Case studies in current drug development: ‘glycylcyclines’

2006 ◽  
Vol 10 (4) ◽  
pp. 374-379 ◽  
Author(s):  
Phaik-Eng Sum
2019 ◽  
Author(s):  
Christopher Southan

This report covers academic small-molecule drug development with a view to distilling guidelines. The first section covers research productivity feeding into commercial development before reviewing the literature on statistics of academic development It then considers differences between probes and drugs before discussing the role of author guidelines in medicinal chemistry and pharmacology journals. Resources for comprehensive compound and target cross-checking are then covered followed by comparisons between public and commercial databases including case studies of selected compounds. It concludes with an outline of new scientific developments that could increase the success rate of academic drug development.


2019 ◽  
Author(s):  
Christopher Southan

This report covers academic small-molecule drug development with a view to distilling guidelines. The first section covers research productivity feeding into commercial development before reviewing the literature on statistics of academic development It then considers differences between probes and drugs before discussing the role of author guidelines in medicinal chemistry and pharmacology journals. Resources for comprehensive compound and target cross-checking are then covered followed by comparisons between public and commercial databases including case studies of selected compounds. It concludes with an outline of new scientific developments that could increase the success rate of academic drug development.


1974 ◽  
Vol 4 (3) ◽  
pp. 260-263
Author(s):  
James Turner

Although critical of several specific drug industry practices as being major contributions to the current over-medicated society controversy, Mr. Turner believes that the pharmaceutical industry can work together with consumer organizations and the public sector in resolving these issues. Of particular interest is his observation that the economic structure of current drug development and research prevents the manufacturer from assessing the impact of a drug in terms of necessary health benefits.


2005 ◽  
Vol 5 (5) ◽  
pp. 473-478 ◽  
Author(s):  
G BIAGINI ◽  
P ONEILL ◽  
P BRAY ◽  
S WARD

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