A green catalytic method for selective synthesis of iodophenols via aerobic oxyiodination under organic solvent-free conditions

2017 ◽  
Vol 93 ◽  
pp. 1-4 ◽  
Author(s):  
Hongchuan Xin ◽  
Liangning Hu ◽  
Jianqiang Yu ◽  
Wenshou Sun ◽  
Zengjian An
Keyword(s):  
Organic Solvent ◽  
Solvent Free ◽  
Selective Synthesis ◽  
Catalytic Method ◽  
Solvent Free Conditions

scholarly journals Green synthesis of new lawsone enaminones and their Z/E(CC)-isomerization induced by organic solvent

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 12990-12994
Author(s):  
Abolfazl Olyaei ◽  
Amir Mohamadi ◽  
Nilufar Rahmani
Keyword(s):  
Organic Solvent ◽  
Green Synthesis ◽  
Aromatic Amines ◽  
Solvent Free ◽  
Triethyl Orthoformate ◽  
Guanidinium Chloride ◽  
New Class ◽  
Solvent Free Conditions

The synthesis of a new class of lawsone enaminone derivatives by using lawsone, triethyl orthoformate and aromatic amines in the presence of guanidinium chloride under solvent-free conditions has been developed.

Selective synthesis of conjugated enynes from α-arylalkynols using LiCl-Acidic Al2O3 under solvent-free conditions

2002 ◽  
Vol 2002 (8) ◽  
pp. 378-380 ◽  
Author(s):  
Ali Pourjavadi ◽  
Gholam Bagheri Marandi
Keyword(s):  
Solvent Free ◽  
Selective Synthesis ◽  
Solvent Free Conditions ◽  
Conjugated Enynes

α-Arylalkynols were converted into conjugated enynes (in a selective manner under solvent-free conditions) using the LiCl-acidic Al2O3 couple as catalyst and support.

scholarly journals The two-step mechanochemical synthesis of porphyrins

2014 ◽  
Vol 170 ◽  
pp. 59-69 ◽  
Author(s):  
Hannah Shy ◽  
Paula Mackin ◽  
Andrea S. Orvieto ◽  
Deepa Gharbharan ◽  
Geneva R. Peterson ◽  
...  
Keyword(s):  
Organic Solvent ◽  
Mechanochemical Synthesis ◽  
Bond Formation ◽  
Acid Catalyst ◽  
Solvent Free ◽  
Oxidizing Agent ◽  
Carbon Bond ◽  
Carbon Carbon Bond ◽  
Solvent Free Conditions ◽  
Porphyrin Synthesis

Porphyrin synthesis under solvent-free conditions represents the “greening” of a traditional synthesis that normally requires large amounts of organic solvent, and has hindered the industrial-scale synthesis of this useful class of molecules. We have found that the four-fold acid-catalysed condensation of aldehyde and pyrrole to yield a tetra-substituted porphyrin is possible through mechanochemical techniques, without a solvent present. This represents one of the still-rare examples of carbon–carbon bond formation by mechanochemistry. Specifically, upon grinding equimolar amounts of pyrrole and benzaldehyde in the presence of an acid catalyst, cyclization takes place to give reduced porphyrin precursors (reversible), which upon oxidation form tetraphenylporphyrin (TPP). The approach has been found to be suitable for the synthesis of a variety of meso-tetrasubstituted porphyrins. Oxidation can occur either by using an oxidizing agent in solution, to give yields comparable to those published for traditional methods of porphyrin synthesis, or through mechanochemical means resulting in a two-step mechanochemical synthesis to give slightly lower yields that are still being optimized. We are also working on “green” methods of porphyrin isolation, including entrainment sublimation, which would hopefully further reduce the need for large amounts of organic solvent. These results hold promise for the development of mechanochemical synthetic protocols for porphyrins and related classes of compounds.

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