carotenoid and β-carotene in yellow sweet cassava (Manihot esculenta Crantz) after domestic cooking

2012 ◽  
Vol 56 (1) ◽  
pp. 15788 ◽  
Author(s):  
LuciaM. J. Carvalho ◽  
AlcidesR. G. Oliveira ◽  
RonoelL. O. Godoy ◽  
Sidney Pacheco ◽  
MaríliaR. Nutti ◽  
...  
Keyword(s):  
Manihot Esculenta ◽  
Total Carotenoid ◽  
Manihot Esculenta Crantz ◽  
Β Carotene ◽  
Sweet Cassava

scholarly journals Cassava with enhanced β-carotene maintains adequate vitamin A status in Mongolian gerbils (Meriones unguiculatus) despite substantial cis-isomer content

2009 ◽  
Vol 102 (3) ◽  
pp. 342-349 ◽  
Author(s):  
Julie A. Howe ◽  
Bussie Maziya-Dixon ◽  
Sherry A. Tanumihardjo
Keyword(s):  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Meriones Unguiculatus ◽  
Provitamin A ◽  
Carotenoid Content ◽  
Mongolian Gerbils ◽  
Serum Retinol ◽  
Vitamin A Status ◽  
Isomer Content ◽  
Β Carotene

Efforts to increase β-carotene in cassava have been successful, but the ability of high-β-carotene cassava to prevent vitamin A deficiency has not been determined. Two studies investigated the bioefficacy of provitamin A in cassava and compared the effects of carotenoid content and variety on vitamin A status in vitamin A-depleted Mongolian gerbils (Meriones unguiculatus). Gerbils were fed a vitamin A-free diet 4 weeks prior to treatment. In Expt 1, treatments (ten gerbils per group) included 45 % high-β-carotene cassava, β-carotene and vitamin A supplements (intake matched to high-β-carotene cassava group), and oil control. In Expt 2, gerbils were fed cassava feeds with 1·8 or 4·3 nmol provitamin A/g prepared with two varieties. Gerbils were killed after 4 weeks. For Expt 1, liver vitamin A was higher (P < 0·05) in the vitamin A (1·45 (sd 0·23) μmol/liver), lower in the control (0·43 (sd 0·10) μmol/liver), but did not differ from the β-carotene group (0·77 (sd 0·12) μmol/liver) when compared with the high-β-carotene cassava group (0·69 (sd 0·20) μmol/liver). The bioconversion factor was 3·7 μg β-carotene to 1 μg retinol (2 mol:1 mol), despite 48 % cis-β-carotene [(Z)-β-carotene] composition in cassava. In Expt 2, cassava feed with 4·3 nmol provitamin A/g maintained vitamin A status. No effect of cassava variety was observed. Serum retinol concentrations did not differ. β-Carotene was detected in livers of gerbils receiving cassava and supplements, but the cis-to-trans ratio in liver differed from intake. Biofortified cassava adequately maintained vitamin A status and was as efficacious as β-carotene supplementation in the gerbil model.

scholarly journals Daily consumption of pro-vitamin A biofortified (yellow) cassava improves serum retinol concentrations in preschool children in Nigeria: a randomized controlled trial

2020 ◽  
Vol 113 (1) ◽  
pp. 221-231
Author(s):  
Ibukun Afolami ◽  
Martin N Mwangi ◽  
Folake Samuel ◽  
Erick Boy ◽  
Paul Ilona ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Preschool Children ◽  
Vitamin A ◽  
Controlled Trial ◽  
Asymptomatic Malaria ◽  
Serum Retinol ◽  
Daily Consumption ◽  
Randomized Controlled ◽  
Vitamin A Status ◽  
Β Carotene

ABSTRACT Background Vitamin A deficiency is a public health problem in sub-Saharan Africa. Pro-vitamin A biofortified (yellow) cassava has the potential to contribute significantly to improve vitamin A status, especially in populations that are difficult to reach with other strategies. Objectives The study aimed at determining the efficacy of biofortified cassava to improve vitamin A status of Nigerian preschool children. Methods An open-label randomized controlled trial was conducted in southwestern Nigeria. In total, 176 preschool children (aged 3–5 y) were randomized into 2 parallel arms comprising an experimental group (n = 88), fed foods prepared from biofortified (yellow) cassava, and a control group (n = 88), fed foods prepared from white cassava, twice a day, 6 d a week for 93 d. Results A total of 159 children completed the trial (yellow cassava group, n = 80; white cassava group, n = 79). Children consumed 221 and 74 µg/d retinol activity equivalents from intervention foods in the yellow and white cassava groups, respectively. The treatment effect on serum retinol concentrations at the end of the feeding trial was 0.06 µmol/L (95% CI: 0.004, 0.124 µmol/L), after adjustment for baseline retinol concentrations, inflammation, and asymptomatic malaria status. No significant treatment effects were detected for serum β-carotene (adjusted effect: 3.9%; 95% CI: −0.6%, 8.6%) and gut permeability (adjusted effect: 0.002; 95% CI: −0.089, 0.092), but a significant effect was detected for hemoglobin concentrations (adjusted effect: 3.08 g/L; 95% CI: 0.38, 5.78 g/L). Conclusions Daily consumption of β-carotene from biofortified cassava improved serum retinol and hemoglobin concentrations modestly in Nigerian preschool children. This study was registered with clinicaltrials.gov as NCT02627222.

scholarly journals FORMULASI FLAKES UBI KAYU (Manihot esculenta Crantz) SEBAGAI PENGGANTI SARAPAN YANG BERPOTENSI ANTIOKSIDAN

2015 ◽  
Vol 5 (1) ◽  
pp. 1-10
Author(s):  
Eka Herlina ◽  
Farida Nuraeni
Keyword(s):  
Vitamin E ◽  
Vitamin A ◽  
Vitamin C ◽  
Manihot Esculenta ◽  
Manihot Esculenta Crantz

Diversifikasi produk pangan merupakan salah satu cara untuk menunjang ketahanan pangan. Ubi kayu (Manihot esculenta Crantz) dapat digunakan sebagai bahan pangan alternatif pengganti beras yang diolah menjadi flakes. Salah satu komponen bioaktif pada ubikayu yaitu skopoletin suatu senyawa fenolik yang mempunyai aktivitas antioksidan. Penelitian ini dilakukan dengan cara mensubstitusi tepung ubi kayu pada pembuatan flakesubi kayu menggunakan tepung kacang merah dengan berbagai perbandingan tepung ubikayu : tepung kacang merah yaitu 5:0, 4:1, 3:2, 2:3 dan 1:4. Produk olahan dianalisiskandungan vitamin C, A, E, tingkat penerimaan dengan uji organoleptik dan uji aktivitasantioksidan dengan metode DPPH (1,1-difenil-2-pikrilhidrazil). Analisis kadar vitamin Cmenggunakan metode spektrofotometri, sedangkan vitamin A dan E dengan metode HPLC.Hasil penelitian menunjukkan flakes ubi kayu dengan penambahan tepung kacang merahpada formula flakes 3:2 merupakan formulasi yang lebih disukai oleh panelis, dengankandungan vitamin C 5,23 ppm, vitamin A 166,05 IU/100 gram, nilai IC50397,06 ppm, dantidak mengandung vitamin E.

scholarly journals Development of nanoparticles coated with cassava bagasse pectin (Manihot esculenta Crantz) containing β-carotene for mucoadhesive applications

2020 ◽  
Vol 92 (4) ◽  
Author(s):  
BIANCA COELHO ◽  
LETÍCIA MAZZARINO ◽  
HELOÍSA S. PITZ ◽  
CLARISSA FELTRIN ◽  
ANA PAULA L. VOYTENA ◽  
...  
Keyword(s):  
Manihot Esculenta ◽  
Manihot Esculenta Crantz ◽  
Cassava Bagasse ◽  
Β Carotene
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