Effects of High-Intensity Interval Exercise Training on Skeletal Myopathy of Chronic Heart Failure

2017 ◽  
Vol 23 (1) ◽  
pp. 36-46 ◽  
Author(s):  
Georgios Tzanis ◽  
Anastassios Philippou ◽  
Eleftherios Karatzanos ◽  
Stavros Dimopoulos ◽  
Elisavet Kaldara ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Exercise Training ◽  
High Intensity ◽  
Interval Exercise ◽  
Skeletal Myopathy ◽  
High Intensity Interval

scholarly journals HIGH-INTENSITY INTERVAL EXERCISE IN CHRONIC HEART FAILURE: COMPARISON OF CARBOHYDRATE AND LIPID OXIDATION

2015 ◽  
Vol 31 (10) ◽  
pp. S266
Author(s):  
P.A. Ribeiro ◽  
E. Normandin ◽  
M. Gayda ◽  
P. Meyer ◽  
M. Juneau ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Lipid Oxidation ◽  
High Intensity ◽  
Interval Exercise ◽  
High Intensity Interval

High-Intensity Interval Exercise in Chronic Heart Failure: Protocol Optimization

2012 ◽  
Vol 18 (2) ◽  
pp. 126-133 ◽  
Author(s):  
Philippe Meyer ◽  
Eve Normandin ◽  
Mathieu Gayda ◽  
Guillaume Billon ◽  
Thibaut Guiraud ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
High Intensity ◽  
Interval Exercise ◽  
Protocol Optimization ◽  
High Intensity Interval

High-Intensity Interval Exercise Improves Vagal Tone and Decreases Arrhythmias in Chronic Heart Failure

2013 ◽  
Vol 45 (10) ◽  
pp. 1861-1867 ◽  
Author(s):  
THIBAUT GUIRAUD ◽  
MARC LABRUNEE ◽  
KEVIN GAUCHER-CAZALIS ◽  
FABIEN DESPAS ◽  
PHILIPPE MEYER ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
High Intensity ◽  
Vagal Tone ◽  
Interval Exercise ◽  
High Intensity Interval

P638High intensity interval exercise training improves endothelial function in patients with heart failure with preserved ejection fraction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Deljanin Ilic ◽  
G Kocic ◽  
D Simonovic ◽  
R Pavlovic ◽  
S Ilic ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Exercise Training ◽  
Endothelial Function ◽  
High Intensity ◽  
Moderate Intensity ◽  
Preserved Ejection Fraction ◽  
Interval Exercise ◽  
Continuous Exercise ◽  
High Intensity Interval

Abstract Background Cardiac rehabilitation has traditionally invoved low-to moderate intensity continuous exercise training (MICT). There is growing evidence that high intensity interval exercise training (HIIT) shows similar or greater efficacy compared with MICT. However, the relationship between the training modality and its effects on endothelial function still remains to be elucidated. Purpose To evaluate the impact of high intensity interval exercise training versus low-to moderate intensity continuous exercise training on circulating blood markers of endothelial function: the stable end product of nitric oxide (NOx), S–nitrosothiols (RSNO–reservoir for bioavailable nitric oxide), dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) in patients (pts) with heart failure with preserved ejection fraction (HFpEF). Methods A total of 43 pts with HFpEF (mean age 57.5±6.8y) admitted at residential rehabilitation center were enrolled in the study. Patients were randomized to HIIT, (HIIT group, n=20) and MICT, (MICTgroup, n=23). At baseline and 3 weeks later, in all pts values of NOx, RSNO, ADMA and SDMA were determined and exercise test was performed. Results After 3 weeks NOx increased significantly in both groups: in HIITgroup (from 34.7±7.5 to 48.5±8.3 μmol/l, P<0.0001), in MICTgroup (from 35.0±9.5 to 42.5±10.0 μmol/l, P<0.05), and value of NOx after 3 weeks was higher in HIIT than in MICT group (P<0.05). Value of ADMA as well of SDMA decreased in both groups after 3 weeks, and this decrease was significant in HIIT group: ADMA in HIIT group (from 0.305±0.055 to 0.250±0.077 μmol/l, P<0.005) and in MICT group (from 0.325±0.069 to 0.280±0.140 μmol/l, ns); SDMA in HIIT group (from 0.285±0.050 to 0.240±0.060 μmol/l, P<0,005) and in MICT group (from 0.270±0.080 to 0.247±0.063 μmol/l, ns). Value of RSNO significantly increased in both groups, with higher increase in HIIT group: in HIIT group (from 3.0±1.5 to 5.1±1.7 μmol/l, P<0.001), in MICTgroup (from 3.2±1.7 to 4.5±2.3 μmol/l, P<0.05). Compared to the baseline, at the end of the study, exercise capacity (METs) was significantly higher in both groups (P<0.0001). Higher increase in METs in HIIT group during exercise training (by 39.8%), compared to increase in MICT group (by 27.2%), resulted in significantly higher exercise tolerance in HIIT than in MICT group at the end of the study (P<0.02). In both groups, adverse events during or after exercise training, were not occurred. Conclusions In pts with HFpEF high intensity interval exercise training as well as low-to moderate intensity continuous exercise training induced favorable modification of endothelial function, expressed through increase of NOx and RSNO, and decrease of ADMA and SDMA. More significant increase of NOx and RSNO, and significant decrease of ADMA and SDMA gives an advantage to HIIT over MICT exercise training in patients with HFpEF.

High-Intensity Aerobic Interval Exercise in Chronic Heart Failure

2013 ◽  
Vol 10 (2) ◽  
pp. 130-138 ◽  
Author(s):  
Philippe Meyer ◽  
Mathieu Gayda ◽  
Martin Juneau ◽  
Anil Nigam
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
High Intensity ◽  
Interval Exercise
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