scholarly journals Loeffler Endocarditis: A Manifestation of Hypereosinophilic Syndrome

CASE ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 74-77
Author(s):  
Michael Arustamyan ◽  
Jamael Hoosain ◽  
Jennifer Mattson ◽  
Syed Farhan Hasni ◽  
Sung-Hae Cho ◽  
...  
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Loeffler Endocarditis

scholarly journals Loeffler endocarditis with intracardiac thrombus: case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qian Zhang ◽  
Daoyuan Si ◽  
Zhongfan Zhang ◽  
Wenqi Zhang
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Anticoagulation Therapy ◽  
Intracardiac Thrombus ◽  
Case Presentation ◽  
Life Threatening ◽  
Characteristic Features ◽  
Poor Outcomes ◽  
Loeffler Endocarditis ◽  
Significant Mortality

Abstract Background Loeffler endocarditis is a relatively rare and potentially life-threatening heart disease. This study aimed to identify the characteristic features of Loeffler endocarditis with intracardiac thrombus on a background of hypereosinophilic syndrome (HES). Case presentation We described a 57-year-old woman with Loeffler endocarditis and intracardiac thrombus initially presenting with neurological symptoms, who had an embolic stroke in the setting of HES. After cardiac magnetic resonance (CMR), corticosteroids and warfarin were administered to control eosinophilia and thrombi, respectively. During a 10-month follow-up, the patient performed relatively well, with no adverse events. We also systematically searched PubMed and Embase for cases of Loeffler endocarditis with intracardiac thrombus published until July 2021. A total of 32 studies were eligible and included in our analysis. Further, 36.4% of recruited patients developed thromboembolic complications, and the mortality rate was relatively high (27.3%). CMR was a powerful noninvasive modality in providing diagnostic and follow-up information in these patients. Steroids were administered in 81.8% of patients, achieving a rapid decrease in the eosinophil count. Also, 69.7% of patients were treated with anticoagulant therapy, and the thrombus was completely resolved in 42.4% of patients. Heart failure and patients not treated with anticoagulation were associated with poor outcomes. Conclusions Cardiac involvement in HES, especially Loeffler endocarditis with intracardiac thrombus, carries a pessimistic prognosis and significant mortality. Early steroids and anticoagulation therapy may be beneficial once a working diagnosis is established. Further studies are needed to provide evidence-based evidence for managing this uncommon manifestation of HES.

scholarly journals Loeffler Endocarditis: A Unique Presentation of Right-Sided Heart Failure Due to Eosinophil-Induced Endomyocardial Fibrosis

2017 ◽  
Vol 10 ◽  
pp. 117954761772364 ◽  
Author(s):  
Amit Alam ◽  
Shankar Thampi ◽  
Shahryar G Saba ◽  
Rita Jermyn
Keyword(s):  
Heart Failure ◽  
Surgical Intervention ◽  
Diastolic Heart Failure ◽  
Treatment Options ◽  
Hypereosinophilic Syndrome ◽  
Restrictive Cardiomyopathy ◽  
Endomyocardial Fibrosis ◽  
History Of ◽  
The Right ◽  
Loeffler Endocarditis

Loeffler endocarditis is a rare restrictive cardiomyopathy caused by abnormal endomyocardial infiltration of eosinophils, with subsequent tissue damage from degranulation, eventually leading to fibrosis. Although an uncommon entity, it is still a disease with significant morbidity and mortality. Often identified only at late stages, treatment options are limited once fibrosis occurs, usually requiring heart failure medications or surgical intervention. We present a unique case of a woman with remote history of hypereosinophilic syndrome, attributed to treatment of rheumatoid arthritis with infliximab, who presented with symptoms of heart failure refractory to medical management and was found to have Loeffler endocarditis. The severe progression of the disease required surgical intervention with endocardial stripping to treat the right-sided diastolic heart failure.

scholarly journals Hypereosinophilic syndrome with Loeffler endocarditis

2017 ◽  
Vol 12 (4) ◽  
pp. 141-141
Author(s):  
Urška Dolores Breskvar Kač ◽  
Ljupka Dimitrovska ◽  
Jana Ambrožič ◽  
Mojca Bervar
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Loeffler Endocarditis

Acute lung failure due to hypereosinophilic syndrome after pneumonectomy

2019 ◽  
Author(s):  
G Yavuz ◽  
T Kauke ◽  
OM Glück ◽  
T Weig ◽  
K Milger-Kneidinger ◽  
...  
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Acute Lung Failure ◽  
Lung Failure

Hypereosinophilic syndrome: Clinical, laboratory, and imaging manifestations in patients with hepatic involvement

1993 ◽  
Vol 29 (4) ◽  
pp. 757
Author(s):  
Gi Beom Kim ◽  
Ok Hwoa Kim ◽  
Jong Min Lee ◽  
Yeong Soon Sung ◽  
Duk Sik Kang
Keyword(s):  
Clinical Laboratory ◽  
Hypereosinophilic Syndrome ◽  
Hepatic Involvement

Idiopathic Hypereosinophilic Syndrome Involving the Liver: CT Features vs. Peripheral Eosinophilia

1997 ◽  
Vol 37 (4) ◽  
pp. 673 ◽  
Author(s):  
Kyung Sook Kim ◽  
Moon Gyu Lee ◽  
Young Chul Won ◽  
Eun Hye Lee ◽  
Han Na Noh ◽  
...  
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Idiopathic Hypereosinophilic Syndrome ◽  
Peripheral Eosinophilia ◽  
Liver Ct ◽  
Ct Features

A Case of Hypereosinophilic Syndrome.

1991 ◽  
Vol 53 (3) ◽  
pp. 525-529 ◽  
Author(s):  
Kenichi MORI ◽  
Mamoru KOHDA ◽  
Yasuji MORI ◽  
Hiroaki UEKI ◽  
Masahiko KUMAGAI
Keyword(s):  
Hypereosinophilic Syndrome
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